SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wxf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 12 LEU A 697
LEU A 695
LEU A 694
MET A 789
LEU A 729
 None
 1.27A 1a28B-3wxfA:
undetectable		 1a28B-3wxfA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_1
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 4 SER A 596
SER A 820
LEU A 795
PHE A 818
 None
 1.47A 1r5lA-3wxfA:
undetectable		 1r5lA-3wxfA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 12 LEU A 697
LEU A 695
LEU A 694
MET A 789
LEU A 729
 None
 1.19A 1sqnA-3wxfA:
undetectable		 1sqnA-3wxfA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 10 ARG A 644
THR A 881
MET A 882
GLY A 809
VAL A 611
 None
 1.46A 2coiA-3wxfA:
undetectable
2coiB-3wxfA:
undetectable		 2coiA-3wxfA:
22.22
2coiB-3wxfA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COI_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 10 VAL A 611
ARG A 644
THR A 881
MET A 882
GLY A 809
 None
 1.47A 2coiA-3wxfA:
undetectable
2coiB-3wxfA:
undetectable		 2coiA-3wxfA:
22.22
2coiB-3wxfA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 11 ARG A 644
THR A 881
MET A 882
GLY A 809
VAL A 611
 None
 1.45A 2cojA-3wxfA:
undetectable
2cojB-3wxfA:
undetectable		 2cojA-3wxfA:
22.22
2cojB-3wxfA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_B_GBNB420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 9 VAL A 611
ARG A 644
THR A 881
MET A 882
GLY A 809
 None
 1.45A 2cojA-3wxfA:
undetectable
2cojB-3wxfA:
undetectable		 2cojA-3wxfA:
22.22
2cojB-3wxfA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 12 LEU A 697
LEU A 695
LEU A 694
MET A 789
LEU A 729
 None
 1.19A 2w8yB-3wxfA:
undetectable		 2w8yB-3wxfA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 12 LEU A 697
LEU A 695
LEU A 694
MET A 789
LEU A 729
 None
 1.23A 3d90A-3wxfA:
undetectable		 3d90A-3wxfA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		3 / 3 MET A 874
MET A 714
PHE A 709
 None
 1.18A 3gn8A-3wxfA:
undetectable		 3gn8A-3wxfA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 8 LEU A 612
LEU A 694
CYH A 746
SER A 879
 None
 0.98A 3lm8A-3wxfA:
undetectable
3lm8C-3wxfA:
undetectable		 3lm8A-3wxfA:
19.57
3lm8C-3wxfA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 12 CYH A 604
LEU A 605
LEU A 795
ALA A 804
ILE A 589
 None
 1.19A 4x1kD-3wxfA:
undetectable		 4x1kD-3wxfA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 6 VAL A 691
LEU A 747
ILE A 772
PHE A 740
 None
 0.82A 5jw1A-3wxfA:
undetectable		 5jw1A-3wxfA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 8 THR A 724
PRO A 766
VAL A 842
GLY A 843
 None
 1.02A 5nzyA-3wxfA:
undetectable		 5nzyA-3wxfA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wxf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		3 / 3 ASN A 860
VAL A 722
HIS A 854
 None
 0.88A 6a5yD-3wxfA:
undetectable		 6a5yD-3wxfA:
14.38