SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wz3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_B_SALB503_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 3wz3 TRAM PROTEIN
(Plasmid
R64) 		5 / 10 ALA A 103
LEU A 104
PHE A 108
PHE A 126
PHE A 131
 None
 1.37A 1y7iB-3wz3A:
undetectable		 1y7iB-3wz3A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3wz3 TRAM PROTEIN
(Plasmid
R64) 		4 / 8 LEU A 122
LEU A 138
ALA A 137
PHE A 108
 None
 0.85A 2vcvP-3wz3A:
undetectable		 2vcvP-3wz3A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 3wz3 TRAM PROTEIN
(Plasmid
R64) 		5 / 6 ALA A 137
LEU A 138
ALA A 107
THR A 106
ASN A 109
 None
 1.29A 3b6hA-3wz3A:
undetectable		 3b6hA-3wz3A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 3wz3 TRAM PROTEIN
(Plasmid
R64) 		5 / 6 ALA A 137
LEU A 138
ALA A 107
THR A 106
ASN A 109
 None
 1.31A 3b6hB-3wz3A:
undetectable		 3b6hB-3wz3A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 3wz3 TRAM PROTEIN
(Plasmid
R64) 		4 / 5 VAL A 182
ARG A 183
MET A 184
GLU A 195
 None
 1.39A 4hojA-3wz3A:
undetectable		 4hojA-3wz3A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 3wz3 TRAM PROTEIN
(Plasmid
R64) 		3 / 3 LYS A 212
PRO A 213
SER A 214
 SO4  A 301 ( 4.5A)
None
None
 0.40A 4k50I-3wz3A:
1.6		 4k50I-3wz3A:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 3wz3 TRAM PROTEIN
(Plasmid
R64) 		3 / 3 TRP A 176
MET A  97
ASN A  94
 None
 1.37A 5uc1B-3wz3A:
undetectable		 5uc1B-3wz3A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 3wz3 TRAM PROTEIN
(Plasmid
R64) 		3 / 3 TRP A 176
MET A  97
ASN A  94
 None
 1.31A 5uc1A-3wz3A:
undetectable		 5uc1A-3wz3A:
17.97