SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wyr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R94_A_FLRA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3wyr KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DL4
(Homo
sapiens) 		5 / 12 HIS A  80
SER A  81
PHE A  34
PHE A  77
TYR A  30
 None
 1.40A 3r94A-3wyrA:
undetectable		 3r94A-3wyrA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3wyr KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DL4
(Homo
sapiens) 		5 / 12 ASP A  43
ILE A  94
LEU A  26
GLY A  44
LEU A  39
 None
 1.00A 3vasB-3wyrA:
undetectable		 3vasB-3wyrA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 3wyr KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DL4
(Homo
sapiens) 		4 / 7 TYR A  72
LEU A  50
VAL A  18
VAL A  96
 None
 1.01A 4cp4A-3wyrA:
undetectable		 4cp4A-3wyrA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3wyr KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DL4
(Homo
sapiens) 		4 / 8 TYR A  72
LEU A  50
VAL A  18
VAL A  96
 None
 0.96A 4l4bA-3wyrA:
undetectable		 4l4bA-3wyrA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 3wyr KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DL4
(Homo
sapiens) 		5 / 12 PRO A 180
MET A  95
ILE A  94
LEU A  26
LEU A  50
 None
 1.16A 6b52A-3wyrA:
undetectable		 6b52A-3wyrA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3wyr KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DL4
(Homo
sapiens) 		4 / 8 TYR A  72
LEU A  50
VAL A  18
VAL A  96
 None
 0.96A 6cp4A-3wyrA:
undetectable		 6cp4A-3wyrA:
21.15