SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ww3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		3 / 3 GLU A 113
HIS A 188
HIS A 108
 MN  A 401 (-2.5A)
MN  A 401 (-3.5A)
MN  A 401 (-3.3A)
 0.67A 1oe2A-3ww3A:
1.1		 1oe2A-3ww3A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 5 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 MN  A 401 (-3.5A)
MN  A 401 (-2.5A)
MN  A 401 (-3.3A)
MN  A 401 (-3.4A)
 1.07A 1os2A-3ww3A:
undetectable		 1os2A-3ww3A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 MN  A 401 (-3.5A)
MN  A 401 (-2.5A)
MN  A 401 (-3.3A)
MN  A 401 (-3.4A)
 1.07A 1os2D-3ww3A:
undetectable		 1os2D-3ww3A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 7 GLU A 204
HIS A 108
MET A  63
ILE A  65
 None
MN  A 401 (-3.3A)
None
None
 0.90A 1tuvA-3ww3A:
undetectable		 1tuvA-3ww3A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 7 TYR A 115
GLU A 204
MET A  63
ILE A  65
 None
 1.17A 1tuvA-3ww3A:
undetectable		 1tuvA-3ww3A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 MN  A 401 (-3.5A)
MN  A 401 (-2.5A)
MN  A 401 (-3.3A)
MN  A 401 (-3.4A)
 1.10A 1utzA-3ww3A:
undetectable		 1utzA-3ww3A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 MN  A 401 (-3.5A)
MN  A 401 (-2.5A)
MN  A 401 (-3.3A)
MN  A 401 (-3.4A)
 1.14A 1utzB-3ww3A:
undetectable		 1utzB-3ww3A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 MN  A 401 (-3.5A)
MN  A 401 (-2.5A)
MN  A 401 (-3.3A)
MN  A 401 (-3.4A)
 1.10A 2hu6A-3ww3A:
undetectable		 2hu6A-3ww3A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 MN  A 401 (-3.5A)
MN  A 401 (-2.5A)
MN  A 401 (-3.3A)
MN  A 401 (-3.4A)
 1.11A 2ow9B-3ww3A:
undetectable		 2ow9B-3ww3A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 MN  A 401 (-3.5A)
MN  A 401 (-2.5A)
MN  A 401 (-3.3A)
MN  A 401 (-3.4A)
 1.10A 2ozrC-3ww3A:
undetectable		 2ozrC-3ww3A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 MN  A 401 (-3.5A)
MN  A 401 (-2.5A)
MN  A 401 (-3.3A)
MN  A 401 (-3.4A)
 1.08A 2ozrD-3ww3A:
undetectable		 2ozrD-3ww3A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 5 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 MN  A 401 (-3.5A)
MN  A 401 (-2.5A)
MN  A 401 (-3.3A)
MN  A 401 (-3.4A)
 1.11A 3likA-3ww3A:
undetectable		 3likA-3ww3A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 MN  A 401 (-3.5A)
MN  A 401 (-2.5A)
MN  A 401 (-3.3A)
MN  A 401 (-3.4A)
 1.13A 3lilA-3ww3A:
undetectable		 3lilA-3ww3A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 5 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 MN  A 401 (-3.5A)
MN  A 401 (-2.5A)
MN  A 401 (-3.3A)
MN  A 401 (-3.4A)
 1.09A 3lkaA-3ww3A:
undetectable		 3lkaA-3ww3A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		5 / 9 ALA A  18
TYR A  47
ILE A   6
GLY A  39
ALA A  38
 None
 1.19A 4r1zA-3ww3A:
undetectable		 4r1zA-3ww3A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 4 HIS A 188
GLU A 113
HIS A 108
HIS A 106
 MN  A 401 (-3.5A)
MN  A 401 (-2.5A)
MN  A 401 (-3.3A)
MN  A 401 (-3.4A)
 1.12A 5n5jA-3ww3A:
undetectable		 5n5jA-3ww3A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 4 HIS A 106
HIS A 188
TYR A 115
GLU A 113
 MN  A 401 (-3.4A)
MN  A 401 (-3.5A)
None
MN  A 401 (-2.5A)
 1.31A 5pahA-3ww3A:
undetectable		 5pahA-3ww3A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		4 / 4 HIS A 108
HIS A 188
TYR A 115
GLU A 113
 MN  A 401 (-3.3A)
MN  A 401 (-3.5A)
None
MN  A 401 (-2.5A)
 1.16A 5pahA-3ww3A:
undetectable		 5pahA-3ww3A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 3ww3 L-RIBOSE ISOMERASE
(Cellulomonas
parahominis) 		3 / 3 HIS A 106
HIS A 188
HIS A 108
 MN  A 401 (-3.4A)
MN  A 401 (-3.5A)
MN  A 401 (-3.3A)
 0.36A 5zrdA-3ww3A:
undetectable		 5zrdA-3ww3A:
18.07