SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wx7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 11 LEU A  77
LEU A 142
ALA A 161
ALA A 157
LEU A  84
 None
 1.36A 1iiuA-3wx7A:
undetectable		 1iiuA-3wx7A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		3 / 3 ASN A 167
TRP A 169
GLN A 273
 None
 0.92A 1xoqA-3wx7A:
undetectable		 1xoqA-3wx7A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		4 / 7 SER A 204
SER A 124
SER A 184
THR A 183
 None
 1.05A 2i91A-3wx7A:
undetectable		 2i91A-3wx7A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		4 / 7 SER A 204
SER A 124
SER A 184
THR A 183
 None
 1.05A 2i91B-3wx7A:
undetectable		 2i91B-3wx7A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		4 / 5 PHE A 249
PHE A 314
PHE A 325
VAL A 227
 None
 1.26A 2lh6A-3wx7A:
undetectable		 2lh6A-3wx7A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		3 / 3 SER A 110
ASP A  66
ASP A  96
 None
 0.79A 2plwA-3wx7A:
undetectable		 2plwA-3wx7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_1
(HYPOTHETICAL PROTEIN)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		4 / 4 GLU A  73
ASP A  66
ASP A  36
TYR A  95
 None
None
ZN  A 902 ( 2.5A)
None
 1.37A 2yvlA-3wx7A:
1.3		 2yvlA-3wx7A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 12 PHE A 295
VAL A  45
PHE A 325
ALA A 246
PHE A 314
 None
 1.26A 3apxA-3wx7A:
undetectable		 3apxA-3wx7A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 12 ALA A 256
VAL A 253
PHE A 314
LEU A 311
LEU A 243
 None
 0.91A 3b0wB-3wx7A:
undetectable		 3b0wB-3wx7A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		4 / 6 TYR A 323
ASN A 258
LEU A 257
ASP A 284
 None
 1.47A 3lslG-3wx7A:
undetectable		 3lslG-3wx7A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		4 / 8 ASN A 330
MET A 328
GLY A 351
GLN A 221
 None
None
CA  A 901 (-3.9A)
None
 0.97A 4af0A-3wx7A:
3.3		 4af0A-3wx7A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		4 / 7 PHE A 160
HIS A 223
ILE A 287
TYR A  31
 None
 1.04A 4g5jA-3wx7A:
undetectable		 4g5jA-3wx7A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 12 LEU A 257
ASP A 254
VAL A 286
PHE A 314
PHE A 325
 None
 1.17A 4iaqA-3wx7A:
undetectable		 4iaqA-3wx7A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 12 LEU A 257
ASP A 254
VAL A 286
PHE A 314
PHE A 325
 None
 1.20A 4iarA-3wx7A:
undetectable		 4iarA-3wx7A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 303
GLY A 298
ARG A 300
PHE A 293
ASP A  44
 None
 1.21A 4kicA-3wx7A:
undetectable		 4kicA-3wx7A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 12 ILE A  30
ALA A 318
VAL A  45
LEU A  32
LEU A 243
 None
 1.25A 4qynA-3wx7A:
undetectable		 4qynA-3wx7A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 12 ILE A  30
ALA A 318
VAL A  45
LEU A  32
LEU A 243
 None
 1.02A 4qzuC-3wx7A:
undetectable		 4qzuC-3wx7A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 12 HIS A  97
LEU A 163
THR A 166
VAL A 211
PRO A 128
 ZN  A 902 ( 3.3A)
None
None
None
None
 1.20A 4xiwB-3wx7A:
undetectable
4xiwE-3wx7A:
undetectable		 4xiwB-3wx7A:
18.25
4xiwE-3wx7A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_1
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		3 / 3 SER A  86
GLU A 292
GLU A  73
 None
 0.77A 4ymgB-3wx7A:
undetectable		 4ymgB-3wx7A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		4 / 6 ASP A 174
THR A 332
PRO A 333
VAL A 353
 None
None
GOL  A 904 (-4.6A)
None
 1.10A 4yoaA-3wx7A:
undetectable		 4yoaA-3wx7A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 12 TYR A  59
ALA A  56
PHE A 325
TYR A 331
ILE A 287
 None
 1.23A 5ljbA-3wx7A:
undetectable		 5ljbA-3wx7A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 12 TYR A  59
ALA A  56
PHE A 325
TYR A 331
ILE A 287
 None
 1.23A 5ljcA-3wx7A:
undetectable		 5ljcA-3wx7A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 6 ASP A  35
ASP A  36
HIS A  93
HIS A  97
HIS A 291
 ACT  A 903 (-3.5A)
ZN  A 902 ( 2.5A)
ZN  A 902 ( 3.4A)
ZN  A 902 ( 3.3A)
ACT  A 903 (-4.4A)
 0.37A 5ncdA-3wx7A:
16.3
5ncdD-3wx7A:
16.4		 5ncdA-3wx7A:
21.10
5ncdD-3wx7A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 6 ASP A  35
ASP A  36
HIS A  93
HIS A  97
HIS A 291
 ACT  A 903 (-3.5A)
ZN  A 902 ( 2.5A)
ZN  A 902 ( 3.4A)
ZN  A 902 ( 3.3A)
ACT  A 903 (-4.4A)
 0.32A 5ncdB-3wx7A:
16.2
5ncdC-3wx7A:
16.4		 5ncdB-3wx7A:
21.10
5ncdC-3wx7A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		4 / 4 ASP A  35
HIS A  93
HIS A  97
HIS A 291
 ACT  A 903 (-3.5A)
ZN  A 902 ( 3.4A)
ZN  A 902 ( 3.3A)
ACT  A 903 (-4.4A)
 0.24A 5ncdD-3wx7A:
16.4		 5ncdD-3wx7A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		6 / 8 ASP A  35
ASP A  36
HIS A  93
HIS A  97
PRO A 164
HIS A 291
 ACT  A 903 (-3.5A)
ZN  A 902 ( 2.5A)
ZN  A 902 ( 3.4A)
ZN  A 902 ( 3.3A)
ACT  A 903 (-4.3A)
ACT  A 903 (-4.4A)
 0.26A 5nekB-3wx7A:
16.4		 5nekB-3wx7A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		6 / 8 ASP A  35
ASP A  36
HIS A  93
HIS A  97
TRP A 225
HIS A 291
 ACT  A 903 (-3.5A)
ZN  A 902 ( 2.5A)
ZN  A 902 ( 3.4A)
ZN  A 902 ( 3.3A)
None
ACT  A 903 (-4.4A)
 0.32A 5nekD-3wx7A:
16.4		 5nekD-3wx7A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 6 ASP A  35
ASP A  36
HIS A  93
HIS A  97
HIS A 291
 ACT  A 903 (-3.5A)
ZN  A 902 ( 2.5A)
ZN  A 902 ( 3.4A)
ZN  A 902 ( 3.3A)
ACT  A 903 (-4.4A)
 0.36A 5nelA-3wx7A:
16.5
5nelD-3wx7A:
16.3		 5nelA-3wx7A:
21.10
5nelD-3wx7A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 6 ASP A  35
HIS A  93
HIS A  97
LEU A 289
HIS A 291
 ACT  A 903 (-3.5A)
ZN  A 902 ( 3.4A)
ZN  A 902 ( 3.3A)
None
ACT  A 903 (-4.4A)
 0.36A 5nelB-3wx7A:
16.2
5nelC-3wx7A:
16.5		 5nelB-3wx7A:
21.10
5nelC-3wx7A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_H_SAMH501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 10 LEU A  65
GLY A  67
GLY A  69
LEU A  80
ALA A  76
 None
 1.03A 5o96G-3wx7A:
2.9
5o96H-3wx7A:
2.8		 5o96G-3wx7A:
19.04
5o96H-3wx7A:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		3 / 3 HIS A  97
ASP A  36
HIS A 291
 ZN  A 902 ( 3.3A)
ZN  A 902 ( 2.5A)
ACT  A 903 (-4.4A)
 0.77A 5oexD-3wx7A:
undetectable		 5oexD-3wx7A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		3 / 3 SER A  94
HIS A  97
TYR A 165
 None
ZN  A 902 ( 3.3A)
None
 0.98A 5y2tA-3wx7A:
undetectable		 5y2tA-3wx7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 11 HIS A  64
ASN A  61
SER A  42
HIS A 291
PRO A 164
 None
None
None
ACT  A 903 (-4.4A)
ACT  A 903 (-4.3A)
 1.49A 5z0hA-3wx7A:
undetectable
5z0hB-3wx7A:
undetectable		 5z0hA-3wx7A:
11.90
5z0hB-3wx7A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 3wx7 CHITIN
OLIGOSACCHARIDE
DEACETYLASE
(Vibrio
parahaemolyticus) 		5 / 11 HIS A  64
ASN A  61
SER A  42
HIS A 291
PRO A 164
 None
None
None
ACT  A 903 (-4.4A)
ACT  A 903 (-4.3A)
 1.48A 5z0lA-3wx7A:
undetectable
5z0lB-3wx7A:
undetectable		 5z0lA-3wx7A:
11.90
5z0lB-3wx7A:
12.66