SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 3wz1 AGARASE
(Microbulbifer
thermotolerans) 		4 / 7 TRP A 138
GLU A 257
SER A 109
THR A 111
 None
 1.22A 3dzgB-3wz1A:
undetectable		 3dzgB-3wz1A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROP_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 3wz1 AGARASE
(Microbulbifer
thermotolerans) 		4 / 6 TRP A 138
GLU A 257
SER A 109
THR A 111
 None
 1.28A 3ropA-3wz1A:
undetectable		 3ropA-3wz1A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 3wz1 AGARASE
(Microbulbifer
thermotolerans) 		3 / 3 TRP A  72
TRP A  80
THR A  78
 None
 1.26A 4bboB-3wz1A:
undetectable		 4bboB-3wz1A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3wz1 AGARASE
(Microbulbifer
thermotolerans) 		4 / 8 SER A 144
ASN A  70
ILE A  69
TRP A 138
 None
 1.03A 4d39A-3wz1A:
undetectable		 4d39A-3wz1A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 3wz1 AGARASE
(Microbulbifer
thermotolerans) 		3 / 3 ARG A  63
ASP A  45
TRP A  64
 None
 1.09A 4xdqA-3wz1A:
19.1		 4xdqA-3wz1A:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 3wz1 AGARASE
(Microbulbifer
thermotolerans) 		3 / 3 THR A 270
ASP A 271
ALA A 272
 None
 0.08A 5g5gB-3wz1A:
undetectable		 5g5gB-3wz1A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 3wz1 AGARASE
(Microbulbifer
thermotolerans) 		5 / 11 HIS A 169
HIS A 173
VAL A 174
ASP A 236
PRO A 237
 GOL  A 404 (-4.1A)
GOL  A 404 (-4.7A)
None
None
None
 0.85A 5z0fA-3wz1A:
undetectable
5z0fB-3wz1A:
undetectable		 5z0fA-3wz1A:
13.12
5z0fB-3wz1A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 3wz1 AGARASE
(Microbulbifer
thermotolerans) 		5 / 11 HIS A 169
HIS A 173
VAL A 174
SER A 171
ASP A 236
 GOL  A 404 (-4.1A)
GOL  A 404 (-4.7A)
None
None
None
 1.32A 5z0fA-3wz1A:
undetectable
5z0fB-3wz1A:
undetectable		 5z0fA-3wz1A:
13.12
5z0fB-3wz1A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 3wz1 AGARASE
(Microbulbifer
thermotolerans) 		5 / 11 HIS A 169
HIS A 173
VAL A 174
ASP A 236
PRO A 237
 GOL  A 404 (-4.1A)
GOL  A 404 (-4.7A)
None
None
None
 0.95A 5z0gA-3wz1A:
undetectable
5z0gB-3wz1A:
undetectable		 5z0gA-3wz1A:
13.12
5z0gB-3wz1A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 3wz1 AGARASE
(Microbulbifer
thermotolerans) 		5 / 11 HIS A 169
HIS A 173
VAL A 174
SER A 171
ASP A 236
 GOL  A 404 (-4.1A)
GOL  A 404 (-4.7A)
None
None
None
 1.34A 5z0gA-3wz1A:
undetectable
5z0gB-3wz1A:
undetectable		 5z0gA-3wz1A:
13.12
5z0gB-3wz1A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3wz1 AGARASE
(Microbulbifer
thermotolerans) 		3 / 3 TYR A 183
ASP A 182
GLN A 184
 None
None
GOL  A 404 (-2.6A)
 0.94A 6g1pA-3wz1A:
undetectable		 6g1pA-3wz1A:
22.89