SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wzi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 3wzi UNCHARACTERIZED
PROTEIN AF_1864
(Archaeoglobus
fulgidus) 		4 / 8 ILE A  30
LEU A  55
PHE A  16
GLY A  47
 None
None
None
U  C   2 ( 3.6A)
 0.90A 1os6A-3wziA:
undetectable		 1os6A-3wziA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3wzi UNCHARACTERIZED
PROTEIN AF_1864
(Archaeoglobus
fulgidus) 		4 / 8 SER A  44
ARG A  46
VAL A  93
LEU A  97
 A  C   3 ( 4.4A)
A  C   3 ( 4.5A)
None
None
 1.01A 3ax7A-3wziA:
undetectable		 3ax7A-3wziA:
5.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 3wzi UNCHARACTERIZED
PROTEIN AF_1864
(Archaeoglobus
fulgidus) 		5 / 12 GLN A  78
HIS A  61
VAL A  65
ILE A  43
VAL A  41
 None
 0.89A 3fw3A-3wziA:
undetectable		 3fw3A-3wziA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 3wzi UNCHARACTERIZED
PROTEIN AF_1864
(Archaeoglobus
fulgidus) 		5 / 12 GLN A  78
HIS A  61
VAL A  65
ILE A  43
VAL A  41
 None
 1.00A 3fw3B-3wziA:
undetectable		 3fw3B-3wziA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 3wzi UNCHARACTERIZED
PROTEIN AF_1864
(Archaeoglobus
fulgidus) 		4 / 8 ILE A  30
LEU A  55
PHE A  16
GLY A  47
 None
None
None
U  C   2 ( 3.6A)
 0.92A 3selX-3wziA:
undetectable		 3selX-3wziA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 3wzi UNCHARACTERIZED
PROTEIN AF_1864
(Archaeoglobus
fulgidus) 		4 / 6 ILE A  30
LEU A  55
PHE A  16
GLY A  47
 None
None
None
U  C   2 ( 3.6A)
 0.84A 3sj1X-3wziA:
undetectable		 3sj1X-3wziA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 3wzi UNCHARACTERIZED
PROTEIN AF_1864
(Archaeoglobus
fulgidus) 		4 / 7 ILE A  30
LEU A  55
PHE A  16
GLY A  47
 None
None
None
U  C   2 ( 3.6A)
 0.94A 4hc3A-3wziA:
undetectable		 4hc3A-3wziA:
20.72