SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wwk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		3 / 3 TRP A  71
VAL A 130
TRP A  26
 None
 1.31A 1c4dC-3wwkA:
undetectable
1c4dD-3wwkA:
undetectable		 1c4dC-3wwkA:
8.09
1c4dD-3wwkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		3 / 3 VAL A 130
TRP A  26
TRP A  71
 None
 1.23A 2xdcA-3wwkA:
undetectable
2xdcB-3wwkA:
undetectable		 2xdcA-3wwkA:
8.09
2xdcB-3wwkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		3 / 3 TRP A  71
VAL A 130
TRP A  26
 None
 1.24A 2xdcA-3wwkA:
undetectable
2xdcB-3wwkA:
undetectable		 2xdcA-3wwkA:
8.09
2xdcB-3wwkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		3 / 3 VAL A 130
TRP A  26
TRP A  71
 None
 1.29A 2xdcC-3wwkA:
undetectable
2xdcD-3wwkA:
undetectable		 2xdcC-3wwkA:
8.09
2xdcD-3wwkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		3 / 3 TRP A  71
VAL A 130
TRP A  26
 None
 1.00A 2xdcC-3wwkA:
undetectable
2xdcD-3wwkA:
undetectable		 2xdcC-3wwkA:
8.09
2xdcD-3wwkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		3 / 3 TRP A  71
VAL A 130
TRP A  26
 None
 1.03A 2xdcE-3wwkA:
undetectable
2xdcF-3wwkA:
undetectable		 2xdcE-3wwkA:
8.09
2xdcF-3wwkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		3 / 3 VAL A 130
TRP A  26
TRP A  71
 None
 1.22A 2y5mA-3wwkA:
undetectable
2y5mB-3wwkA:
undetectable		 2y5mA-3wwkA:
8.09
2y5mB-3wwkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		3 / 3 TRP A  71
VAL A 130
TRP A  26
 None
 1.00A 2y5mE-3wwkA:
undetectable
2y5mF-3wwkA:
undetectable		 2y5mE-3wwkA:
8.09
2y5mF-3wwkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		3 / 3 VAL A 130
TRP A  26
TRP A  71
 None
 1.21A 2y6nA-3wwkA:
undetectable
2y6nB-3wwkA:
undetectable		 2y6nA-3wwkA:
8.09
2y6nB-3wwkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		3 / 3 TRP A  71
VAL A 130
TRP A  26
 None
 1.23A 2y6nA-3wwkA:
undetectable
2y6nB-3wwkA:
undetectable		 2y6nA-3wwkA:
8.09
2y6nB-3wwkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		3 / 3 TRP A  71
VAL A 130
TRP A  26
 None
 0.98A 2y6nC-3wwkA:
undetectable
2y6nD-3wwkA:
undetectable		 2y6nC-3wwkA:
8.09
2y6nD-3wwkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		3 / 3 TRP A  71
VAL A 130
TRP A  26
 None
 0.98A 2y6nE-3wwkA:
undetectable
2y6nF-3wwkA:
undetectable		 2y6nE-3wwkA:
8.09
2y6nF-3wwkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		5 / 12 GLU A 124
ASP A  27
TRP A  71
ALA A  76
ASN A  78
 None
 1.29A 3ticA-3wwkA:
undetectable		 3ticA-3wwkA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		3 / 3 VAL A 130
TRP A  26
TRP A  71
 None
 1.22A 3zq8A-3wwkA:
undetectable
3zq8B-3wwkA:
undetectable		 3zq8A-3wwkA:
8.09
3zq8B-3wwkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3wwk SNACLEC RHODOCYTIN
SUBUNIT ALPHA
(Calloselasma
rhodostoma) 		4 / 6 LEU A 134
ASP A  13
VAL A 130
ALA A  43
 None
 1.01A 4nkxA-3wwkA:
undetectable		 4nkxA-3wwkA:
13.88