SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wy8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 3wy8 SERINE PROTEASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 LEU A 141
GLY A 173
PRO A 174
SER A 181
PHE A 176
 None
 1.39A 1fdsA-3wy8A:
undetectable		 1fdsA-3wy8A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 3wy8 SERINE PROTEASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 ALA A  79
PHE A  56
ALA A 216
THR A  37
GLY A  27
 None
 1.14A 2ve3B-3wy8A:
undetectable		 2ve3B-3wy8A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 3wy8 SERINE PROTEASE
(Paenarthrobacter
nicotinovorans) 		4 / 6 ALA A  32
SER A 219
THR A  37
VAL A  30
 None
 1.05A 3d2tB-3wy8A:
undetectable		 3d2tB-3wy8A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 3wy8 SERINE PROTEASE
(Paenarthrobacter
nicotinovorans) 		5 / 12 SER A 170
GLY A 172
GLY A 173
TRP A 175
ASP A  92
 None
 1.05A 4b17A-3wy8A:
undetectable		 4b17A-3wy8A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 3wy8 SERINE PROTEASE
(Paenarthrobacter
nicotinovorans) 		4 / 6 GLY A  12
SER A  26
TYR A 130
GLY A 173
 None
 0.74A 5k4pA-3wy8A:
undetectable		 5k4pA-3wy8A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 3wy8 SERINE PROTEASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 TRP A  72
MET A  98
ASN A  99
 None
 1.10A 5uc1B-3wy8A:
undetectable		 5uc1B-3wy8A:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 3wy8 SERINE PROTEASE
(Paenarthrobacter
nicotinovorans) 		3 / 3 TRP A  72
MET A  98
ASN A  99
 None
 1.09A 5uc1A-3wy8A:
undetectable		 5uc1A-3wy8A:
18.27