SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3x0v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 LEU A 406
LEU A 403
ASN A 402
LEU A 400
THR A 343
 None
 1.18A 1a28B-3x0vA:
undetectable		 1a28B-3x0vA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 LEU A 403
ALA A 367
PHE A  54
LEU A 398
PHE A 324
 None
 1.42A 1brpA-3x0vA:
undetectable		 1brpA-3x0vA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 LEU A 291
LEU A 296
VAL A 282
ALA A 458
ALA A 459
 None
 1.15A 1n5xA-3x0vA:
undetectable		 1n5xA-3x0vA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 LEU A 291
LEU A 296
VAL A 282
ALA A 458
ALA A 459
 None
 1.15A 1n5xB-3x0vA:
undetectable		 1n5xB-3x0vA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 7 ALA A 438
GLY A  65
ILE A  64
THR A 370
 FAD  A 601 (-3.7A)
FAD  A 601 (-4.1A)
None
None
 0.69A 1t7iB-3x0vA:
undetectable		 1t7iB-3x0vA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 7 ARG A  68
PHE A 216
TYR A 369
TRP A 476
 EPE  A 602 ( 3.1A)
EPE  A 602 (-3.5A)
EPE  A 602 (-4.9A)
None
 0.66A 1tdnA-3x0vA:
37.8		 1tdnA-3x0vA:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 LEU A 406
LEU A 403
ASN A 402
LEU A 400
THR A 343
 None
 1.12A 1zucB-3x0vA:
undetectable		 1zucB-3x0vA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 6 THR A 349
THR A 370
ASN A 200
ASP A 203
 EPE  A 602 ( 4.0A)
None
None
None
 1.17A 2okcA-3x0vA:
undetectable		 2okcA-3x0vA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 6 THR A 376
ASP A 374
THR A 199
ASP A 344
 None
 1.22A 2okcB-3x0vA:
undetectable		 2okcB-3x0vA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 6 THR A  45
GLU A  40
PHE A  39
ILE A  12
 None
FAD  A 601 (-2.7A)
None
None
 1.28A 2w98B-3x0vA:
3.2		 2w98B-3x0vA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 8 GLY A 467
ILE A 309
MET A 455
HIS A 474
 FAD  A 601 (-3.4A)
None
None
None
 0.89A 2x0pA-3x0vA:
undetectable		 2x0pA-3x0vA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 GLY A 437
ALA A 438
GLY A  65
ILE A  64
THR A 370
 None
FAD  A 601 (-3.7A)
FAD  A 601 (-4.1A)
None
None
 0.90A 3el5B-3x0vA:
undetectable		 3el5B-3x0vA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 9 GLY A 437
ALA A 438
GLY A  65
ILE A  64
THR A 370
 None
FAD  A 601 (-3.7A)
FAD  A 601 (-4.1A)
None
None
 0.96A 3gguB-3x0vA:
undetectable		 3gguB-3x0vA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_A_SAMA6734_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 VAL A  17
GLY A  47
TYR A  50
LEU A  81
TYR A  69
 FAD  A 601 (-4.4A)
FAD  A 601 (-3.4A)
None
None
FAD  A 601 (-4.3A)
 1.09A 3qxyA-3x0vA:
undetectable		 3qxyA-3x0vA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 11 VAL A  17
GLY A  47
TYR A  50
LEU A  81
TYR A  69
 FAD  A 601 (-4.4A)
FAD  A 601 (-3.4A)
None
None
FAD  A 601 (-4.3A)
 1.12A 3rc0A-3x0vA:
undetectable		 3rc0A-3x0vA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_B_SAMB480_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 VAL A  17
GLY A  47
TYR A  50
LEU A  81
TYR A  69
 FAD  A 601 (-4.4A)
FAD  A 601 (-3.4A)
None
None
FAD  A 601 (-4.3A)
 1.07A 3rc0B-3x0vA:
undetectable		 3rc0B-3x0vA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 11 PHE A 202
GLU A 193
THR A 194
VAL A 126
PRO A 127
 None
 1.11A 3tmzA-3x0vA:
undetectable		 3tmzA-3x0vA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		3 / 3 ARG A 251
MET A 294
ARG A 293
 None
FAD  A 601 (-4.9A)
None
 1.23A 3uvvA-3x0vA:
undetectable		 3uvvA-3x0vA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 LEU A 296
MET A 294
LEU A 288
ILE A 309
ALA A 308
 None
FAD  A 601 (-4.9A)
None
None
None
 1.00A 3vrmA-3x0vA:
undetectable		 3vrmA-3x0vA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 8 VAL A 282
VAL A  13
ILE A 271
PHE A  39
 None
FAD  A 601 (-4.7A)
None
None
 0.62A 3warA-3x0vA:
undetectable		 3warA-3x0vA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 LEU A 406
LEU A 403
ASN A 402
LEU A 400
THR A 343
 None
 1.10A 4fn9B-3x0vA:
undetectable		 4fn9B-3x0vA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		3 / 3 ASP A 292
ARG A 310
ASP A 295
 None
 0.76A 4fp9C-3x0vA:
2.5		 4fp9C-3x0vA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		3 / 3 ASP A 292
ARG A 310
ASP A 295
 None
 0.77A 4fp9F-3x0vA:
2.4		 4fp9F-3x0vA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 LEU A 441
ALA A 308
MET A 161
LEU A 149
PHE A 157
 None
 1.32A 4iaqA-3x0vA:
undetectable		 4iaqA-3x0vA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 LEU A 441
ALA A 308
MET A 161
LEU A 149
PHE A 157
 None
 1.24A 4iarA-3x0vA:
undetectable		 4iarA-3x0vA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 7 ALA A  23
GLY A  14
ALA A  15
THR A  45
 None
FAD  A 601 (-3.2A)
None
None
 0.89A 4r1zB-3x0vA:
undetectable		 4r1zB-3x0vA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 7 LEU A 296
LEU A 301
ALA A 458
LEU A 291
 None
 0.67A 4z90F-3x0vA:
undetectable
4z90G-3x0vA:
undetectable
4z90H-3x0vA:
undetectable
4z90J-3x0vA:
undetectable		 4z90F-3x0vA:
21.60
4z90G-3x0vA:
21.60
4z90H-3x0vA:
21.60
4z90J-3x0vA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 7 TYR A  92
ILE A  90
GLY A 230
THR A  51
 None
 0.87A 4ze3A-3x0vA:
undetectable		 4ze3A-3x0vA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 GLY A  14
LEU A 291
LEU A  20
GLY A  47
GLY A 289
 FAD  A 601 (-3.2A)
None
None
FAD  A 601 (-3.4A)
None
 1.12A 5d4uB-3x0vA:
2.7		 5d4uB-3x0vA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 8 TYR A  92
ILE A  90
GLY A 230
THR A  51
 None
 0.73A 5esfA-3x0vA:
undetectable		 5esfA-3x0vA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 8 TYR A  92
ILE A  90
GLY A 230
THR A  51
 None
 0.81A 5esjA-3x0vA:
undetectable		 5esjA-3x0vA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 7 TYR A  92
ILE A  90
GLY A 230
THR A  51
 None
 0.75A 5esmA-3x0vA:
undetectable		 5esmA-3x0vA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 8 TYR A  92
ILE A  90
GLY A 230
THR A  51
 None
 0.81A 5hs1A-3x0vA:
undetectable		 5hs1A-3x0vA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 GLY A  47
TYR A  50
PHE A  82
LEU A  81
MET A  87
 FAD  A 601 (-3.4A)
None
None
None
None
 1.49A 5kklB-3x0vA:
undetectable		 5kklB-3x0vA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 8 TYR A  21
TRP A 508
TYR A 485
LEU A  29
 None
 1.22A 5kxiA-3x0vA:
undetectable
5kxiB-3x0vA:
undetectable		 5kxiA-3x0vA:
22.20
5kxiB-3x0vA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		4 / 8 TYR A  21
TRP A 508
TYR A 485
LEU A  29
 None
 1.21A 5kxiD-3x0vA:
undetectable
5kxiE-3x0vA:
undetectable		 5kxiD-3x0vA:
22.20
5kxiE-3x0vA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 LEU A 259
GLY A 265
PRO A 262
ALA A 261
PHE A 491
 None
 1.28A 5x6yA-3x0vA:
undetectable		 5x6yA-3x0vA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 3x0v L-LYSINE OXIDASE
(Trichoderma
viride) 		5 / 12 VAL A 364
GLY A  65
MET A  67
ARG A  68
THR A 370
 None
FAD  A 601 (-4.1A)
None
EPE  A 602 ( 3.1A)
None
 1.16A 6brdC-3x0vA:
2.2		 6brdC-3x0vA:
9.28