SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wxy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 12 LEU A 372
GLY A 154
GLY A 376
ILE A 349
LEU A 222
 None
 0.95A 1p91B-3wxyA:
undetectable		 1p91B-3wxyA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 12 ASN A 343
GLY A 341
ILE A 379
GLY A 156
SER A 346
 None
 1.13A 1q8jB-3wxyA:
undetectable		 1q8jB-3wxyA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		4 / 7 LEU A  96
GLU A  91
LEU A  88
TYR A  64
 None
 1.24A 2w8yA-3wxyA:
undetectable		 2w8yA-3wxyA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 11 ALA A 254
GLY A 154
HIS A 377
GLY A 312
HIS A 310
 None
None
None
COA  A 401 (-3.8A)
None
 1.08A 2x1lA-3wxyA:
undetectable		 2x1lA-3wxyA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 11 ALA A 254
GLY A 154
HIS A 377
GLY A 312
HIS A 310
 None
None
None
COA  A 401 (-3.8A)
None
 1.12A 2x1lC-3wxyA:
undetectable		 2x1lC-3wxyA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 12 GLY A 312
ILE A 345
GLY A 154
HIS A 377
LEU A 212
 COA  A 401 (-3.8A)
None
None
None
None
 1.18A 3eeyE-3wxyA:
undetectable		 3eeyE-3wxyA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 12 GLY A 312
ILE A 345
GLY A 154
HIS A 377
LEU A 212
 COA  A 401 (-3.8A)
None
None
None
None
 1.11A 3eeyF-3wxyA:
undetectable		 3eeyF-3wxyA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 12 GLY A 312
ILE A 345
GLY A 154
HIS A 377
LEU A 212
 COA  A 401 (-3.8A)
None
None
None
None
 1.18A 3eeyJ-3wxyA:
undetectable		 3eeyJ-3wxyA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 10 ALA A  21
ASP A 107
ILE A 105
ILE A 183
ALA A  97
 None
 0.95A 3ekwA-3wxyA:
undetectable		 3ekwA-3wxyA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3T_G_ACTG701_0
(NUCLEOTIDE-BINDING
PROTEIN, UNIVERSAL
STRESS PROTEIN USPA
FAMILY)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		4 / 4 HIS A  75
ILE A  37
ARG A  40
HIS A  41
 None
 1.01A 3s3tG-3wxyA:
0.0
3s3tH-3wxyA:
0.0		 3s3tG-3wxyA:
18.28
3s3tH-3wxyA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 11 LEU A 286
ALA A 373
ILE A 375
GLY A 156
PRO A 244
 None
 1.03A 3spkA-3wxyA:
undetectable		 3spkA-3wxyA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 12 LEU A 317
ILE A  60
ILE A 349
ASP A 340
ALA A 337
 None
 0.96A 3uj7A-3wxyA:
undetectable		 3uj7A-3wxyA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 12 ILE A 183
ALA A 181
LEU A 168
ILE A 159
LEU A 150
 None
 1.32A 3uvvB-3wxyA:
undetectable		 3uvvB-3wxyA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 12 ASP A  86
ASP A 132
ARG A 147
ASN A 125
HIS A 151
 None
 1.25A 4fewC-3wxyA:
0.0
4fewD-3wxyA:
0.0
4fewF-3wxyA:
0.0		 4fewC-3wxyA:
19.47
4fewD-3wxyA:
19.47
4fewF-3wxyA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMU_C_RFPC1401_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 12 ASP A 198
ARG A 194
LEU A  29
ARG A  63
ILE A  37
 None
 1.47A 4kmuC-3wxyA:
undetectable		 4kmuC-3wxyA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 11 GLY A 158
GLY A 157
GLY A 156
ALA A 185
GLU A 187
 None
 1.17A 4l8fB-3wxyA:
undetectable		 4l8fB-3wxyA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 11 ASN A  55
LEU A  52
LEU A  48
ALA A 193
LEU A 197
 None
 1.22A 4wg0H-3wxyA:
undetectable
4wg0I-3wxyA:
undetectable
4wg0J-3wxyA:
undetectable		 4wg0H-3wxyA:
3.08
4wg0I-3wxyA:
3.08
4wg0J-3wxyA:
3.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 11 ALA A 193
LEU A 197
ASN A  55
LEU A  52
LEU A  48
 None
 1.18A 4wg0I-3wxyA:
undetectable
4wg0J-3wxyA:
undetectable
4wg0K-3wxyA:
undetectable		 4wg0I-3wxyA:
3.08
4wg0J-3wxyA:
3.08
4wg0K-3wxyA:
3.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 11 ALA A 373
LEU A 372
LEU A 370
LEU A 356
LEU A 353
 None
 1.06A 4wg0K-3wxyA:
undetectable
4wg0L-3wxyA:
undetectable
4wg0M-3wxyA:
undetectable		 4wg0K-3wxyA:
3.08
4wg0L-3wxyA:
3.08
4wg0M-3wxyA:
3.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 12 LEU A 386
ILE A 352
ILE A 349
VAL A 279
LEU A 324
 None
 0.92A 4y0pA-3wxyA:
undetectable		 4y0pA-3wxyA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		4 / 7 ILE A 153
CYH A 123
GLY A 158
GLY A 157
 None
 0.82A 5a06A-3wxyA:
undetectable		 5a06A-3wxyA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		4 / 7 ILE A 153
CYH A 123
GLY A 158
GLY A 157
 None
 0.81A 5a06B-3wxyA:
undetectable		 5a06B-3wxyA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		4 / 7 ILE A 153
CYH A 123
GLY A 158
GLY A 157
 None
 0.81A 5a06C-3wxyA:
undetectable		 5a06C-3wxyA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_E_SORE1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		4 / 7 ILE A 153
CYH A 123
GLY A 158
GLY A 157
 None
 0.82A 5a06E-3wxyA:
undetectable		 5a06E-3wxyA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G44_A_YTZA1512_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 9 LEU A 220
LEU A 222
ALA A 185
VAL A 121
ALA A 165
 None
 1.47A 5g44A-3wxyA:
undetectable		 5g44A-3wxyA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		3 / 3 HIS A 310
SER A 346
ARG A 351
 None
 0.99A 5u63A-3wxyA:
undetectable		 5u63A-3wxyA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WWS_B_SAMB501_0
(PUTATIVE
METHYLTRANSFERASE
NSUN6)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		5 / 12 CYH A  24
ALA A 217
GLY A  93
ILE A 350
ASP A 215
 None
 1.11A 5wwsB-3wxyA:
undetectable		 5wwsB-3wxyA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 3wxy PUTATIVE
UNCHARACTERIZED
PROTEIN CSYB
(Aspergillus
oryzae) 		4 / 7 ASP A 107
ARG A 103
GLN A 233
LYS A 361
 None
 1.06A 6g31A-3wxyA:
undetectable		 6g31A-3wxyA:
12.23