SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3x0t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 3x0t UNCHARACTERIZED
PROTEIN
(Vibrio
parahaemolyticus) 		5 / 10 VAL A  17
GLY A 104
VAL A  95
GLN A  56
GLY A  22
 None
 1.22A 3km6A-3x0tA:
undetectable		 3km6A-3x0tA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 3x0t UNCHARACTERIZED
PROTEIN
(Vibrio
parahaemolyticus) 		3 / 3 ARG A  39
LEU A 112
GLU A 113
 None
 0.69A 4l3gF-3x0tA:
undetectable		 4l3gF-3x0tA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3x0t UNCHARACTERIZED
PROTEIN
(Vibrio
parahaemolyticus) 		4 / 4 ASN A  99
VAL A  17
THR A  52
ILE A  53
 None
 1.47A 4retA-3x0tA:
undetectable		 4retA-3x0tA:
7.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3x0t UNCHARACTERIZED
PROTEIN
(Vibrio
parahaemolyticus) 		4 / 4 ASN A  99
VAL A  17
THR A  52
ILE A  53
 None
 1.47A 4retC-3x0tA:
undetectable		 4retC-3x0tA:
7.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3x0t UNCHARACTERIZED
PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 THR A  24
ARG A  39
HIS A 111
ASP A  27
 None
 1.31A 6mn4E-3x0tA:
undetectable		 6mn4E-3x0tA:
16.54