SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wxr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
(Saccharomyces
cerevisiae) 		4 / 8 GLY K 104
HIS K  40
THR K  41
ILE K 103
 None
 0.82A 1c9sU-3wxrK:
undetectable
1c9sV-3wxrK:
undetectable		 1c9sU-3wxrK:
14.29
1c9sV-3wxrK:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
(Saccharomyces
cerevisiae) 		4 / 8 LEU K 167
VAL K 178
GLY K 177
LEU K   4
 None
 0.85A 1jlbA-3wxrK:
undetectable		 1jlbA-3wxrK:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 4 ILE L 101
LEU L  83
VAL L  87
ALA L  93
 None
 1.00A 1mz9A-3wxrL:
undetectable		 1mz9A-3wxrL:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
(Saccharomyces
cerevisiae) 		4 / 8 LEU K 167
VAL K 178
GLY K 177
LEU K   4
 None
 0.92A 1s1xA-3wxrK:
undetectable		 1s1xA-3wxrK:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.72A 2f162-3wxrL:
28.7		 2f162-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
ALA L  27
LYS L  33
ALA L  49
 None
 0.75A 2f162-3wxrL:
28.7		 2f162-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   2
THR L   1
SER L 174
GLY L 173
ALA L 165
 None
 0.94A 2f162-3wxrL:
28.7		 2f162-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR L   1
ALA L  27
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.60A 2f16H-3wxrL:
28.8
2f16I-3wxrL:
25.4		 2f16H-3wxrL:
29.57
2f16I-3wxrL:
22.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 10 ALA L  20
ALA L  22
ALA L  27
VAL L  31
LYS L  33
GLY L  48
 None
 0.83A 2f16K-3wxrL:
37.8
2f16L-3wxrL:
23.2		 2f16K-3wxrL:
100.00
2f16L-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		9 / 10 THR L   1
ALA L  20
THR L  21
ALA L  22
ALA L  27
VAL L  31
LYS L  33
GLY L  47
ALA L  49
 None
 0.65A 2f16K-3wxrL:
37.8
2f16L-3wxrL:
23.2		 2f16K-3wxrL:
100.00
2f16L-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR L   1
THR L  21
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.79A 2f16N-3wxrL:
28.7		 2f16N-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   2
THR L   1
SER L 174
GLY L 173
ALA L 165
 None
 0.94A 2f16N-3wxrL:
28.7		 2f16N-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR L   1
ALA L  27
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.61A 2f16V-3wxrL:
28.8
2f16W-3wxrL:
25.4		 2f16V-3wxrL:
29.57
2f16W-3wxrL:
22.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 10 ALA L  20
ALA L  22
ALA L  27
VAL L  31
LYS L  33
GLY L  48
 None
 0.84A 2f16Y-3wxrL:
37.8
2f16Z-3wxrL:
23.0		 2f16Y-3wxrL:
100.00
2f16Z-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		9 / 10 THR L   1
ALA L  20
THR L  21
ALA L  22
ALA L  27
VAL L  31
LYS L  33
GLY L  47
ALA L  49
 None
 0.65A 2f16Y-3wxrL:
37.8
2f16Z-3wxrL:
23.0		 2f16Y-3wxrL:
100.00
2f16Z-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 THR L 120
ASP K   1
SER K  16
 None
 0.84A 2nxeA-3wxrL:
undetectable		 2nxeA-3wxrL:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
(Saccharomyces
cerevisiae) 		5 / 11 ILE K  59
LEU K  37
ILE K 103
VAL K  99
LEU K  87
 None
 1.22A 3a51A-3wxrK:
undetectable		 3a51A-3wxrK:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_1
(RENIN)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
(Saccharomyces
cerevisiae) 		5 / 12 GLN K 190
GLY K   5
THR K  34
VAL K 178
LEU K 115
 None
 1.13A 3d91B-3wxrK:
undetectable		 3d91B-3wxrK:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		5 / 10 ALA G 202
ASP G 205
GLY G 165
ALA G  48
ILE G 199
 None
 1.00A 3ekwA-3wxrG:
undetectable		 3ekwA-3wxrG:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 7 ILE G 199
GLY G 167
VAL G  76
LEU G  52
 None
 0.92A 3elzA-3wxrG:
2.6		 3elzA-3wxrG:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
(Saccharomyces
cerevisiae) 		4 / 7 LEU K 143
TYR K 129
ILE K   3
ARG K  84
 None
 1.22A 3ik3A-3wxrK:
undetectable		 3ik3A-3wxrK:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
(Saccharomyces
cerevisiae) 		4 / 7 LEU K 143
TYR K 129
ILE K   3
ARG K  84
 None
 1.25A 3ik3B-3wxrK:
undetectable		 3ik3B-3wxrK:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 4 ARG G  92
ASP G 113
GLY G 154
THR G 135
 None
 1.29A 3k4vB-3wxrG:
undetectable		 3k4vB-3wxrG:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 SER L 131
ALA L 136
ASP L 141
LEU L 140
LYS L   1
 None
 1.30A 3lcvB-3wxrL:
undetectable		 3lcvB-3wxrL:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 12 THR L   1
THR L  21
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.79A 3mg02-3wxrL:
28.6
3mg0V-3wxrL:
28.9		 3mg02-3wxrL:
24.20
3mg0V-3wxrL:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   2
THR L   1
SER L 174
GLY L 173
ALA L 165
 None
 0.92A 3mg02-3wxrL:
28.6
3mg0V-3wxrL:
28.9		 3mg02-3wxrL:
24.20
3mg0V-3wxrL:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.40A 3mg0H-3wxrL:
28.8
3mg0I-3wxrL:
25.4		 3mg0H-3wxrL:
29.57
3mg0I-3wxrL:
22.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 ALA L  20
ALA L  27
VAL L  31
LYS L  33
GLY L  48
 None
 0.77A 3mg0K-3wxrL:
37.8
3mg0L-3wxrL:
23.3		 3mg0K-3wxrL:
100.00
3mg0L-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		9 / 11 THR L   1
ALA L  20
ALA L  27
VAL L  31
LYS L  33
ALA L  46
GLY L  47
ALA L  49
SER L 131
 None
 0.68A 3mg0K-3wxrL:
37.8
3mg0L-3wxrL:
23.3		 3mg0K-3wxrL:
100.00
3mg0L-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		9 / 11 THR L   1
ALA L  20
THR L  21
ALA L  27
VAL L  31
LYS L  33
ALA L  46
ALA L  49
SER L 131
 None
 0.60A 3mg0K-3wxrL:
37.8
3mg0L-3wxrL:
23.3		 3mg0K-3wxrL:
100.00
3mg0L-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  22
ALA L  46
GLY L  47
SER L 131
 None
 0.94A 3mg0K-3wxrL:
37.8
3mg0L-3wxrL:
23.3		 3mg0K-3wxrL:
100.00
3mg0L-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR L   1
THR L  21
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.78A 3mg0N-3wxrL:
28.6		 3mg0N-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   2
THR L   1
SER L 174
GLY L 173
ALA L 165
 None
 0.89A 3mg0N-3wxrL:
28.6		 3mg0N-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR L   1
ALA L  27
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.67A 3mg0V-3wxrL:
28.9
3mg0W-3wxrL:
25.3		 3mg0V-3wxrL:
29.57
3mg0W-3wxrL:
22.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 12 ALA L  20
ALA L  22
ALA L  27
VAL L  31
LYS L  33
GLY L  48
 None
 0.83A 3mg0Y-3wxrL:
23.1
3mg0Z-3wxrL:
22.9		 3mg0Y-3wxrL:
100.00
3mg0Z-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		11 / 12 THR L   1
ALA L  20
THR L  21
ALA L  22
ALA L  27
VAL L  31
LYS L  33
ALA L  46
GLY L  47
ALA L  49
SER L 131
 None
 0.65A 3mg0Y-3wxrL:
23.1
3mg0Z-3wxrL:
22.9		 3mg0Y-3wxrL:
100.00
3mg0Z-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 12 THR L   1
THR L  21
ALA L  22
ALA L  46
GLY L  47
SER L 131
 None
 1.43A 3mg0Y-3wxrL:
23.1
3mg0Z-3wxrL:
22.9		 3mg0Y-3wxrL:
100.00
3mg0Z-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 8 SER L  18
ARG L  19
ALA L 164
ALA L 165
 None
 1.00A 3ns1L-3wxrL:
undetectable		 3ns1L-3wxrL:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
(Saccharomyces
cerevisiae) 		4 / 5 GLY K 105
GLU K 114
GLY K 104
PRO K  76
 None
 1.05A 3onnA-3wxrK:
undetectable		 3onnA-3wxrK:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 7 VAL G  76
GLY G  38
ILE G  39
VAL G 230
 None
 0.83A 3ufnB-3wxrG:
undetectable		 3ufnB-3wxrG:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		5 / 12 PHE G 137
LEU G  87
GLY G  91
ILE G  73
VAL G  69
 None
 1.03A 4a6dA-3wxrG:
undetectable		 4a6dA-3wxrG:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		5 / 12 PHE G 137
LEU G  87
GLY G  91
ILE G  73
VAL G  69
 None
 1.10A 4a6eA-3wxrG:
undetectable		 4a6eA-3wxrG:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
(Saccharomyces
cerevisiae) 		3 / 3 GLN K 190
ASP K 193
GLN K 197
 None
 0.78A 4aztA-3wxrK:
undetectable		 4aztA-3wxrK:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 5 GLY G  74
ILE G  66
VAL G  45
SER G 216
 None
 1.07A 4d33A-3wxrG:
undetectable		 4d33A-3wxrG:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 5 GLY G  74
ILE G  66
VAL G  45
SER G 216
 None
 1.05A 4d33B-3wxrG:
undetectable		 4d33B-3wxrG:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 6 GLY G  74
ILE G  66
VAL G  45
SER G 216
 None
 1.08A 4d39B-3wxrG:
undetectable		 4d39B-3wxrG:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 6 LEU G  87
LEU G 115
GLU G  94
TYR G 118
 None
 1.20A 4f3tA-3wxrG:
2.3		 4f3tA-3wxrG:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
(Saccharomyces
cerevisiae) 		4 / 8 ARG K  35
PHE K  45
GLN K  54
GLY K  50
 None
 0.99A 4k87A-3wxrK:
undetectable		 4k87A-3wxrK:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.72A 4qvlV-3wxrL:
28.9
4qvlb-3wxrL:
28.7		 4qvlV-3wxrL:
29.29
4qvlb-3wxrL:
24.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 11 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.69A 4qvlK-3wxrL:
38.3
4qvlL-3wxrL:
23.4		 4qvlK-3wxrL:
100.00
4qvlL-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.94A 4qvlK-3wxrL:
38.3
4qvlL-3wxrL:
23.4		 4qvlK-3wxrL:
100.00
4qvlL-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.72A 4qvlH-3wxrL:
27.2
4qvlN-3wxrL:
28.8		 4qvlH-3wxrL:
29.29
4qvlN-3wxrL:
24.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 11 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.69A 4qvlY-3wxrL:
38.3
4qvlZ-3wxrL:
23.2		 4qvlY-3wxrL:
100.00
4qvlZ-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.93A 4qvlY-3wxrL:
38.3
4qvlZ-3wxrL:
23.2		 4qvlY-3wxrL:
100.00
4qvlZ-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.74A 4qvmV-3wxrL:
28.9
4qvmb-3wxrL:
28.7		 4qvmV-3wxrL:
29.29
4qvmb-3wxrL:
24.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 9 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.68A 4qvmK-3wxrL:
37.9
4qvmL-3wxrL:
23.3		 4qvmK-3wxrL:
99.53
4qvmL-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 9 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.91A 4qvmK-3wxrL:
37.9
4qvmL-3wxrL:
23.3		 4qvmK-3wxrL:
99.53
4qvmL-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.74A 4qvmH-3wxrL:
27.3
4qvmN-3wxrL:
28.7		 4qvmH-3wxrL:
29.29
4qvmN-3wxrL:
24.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.69A 4qvmY-3wxrL:
37.9
4qvmZ-3wxrL:
23.0		 4qvmY-3wxrL:
99.53
4qvmZ-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.91A 4qvmY-3wxrL:
37.9
4qvmZ-3wxrL:
23.0		 4qvmY-3wxrL:
99.53
4qvmZ-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.67A 4qvnV-3wxrL:
28.8
4qvnb-3wxrL:
28.7		 4qvnV-3wxrL:
29.29
4qvnb-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
THR L  21
ALA L  27
LYS L  33
ALA L  49
 None
 0.72A 4qvnV-3wxrL:
28.8
4qvnb-3wxrL:
28.7		 4qvnV-3wxrL:
29.29
4qvnb-3wxrL:
24.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 9 THR L   1
ALA L  20
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.67A 4qvnK-3wxrL:
38.0
4qvnL-3wxrL:
23.3		 4qvnK-3wxrL:
99.53
4qvnL-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 9 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
ALA L  49
 None
 0.58A 4qvnK-3wxrL:
38.0
4qvnL-3wxrL:
23.3		 4qvnK-3wxrL:
99.53
4qvnL-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.66A 4qvnH-3wxrL:
27.2
4qvnN-3wxrL:
28.7		 4qvnH-3wxrL:
29.29
4qvnN-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
THR L  21
ALA L  27
LYS L  33
ALA L  49
 None
 0.71A 4qvnH-3wxrL:
27.2
4qvnN-3wxrL:
28.7		 4qvnH-3wxrL:
29.29
4qvnN-3wxrL:
24.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 9 THR L   1
ALA L  20
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.67A 4qvnY-3wxrL:
38.0
4qvnZ-3wxrL:
23.1		 4qvnY-3wxrL:
99.53
4qvnZ-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 9 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
ALA L  49
 None
 0.57A 4qvnY-3wxrL:
38.0
4qvnZ-3wxrL:
23.1		 4qvnY-3wxrL:
99.53
4qvnZ-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.45A 4qvpH-3wxrL:
27.2
4qvpI-3wxrL:
25.3		 4qvpH-3wxrL:
29.29
4qvpI-3wxrL:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.72A 4qvpK-3wxrL:
38.0
4qvpL-3wxrL:
23.0		 4qvpK-3wxrL:
99.53
4qvpL-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.91A 4qvpK-3wxrL:
38.0
4qvpL-3wxrL:
23.0		 4qvpK-3wxrL:
99.53
4qvpL-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.45A 4qvpV-3wxrL:
28.8
4qvpW-3wxrL:
25.4		 4qvpV-3wxrL:
29.29
4qvpW-3wxrL:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.72A 4qvpY-3wxrL:
38.0
4qvpZ-3wxrL:
23.1		 4qvpY-3wxrL:
99.53
4qvpZ-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.90A 4qvpY-3wxrL:
38.0
4qvpZ-3wxrL:
23.1		 4qvpY-3wxrL:
99.53
4qvpZ-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 9 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.71A 4qvqK-3wxrL:
37.6
4qvqL-3wxrL:
23.3		 4qvqK-3wxrL:
99.53
4qvqL-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 9 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.70A 4qvqY-3wxrL:
37.6
4qvqZ-3wxrL:
23.0		 4qvqY-3wxrL:
99.53
4qvqZ-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.45A 4qvvH-3wxrL:
27.3		 4qvvH-3wxrL:
29.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
ALA L  46
ALA L  49
 None
 0.74A 4qvvH-3wxrL:
27.3		 4qvvH-3wxrL:
29.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 8 THR L   1
LYS L  33
GLY L  47
GLY L  48
 None
 0.42A 4qvvK-3wxrL:
38.2
4qvvL-3wxrL:
23.2		 4qvvK-3wxrL:
99.53
4qvvL-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.44A 4qvvV-3wxrL:
28.9		 4qvvV-3wxrL:
29.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 8 THR L   1
LYS L  33
GLY L  47
GLY L  48
 None
 0.42A 4qvvY-3wxrL:
38.2
4qvvZ-3wxrL:
23.0		 4qvvY-3wxrL:
99.53
4qvvZ-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.72A 4qvwV-3wxrL:
28.9
4qvwb-3wxrL:
28.8		 4qvwV-3wxrL:
29.29
4qvwb-3wxrL:
24.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
GLY L  48
 None
 0.66A 4qvwK-3wxrL:
38.3
4qvwL-3wxrL:
23.3		 4qvwK-3wxrL:
99.53
4qvwL-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.92A 4qvwK-3wxrL:
38.3
4qvwL-3wxrL:
23.3		 4qvwK-3wxrL:
99.53
4qvwL-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.71A 4qvwH-3wxrL:
27.2
4qvwN-3wxrL:
28.7		 4qvwH-3wxrL:
29.29
4qvwN-3wxrL:
24.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
GLY L  48
 None
 0.66A 4qvwY-3wxrL:
38.4
4qvwZ-3wxrL:
23.1		 4qvwY-3wxrL:
99.53
4qvwZ-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.91A 4qvwY-3wxrL:
38.4
4qvwZ-3wxrL:
23.1		 4qvwY-3wxrL:
99.53
4qvwZ-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.42A 4qvyH-3wxrL:
27.2		 4qvyH-3wxrL:
29.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR L   1
ALA L  20
THR L  21
ALA L  22
ALA L  27
VAL L  31
LYS L  33
GLY L  48
 None
 0.52A 4qvyK-3wxrL:
38.7
4qvyL-3wxrL:
23.3		 4qvyK-3wxrL:
99.53
4qvyL-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 10 THR L   1
ALA L  20
THR L  21
VAL L  31
LYS L  33
GLY L  47
 None
 0.95A 4qvyK-3wxrL:
38.7
4qvyL-3wxrL:
23.3		 4qvyK-3wxrL:
99.53
4qvyL-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.42A 4qvyV-3wxrL:
28.9
4qvyW-3wxrL:
25.4		 4qvyV-3wxrL:
29.29
4qvyW-3wxrL:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR L   1
ALA L  20
THR L  21
ALA L  22
ALA L  27
VAL L  31
LYS L  33
GLY L  48
 None
 0.51A 4qvyY-3wxrL:
38.7
4qvyZ-3wxrL:
23.1		 4qvyY-3wxrL:
99.53
4qvyZ-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 10 THR L   1
ALA L  20
THR L  21
VAL L  31
LYS L  33
GLY L  47
 None
 0.95A 4qvyY-3wxrL:
38.7
4qvyZ-3wxrL:
23.1		 4qvyY-3wxrL:
99.53
4qvyZ-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.72A 4qw0V-3wxrL:
28.9
4qw0b-3wxrL:
28.8		 4qw0V-3wxrL:
29.29
4qw0b-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.44A 4qw0H-3wxrL:
27.2
4qw0I-3wxrL:
25.2		 4qw0H-3wxrL:
29.29
4qw0I-3wxrL:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 7 THR L   1
ALA L  20
THR L  21
ALA L  22
LYS L  33
 None
 0.26A 4qw0K-3wxrL:
38.6		 4qw0K-3wxrL:
99.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.71A 4qw0H-3wxrL:
27.2
4qw0N-3wxrL:
28.7		 4qw0H-3wxrL:
29.29
4qw0N-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.44A 4qw0V-3wxrL:
28.9
4qw0W-3wxrL:
25.3		 4qw0V-3wxrL:
29.29
4qw0W-3wxrL:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 7 THR L   1
ALA L  20
THR L  21
ALA L  22
LYS L  33
 None
 0.27A 4qw0Y-3wxrL:
30.2		 4qw0Y-3wxrL:
99.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.45A 4qw1H-3wxrL:
27.2
4qw1I-3wxrL:
25.4		 4qw1H-3wxrL:
29.29
4qw1I-3wxrL:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR L   1
ALA L  20
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.64A 4qw1K-3wxrL:
38.4
4qw1L-3wxrL:
23.4		 4qw1K-3wxrL:
99.53
4qw1L-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.69A 4qw1K-3wxrL:
38.4
4qw1L-3wxrL:
23.4		 4qw1K-3wxrL:
99.53
4qw1L-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.92A 4qw1K-3wxrL:
38.4
4qw1L-3wxrL:
23.4		 4qw1K-3wxrL:
99.53
4qw1L-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.45A 4qw1V-3wxrL:
28.8
4qw1W-3wxrL:
25.4		 4qw1V-3wxrL:
29.29
4qw1W-3wxrL:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 10 THR L   1
ALA L  20
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.64A 4qw1Y-3wxrL:
38.4
4qw1Z-3wxrL:
23.1		 4qw1Y-3wxrL:
99.53
4qw1Z-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 10 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.69A 4qw1Y-3wxrL:
38.4
4qw1Z-3wxrL:
23.1		 4qw1Y-3wxrL:
99.53
4qw1Z-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.92A 4qw1Y-3wxrL:
38.4
4qw1Z-3wxrL:
23.1		 4qw1Y-3wxrL:
99.53
4qw1Z-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.73A 4qw3V-3wxrL:
28.9
4qw3b-3wxrL:
28.7		 4qw3V-3wxrL:
29.29
4qw3b-3wxrL:
24.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.68A 4qw3K-3wxrL:
37.6
4qw3L-3wxrL:
23.2		 4qw3K-3wxrL:
99.53
4qw3L-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.92A 4qw3K-3wxrL:
37.6
4qw3L-3wxrL:
23.2		 4qw3K-3wxrL:
99.53
4qw3L-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.73A 4qw3H-3wxrL:
27.2
4qw3N-3wxrL:
28.7		 4qw3H-3wxrL:
29.29
4qw3N-3wxrL:
24.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 10 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.68A 4qw3Y-3wxrL:
37.6
4qw3Z-3wxrL:
22.9		 4qw3Y-3wxrL:
99.53
4qw3Z-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.92A 4qw3Y-3wxrL:
37.6
4qw3Z-3wxrL:
22.9		 4qw3Y-3wxrL:
99.53
4qw3Z-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 9 THR L   1
ALA L  20
ALA L  27
LYS L  33
GLY L  47
 None
 0.55A 4qwuK-3wxrL:
37.8
4qwuL-3wxrL:
23.2		 4qwuK-3wxrL:
99.53
4qwuL-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 9 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
 None
 0.26A 4qwuK-3wxrL:
37.8
4qwuL-3wxrL:
23.2		 4qwuK-3wxrL:
99.53
4qwuL-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 9 THR L   1
ALA L  20
ALA L  27
LYS L  33
GLY L  47
 None
 0.62A 4qwuY-3wxrL:
37.8
4qwuZ-3wxrL:
23.2		 4qwuY-3wxrL:
99.53
4qwuZ-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 9 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
 None
 0.27A 4qwuY-3wxrL:
37.8
4qwuZ-3wxrL:
23.2		 4qwuY-3wxrL:
99.53
4qwuZ-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
(Saccharomyces
cerevisiae) 		5 / 12 GLN K  85
PHE K  82
GLU K  86
LEU K  74
TYR K  58
 None
 1.44A 4r7lA-3wxrK:
undetectable		 4r7lA-3wxrK:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
(Saccharomyces
cerevisiae) 		3 / 3 MET K 151
GLU K 155
LEU K 159
 None
 0.57A 4v2oB-3wxrK:
undetectable		 4v2oB-3wxrK:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 5 ARG G  85
ARG G  90
GLY G  91
GLU G  94
 None
 1.16A 4z3oA-3wxrG:
undetectable
4z3oB-3wxrG:
undetectable		 4z3oA-3wxrG:
17.90
4z3oB-3wxrG:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 6 ARG G  90
GLY G  91
GLU G  94
ARG G  85
 None
 1.09A 5btaA-3wxrG:
undetectable
5btaB-3wxrG:
undetectable
5btaC-3wxrG:
undetectable		 5btaA-3wxrG:
20.42
5btaB-3wxrG:
21.88
5btaC-3wxrG:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 6 ARG G  85
ARG G  90
GLY G  91
GLU G  94
 None
 1.07A 5btcA-3wxrG:
undetectable
5btcC-3wxrG:
undetectable
5btcD-3wxrG:
undetectable		 5btcA-3wxrG:
20.42
5btcC-3wxrG:
20.42
5btcD-3wxrG:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 6 ARG G  90
GLY G  91
GLU G  94
ARG G  85
 None
 1.06A 5btcA-3wxrG:
undetectable
5btcB-3wxrG:
undetectable
5btcC-3wxrG:
undetectable		 5btcA-3wxrG:
20.42
5btcB-3wxrG:
21.88
5btcC-3wxrG:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.73A 5bxnV-3wxrL:
28.7
5bxnb-3wxrL:
28.7		 5bxnV-3wxrL:
28.87
5bxnb-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.44A 5bxnH-3wxrL:
28.7
5bxnI-3wxrL:
25.5		 5bxnH-3wxrL:
28.87
5bxnI-3wxrL:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 11 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.69A 5bxnK-3wxrL:
38.1
5bxnL-3wxrL:
23.1		 5bxnK-3wxrL:
100.00
5bxnL-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.92A 5bxnK-3wxrL:
38.1
5bxnL-3wxrL:
23.1		 5bxnK-3wxrL:
100.00
5bxnL-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.73A 5bxnH-3wxrL:
28.7
5bxnN-3wxrL:
28.8		 5bxnH-3wxrL:
28.87
5bxnN-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.41A 5bxnV-3wxrL:
28.7
5bxnW-3wxrL:
25.5		 5bxnV-3wxrL:
28.87
5bxnW-3wxrL:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 11 THR L   1
ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.70A 5bxnY-3wxrL:
38.1
5bxnZ-3wxrL:
23.1		 5bxnY-3wxrL:
100.00
5bxnZ-3wxrL:
22.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.92A 5bxnY-3wxrL:
38.1
5bxnZ-3wxrL:
23.1		 5bxnY-3wxrL:
100.00
5bxnZ-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 5 ARG G  90
GLY G  91
GLU G  94
ARG G  85
 None
 1.18A 5cdqA-3wxrG:
undetectable
5cdqB-3wxrG:
undetectable
5cdqC-3wxrG:
undetectable		 5cdqA-3wxrG:
21.99
5cdqB-3wxrG:
23.42
5cdqC-3wxrG:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.44A 5cz7V-3wxrL:
28.9
5cz7W-3wxrL:
25.4		 5cz7V-3wxrL:
29.29
5cz7W-3wxrL:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.72A 5d0xV-3wxrL:
28.9
5d0xb-3wxrL:
28.7		 5d0xV-3wxrL:
29.29
5d0xb-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
THR L  21
LYS L  33
ALA L  46
ALA L  49
 None
 0.72A 5d0xH-3wxrL:
27.2
5d0xI-3wxrL:
25.2		 5d0xH-3wxrL:
29.29
5d0xI-3wxrL:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 9 ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.72A 5d0xK-3wxrL:
37.9
5d0xL-3wxrL:
23.3		 5d0xK-3wxrL:
75.44
5d0xL-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.72A 5d0xH-3wxrL:
27.2
5d0xN-3wxrL:
28.7		 5d0xH-3wxrL:
29.29
5d0xN-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.42A 5d0xV-3wxrL:
28.9		 5d0xV-3wxrL:
29.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
THR L  21
LYS L  33
ALA L  46
ALA L  49
 None
 0.72A 5d0xV-3wxrL:
28.9		 5d0xV-3wxrL:
29.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 9 ALA L  20
THR L  21
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.72A 5d0xY-3wxrL:
38.0
5d0xZ-3wxrL:
23.0		 5d0xY-3wxrL:
75.44
5d0xZ-3wxrL:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 LEU L  59
THR L  99
GLY L  43
ILE L 101
GLY L 130
 None
 0.97A 5d4uC-3wxrL:
undetectable		 5d4uC-3wxrL:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 LEU L  59
THR L  99
GLY L  43
ILE L 101
GLY L 130
 None
 0.93A 5d4uD-3wxrL:
undetectable		 5d4uD-3wxrL:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 4 LEU L  42
ILE L  12
GLY L  43
ILE L 112
 None
 0.81A 5dzk3-3wxrL:
undetectable
5dzkm-3wxrL:
undetectable		 5dzk3-3wxrL:
1.71
5dzkm-3wxrL:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 5 ILE L  12
GLY L  43
ILE L 112
LEU L  42
 None
 0.75A 5dzkB-3wxrL:
undetectable
5dzkI-3wxrL:
undetectable
5dzkW-3wxrL:
undetectable		 5dzkB-3wxrL:
22.96
5dzkI-3wxrL:
20.20
5dzkW-3wxrL:
1.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 5 ILE L  12
GLY L  43
ILE L 112
LEU L  42
 None
 0.73A 5dzki-3wxrL:
undetectable
5dzkj-3wxrL:
undetectable
5dzkx-3wxrL:
undetectable		 5dzki-3wxrL:
20.20
5dzkj-3wxrL:
20.20
5dzkx-3wxrL:
1.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 5 ILE L  12
GLY L  43
ILE L 112
LEU L  42
 None
 0.78A 5dzkd-3wxrL:
undetectable
5dzkk-3wxrL:
undetectable
5dzky-3wxrL:
undetectable		 5dzkd-3wxrL:
22.96
5dzkk-3wxrL:
20.20
5dzky-3wxrL:
1.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 4 ILE L  12
GLY L  43
ILE L 112
LEU L  42
 None
 0.78A 5dzkl-3wxrL:
undetectable
5dzkz-3wxrL:
undetectable		 5dzkl-3wxrL:
20.20
5dzkz-3wxrL:
1.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_B_010B607_0
(HNL ISOENZYME 5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 ALA L 163
ALA L 165
VAL L 193
LEU L   4
VAL L 175
 None
 1.40A 5eb5B-3wxrL:
undetectable		 5eb5B-3wxrL:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		4 / 4 VAL L  76
GLU L 108
GLY L 103
LEU L  41
 None
 1.33A 5g5gC-3wxrL:
undetectable		 5g5gC-3wxrL:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.42A 5l5fH-3wxrL:
27.2
5l5fI-3wxrL:
25.4		 5l5fH-3wxrL:
29.29
5l5fI-3wxrL:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.42A 5l5fV-3wxrL:
28.9
5l5fW-3wxrL:
25.4		 5l5fV-3wxrL:
29.29
5l5fW-3wxrL:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.74A 5l5zV-3wxrL:
29.0
5l5zb-3wxrL:
28.7		 5l5zV-3wxrL:
29.29
5l5zb-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   2
THR L   1
SER L 174
GLY L 173
ALA L 165
 None
 0.92A 5l5zV-3wxrL:
29.0
5l5zb-3wxrL:
28.7		 5l5zV-3wxrL:
29.29
5l5zb-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.42A 5l5zH-3wxrL:
27.3
5l5zI-3wxrL:
25.5		 5l5zH-3wxrL:
29.29
5l5zI-3wxrL:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 9 ALA L  20
ALA L  22
ALA L  27
LYS L  33
GLY L  48
 None
 0.80A 5l5zK-3wxrL:
37.7
5l5zL-3wxrL:
23.1		 5l5zK-3wxrL:
82.55
5l5zL-3wxrL:
21.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 9 THR L   1
ALA L  20
THR L  21
ALA L  22
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.59A 5l5zK-3wxrL:
37.7
5l5zL-3wxrL:
23.1		 5l5zK-3wxrL:
82.55
5l5zL-3wxrL:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.74A 5l5zH-3wxrL:
27.3
5l5zN-3wxrL:
28.7		 5l5zH-3wxrL:
29.29
5l5zN-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   2
THR L   1
SER L 174
GLY L 173
ALA L 165
 None
 0.92A 5l5zH-3wxrL:
27.3
5l5zN-3wxrL:
28.7		 5l5zH-3wxrL:
29.29
5l5zN-3wxrL:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.42A 5l5zV-3wxrL:
29.0
5l5zW-3wxrL:
25.5		 5l5zV-3wxrL:
29.29
5l5zW-3wxrL:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 9 ALA L  20
ALA L  22
ALA L  27
LYS L  33
GLY L  48
 None
 0.80A 5l5zY-3wxrL:
37.7
5l5zZ-3wxrL:
23.1		 5l5zY-3wxrL:
82.55
5l5zZ-3wxrL:
21.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 9 THR L   1
ALA L  20
THR L  21
ALA L  22
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.59A 5l5zY-3wxrL:
37.7
5l5zZ-3wxrL:
23.1		 5l5zY-3wxrL:
82.55
5l5zZ-3wxrL:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.43A 5l66H-3wxrL:
27.2
5l66I-3wxrL:
25.5		 5l66H-3wxrL:
29.29
5l66I-3wxrL:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 10 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.63A 5l66K-3wxrL:
37.2
5l66L-3wxrL:
23.4		 5l66K-3wxrL:
77.83
5l66L-3wxrL:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.43A 5l66V-3wxrL:
28.9
5l66W-3wxrL:
25.4		 5l66V-3wxrL:
29.29
5l66W-3wxrL:
22.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 10 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
ALA L  49
 None
 0.63A 5l66Y-3wxrL:
37.1
5l66Z-3wxrL:
23.1		 5l66Y-3wxrL:
77.83
5l66Z-3wxrL:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   2
THR L   1
SER L 174
GLY L 173
ALA L 165
 None
 0.93A 5lf3b-3wxrL:
28.5		 5lf3b-3wxrL:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 THR L   1
ALA L  20
ALA L  46
GLY L  47
ALA L  49
 None
 0.64A 5lf3H-3wxrL:
29.8
5lf3I-3wxrL:
25.2		 5lf3H-3wxrL:
28.09
5lf3I-3wxrL:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 10 THR L   1
ALA L  20
THR L  21
ALA L  46
ALA L  49
 None
 0.79A 5lf3H-3wxrL:
29.8
5lf3I-3wxrL:
25.2		 5lf3H-3wxrL:
28.09
5lf3I-3wxrL:
23.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 11 THR L   1
ALA L  20
ALA L  22
LYS L  33
GLY L  47
GLY L  48
ALA L  49
TYR L 170
 None
 0.77A 5lf3K-3wxrL:
35.0
5lf3L-3wxrL:
24.2		 5lf3K-3wxrL:
65.38
5lf3L-3wxrL:
24.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR L   1
ALA L  20
THR L  21
ALA L  22
LYS L  33
ALA L  49
TYR L 170
 None
 0.53A 5lf3K-3wxrL:
35.0
5lf3L-3wxrL:
24.2		 5lf3K-3wxrL:
65.38
5lf3L-3wxrL:
24.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
TYR L 170
 None
 0.91A 5lf3K-3wxrL:
35.0
5lf3L-3wxrL:
24.2		 5lf3K-3wxrL:
65.38
5lf3L-3wxrL:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   2
THR L   1
SER L 174
GLY L 173
ALA L 165
 None
 0.93A 5lf3N-3wxrL:
28.5		 5lf3N-3wxrL:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 10 THR L   1
ALA L  20
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.58A 5lf3V-3wxrL:
29.8
5lf3W-3wxrL:
25.2		 5lf3V-3wxrL:
28.09
5lf3W-3wxrL:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 10 THR L   1
ALA L  20
THR L  21
LYS L  33
ALA L  46
ALA L  49
 None
 0.72A 5lf3V-3wxrL:
29.8
5lf3W-3wxrL:
25.2		 5lf3V-3wxrL:
28.09
5lf3W-3wxrL:
23.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 11 THR L   1
ALA L  20
ALA L  22
LYS L  33
GLY L  47
GLY L  48
ALA L  49
TYR L 170
 None
 0.76A 5lf3Y-3wxrL:
35.1
5lf3Z-3wxrL:
24.1		 5lf3Y-3wxrL:
65.38
5lf3Z-3wxrL:
24.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR L   1
ALA L  20
THR L  21
ALA L  22
LYS L  33
ALA L  49
TYR L 170
 None
 0.50A 5lf3Y-3wxrL:
35.1
5lf3Z-3wxrL:
24.1		 5lf3Y-3wxrL:
65.38
5lf3Z-3wxrL:
24.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
TYR L 170
 None
 0.90A 5lf3Y-3wxrL:
35.1
5lf3Z-3wxrL:
24.1		 5lf3Y-3wxrL:
65.38
5lf3Z-3wxrL:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.78A 5lf7V-3wxrL:
29.8
5lf7b-3wxrL:
28.5		 5lf7V-3wxrL:
28.09
5lf7b-3wxrL:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   2
THR L   1
SER L 174
GLY L 173
ALA L 165
 None
 0.92A 5lf7V-3wxrL:
29.8
5lf7b-3wxrL:
28.5		 5lf7V-3wxrL:
28.09
5lf7b-3wxrL:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  20
ALA L  46
GLY L  47
ALA L  49
 None
 0.61A 5lf7H-3wxrL:
29.9
5lf7I-3wxrL:
25.2		 5lf7H-3wxrL:
28.09
5lf7I-3wxrL:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  20
THR L  21
ALA L  46
ALA L  49
 None
 0.80A 5lf7H-3wxrL:
29.9
5lf7I-3wxrL:
25.2		 5lf7H-3wxrL:
28.09
5lf7I-3wxrL:
23.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 ALA L  20
ALA L  22
VAL L  31
LYS L  33
GLY L  48
 None
 0.85A 5lf7K-3wxrL:
34.9
5lf7L-3wxrL:
24.2		 5lf7K-3wxrL:
65.38
5lf7L-3wxrL:
24.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR L   1
ALA L  20
ALA L  22
VAL L  31
LYS L  33
GLY L  47
 None
 0.51A 5lf7K-3wxrL:
34.9
5lf7L-3wxrL:
24.2		 5lf7K-3wxrL:
65.38
5lf7L-3wxrL:
24.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR L   1
ALA L  20
THR L  21
ALA L  22
VAL L  31
LYS L  33
 None
 0.34A 5lf7K-3wxrL:
34.9
5lf7L-3wxrL:
24.2		 5lf7K-3wxrL:
65.38
5lf7L-3wxrL:
24.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR L   1
ALA L  20
THR L  21
VAL L  31
LYS L  33
GLY L  47
 None
 0.97A 5lf7K-3wxrL:
34.9
5lf7L-3wxrL:
24.2		 5lf7K-3wxrL:
65.38
5lf7L-3wxrL:
24.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR L   1
ALA L  20
VAL L  31
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.62A 5lf7K-3wxrL:
34.9
5lf7L-3wxrL:
24.2		 5lf7K-3wxrL:
65.38
5lf7L-3wxrL:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.78A 5lf7H-3wxrL:
29.9
5lf7N-3wxrL:
28.5		 5lf7H-3wxrL:
28.09
5lf7N-3wxrL:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   2
THR L   1
SER L 174
GLY L 173
ALA L 165
 None
 0.93A 5lf7H-3wxrL:
29.9
5lf7N-3wxrL:
28.5		 5lf7H-3wxrL:
28.09
5lf7N-3wxrL:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  20
ALA L  46
GLY L  47
ALA L  49
 None
 0.58A 5lf7V-3wxrL:
29.8
5lf7W-3wxrL:
25.3		 5lf7V-3wxrL:
28.09
5lf7W-3wxrL:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  20
THR L  21
ALA L  46
ALA L  49
 None
 0.79A 5lf7V-3wxrL:
29.8
5lf7W-3wxrL:
25.3		 5lf7V-3wxrL:
28.09
5lf7W-3wxrL:
23.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 ALA L  20
ALA L  22
VAL L  31
LYS L  33
GLY L  48
 None
 0.84A 5lf7Y-3wxrL:
34.9
5lf7Z-3wxrL:
24.2		 5lf7Y-3wxrL:
65.38
5lf7Z-3wxrL:
24.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR L   1
ALA L  20
ALA L  22
VAL L  31
LYS L  33
GLY L  47
GLY L  48
 None
 0.69A 5lf7Y-3wxrL:
34.9
5lf7Z-3wxrL:
24.2		 5lf7Y-3wxrL:
65.38
5lf7Z-3wxrL:
24.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR L   1
ALA L  20
THR L  21
ALA L  22
VAL L  31
LYS L  33
 None
 0.32A 5lf7Y-3wxrL:
34.9
5lf7Z-3wxrL:
24.2		 5lf7Y-3wxrL:
65.38
5lf7Z-3wxrL:
24.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR L   1
ALA L  20
THR L  21
VAL L  31
LYS L  33
GLY L  47
 None
 0.95A 5lf7Y-3wxrL:
34.9
5lf7Z-3wxrL:
24.2		 5lf7Y-3wxrL:
65.38
5lf7Z-3wxrL:
24.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR L   1
ALA L  20
VAL L  31
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.62A 5lf7Y-3wxrL:
34.9
5lf7Z-3wxrL:
24.2		 5lf7Y-3wxrL:
65.38
5lf7Z-3wxrL:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
(Saccharomyces
cerevisiae) 		5 / 12 ASP K  32
SER K  16
ALA K  46
GLN K  64
LEU K  37
 None
 1.20A 5tudD-3wxrK:
undetectable		 5tudD-3wxrK:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		5 / 12 ALA G 195
GLU G 212
LEU G 235
ILE G 239
PHE G 211
 None
 1.24A 5vlmE-3wxrG:
undetectable		 5vlmE-3wxrG:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 3wxr PROBABLE PROTEASOME
SUBUNIT ALPHA TYPE-7
(Saccharomyces
cerevisiae) 		4 / 7 GLY G 116
SER G 155
GLY G 154
VAL G 119
 None
 0.94A 6ekzA-3wxrG:
undetectable		 6ekzA-3wxrG:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3wxr PROTEASOME SUBUNIT
BETA TYPE-4
PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 8 ASP L 125
ARG L   7
LYS L 123
GLN K  60
 None
 1.29A 6fbvD-3wxrL:
0.5		 6fbvD-3wxrL:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.67A 6hwdV-3wxrL:
28.8
6hwdb-3wxrL:
28.7		 6hwdV-3wxrL:
21.43
6hwdb-3wxrL:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
THR L  21
ALA L  27
LYS L  33
ALA L  49
 None
 0.73A 6hwdV-3wxrL:
28.8
6hwdb-3wxrL:
28.7		 6hwdV-3wxrL:
21.43
6hwdb-3wxrL:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 12 THR L   1
ALA L  27
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.63A 6hwdH-3wxrL:
27.2
6hwdI-3wxrL:
25.4		 6hwdH-3wxrL:
21.43
6hwdI-3wxrL:
16.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 11 THR L   1
ALA L  20
ALA L  22
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.74A 6hwdK-3wxrL:
37.2
6hwdL-3wxrL:
23.4		 6hwdK-3wxrL:
100.00
6hwdL-3wxrL:
15.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR L   1
ALA L  20
THR L  21
ALA L  22
ALA L  27
LYS L  33
ALA L  49
 None
 0.59A 6hwdK-3wxrL:
37.2
6hwdL-3wxrL:
23.4		 6hwdK-3wxrL:
100.00
6hwdL-3wxrL:
15.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.93A 6hwdK-3wxrL:
37.2
6hwdL-3wxrL:
23.4		 6hwdK-3wxrL:
100.00
6hwdL-3wxrL:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
ALA L  27
LYS L  33
GLY L  47
ALA L  49
 None
 0.67A 6hwdH-3wxrL:
27.2
6hwdN-3wxrL:
28.7		 6hwdH-3wxrL:
21.43
6hwdN-3wxrL:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 12 THR L   1
THR L  21
ALA L  27
LYS L  33
ALA L  49
 None
 0.73A 6hwdH-3wxrL:
27.2
6hwdN-3wxrL:
28.7		 6hwdH-3wxrL:
21.43
6hwdN-3wxrL:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		6 / 11 THR L   1
ALA L  27
LYS L  33
ALA L  46
GLY L  47
ALA L  49
 None
 0.63A 6hwdV-3wxrL:
28.8		 6hwdV-3wxrL:
21.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		8 / 11 THR L   1
ALA L  20
ALA L  22
ALA L  27
LYS L  33
GLY L  47
GLY L  48
ALA L  49
 None
 0.74A 6hwdY-3wxrL:
37.2
6hwdZ-3wxrL:
23.1		 6hwdY-3wxrL:
100.00
6hwdZ-3wxrL:
15.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		7 / 11 THR L   1
ALA L  20
THR L  21
ALA L  22
ALA L  27
LYS L  33
ALA L  49
 None
 0.59A 6hwdY-3wxrL:
37.2
6hwdZ-3wxrL:
23.1		 6hwdY-3wxrL:
100.00
6hwdZ-3wxrL:
15.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3wxr PROTEASOME SUBUNIT
BETA TYPE-5
(Saccharomyces
cerevisiae) 		5 / 11 THR L   1
ALA L  20
THR L  21
LYS L  33
GLY L  47
 None
 0.93A 6hwdY-3wxrL:
37.2
6hwdZ-3wxrL:
23.1		 6hwdY-3wxrL:
100.00
6hwdZ-3wxrL:
15.73