SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3x17'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 6 PHE B 314
VAL B 244
ALA B 209
LEU B 213
 None
 0.78A 1e7bB-3x17B:
1.6		 1e7bB-3x17B:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 10 VAL B 498
VAL B 137
TYR B 134
VAL B 133
ILE B 130
 None
 1.09A 1fe2A-3x17B:
undetectable		 1fe2A-3x17B:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_B_T44B328_1
(TRANSTHYRETIN)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 8 ALA B 331
LEU B 329
ALA B 260
THR B 293
 None
 0.83A 1ie4B-3x17B:
4.1
1ie4D-3x17B:
4.3		 1ie4B-3x17B:
14.93
1ie4D-3x17B:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA154_1
(CALMODULIN)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 7 GLU B 217
LEU B 218
LEU B 400
GLU B 364
 None
 1.07A 1linA-3x17B:
undetectable		 1linA-3x17B:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 12 PHE B 328
LEU B 329
ASP B 258
ALA B 318
VAL B 261
 None
 1.12A 2g70A-3x17B:
undetectable		 2g70A-3x17B:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 12 PHE B 328
LEU B 329
ASP B 258
ALA B 318
VAL B 261
 None
 1.11A 2g70B-3x17B:
undetectable		 2g70B-3x17B:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 12 VAL B  96
VAL B 526
ASN B 504
ASN B 491
TYR B 486
 None
 1.33A 2y00A-3x17B:
undetectable		 2y00A-3x17B:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 12 PRO B 397
PHE B 403
GLY B 401
LEU B 408
VAL B 367
 None
 1.24A 2zifA-3x17B:
undetectable		 2zifA-3x17B:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 8 LEU B 147
ILE B 154
HIS B 163
GLY B 151
 None
 0.78A 3b9lA-3x17B:
undetectable		 3b9lA-3x17B:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWQ_C_VIAC901_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
CATALYTIC DOMAIN,
CONE CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE
SUBUNIT ALPHA
CHIMERA)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 7 TYR B 219
MET B 302
LEU B 408
VAL B 392
 None
 1.11A 3jwqC-3x17B:
undetectable		 3jwqC-3x17B:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 8 PHE B 223
ALA B 222
ALA B 575
LEU B 484
 None
 1.06A 3l4dD-3x17B:
undetectable		 3l4dD-3x17B:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 7 PRO B 387
LEU B 463
GLY B 401
ALA B 398
PHE B 359
 None
 1.28A 3tehB-3x17B:
undetectable		 3tehB-3x17B:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 5 ASP B 404
THR B 407
LEU B 408
GLU B 217
 None
 1.27A 4a3pA-3x17B:
undetectable		 4a3pA-3x17B:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 7 ALA B 215
PHE B 223
ALA B 222
ALA B 571
 None
 0.87A 4du2A-3x17B:
undetectable		 4du2A-3x17B:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 7 ALA B 215
PHE B 223
ALA B 222
ALA B 571
 None
 0.82A 4du2B-3x17B:
undetectable		 4du2B-3x17B:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 12 LEU B  31
ALA B  51
MET B  87
GLY B  85
LEU B  71
 None
 1.25A 4j7xB-3x17B:
undetectable		 4j7xB-3x17B:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 8 VAL B 521
HIS B 511
VAL B 161
ILE B 154
 None
 0.93A 4jq1B-3x17B:
undetectable		 4jq1B-3x17B:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		3 / 3 ARG B 478
GLU B 477
PHE B 574
 None
 1.00A 4kszA-3x17B:
undetectable		 4kszA-3x17B:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 8 GLY B 409
GLY B 370
GLU B 323
LEU B 365
 None
 0.83A 4mwzB-3x17B:
undetectable		 4mwzB-3x17B:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 4 ALA B 318
ALA B 321
ALA B 322
ALA B 325
 None
 0.12A 4oadA-3x17B:
undetectable		 4oadA-3x17B:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 5 ILE B 444
VAL B 442
PHE B 574
HIS B 450
 None
 1.32A 4rzvA-3x17B:
undetectable		 4rzvA-3x17B:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 12 LEU B 567
LEU B 484
HIS B 468
LEU B 465
PRO B 566
 None
 1.29A 4xi3D-3x17B:
undetectable		 4xi3D-3x17B:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 7 SER B 125
ASP B  77
ARG B  75
GLY B 113
 None
 1.03A 5btfA-3x17B:
undetectable
5btfC-3x17B:
undetectable
5btfD-3x17B:
undetectable		 5btfA-3x17B:
22.22
5btfC-3x17B:
22.22
5btfD-3x17B:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 6 SER B 125
ASP B  77
ARG B  75
GLY B 113
 None
 0.99A 5cdqA-3x17B:
undetectable
5cdqC-3x17B:
undetectable
5cdqD-3x17B:
undetectable		 5cdqA-3x17B:
21.76
5cdqC-3x17B:
21.76
5cdqD-3x17B:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DGR_A_GCSA602_1
(PUTATIVE
ENDOGLUCANASE-RELATE
D PROTEIN)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 12 ASP B 194
ALA B 195
ASP B 197
TYR B 201
GLU B 558
 None
 0.68A 5dgrA-3x17B:
30.3		 5dgrA-3x17B:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 7 HIS B 263
ILE B 288
VAL B 261
GLN B 291
 None
 1.10A 5kkzC-3x17B:
undetectable
5kkzE-3x17B:
undetectable		 5kkzC-3x17B:
15.45
5kkzE-3x17B:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 7 HIS B 263
ILE B 288
VAL B 261
GLN B 291
 None
 1.09A 5kkzK-3x17B:
undetectable
5kkzQ-3x17B:
undetectable		 5kkzK-3x17B:
21.15
5kkzQ-3x17B:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 7 HIS B 263
ILE B 288
VAL B 261
GLN B 291
 None
 1.14A 5kkzM-3x17B:
undetectable
5kkzO-3x17B:
undetectable		 5kkzM-3x17B:
15.45
5kkzO-3x17B:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 12 ASN B 530
GLY B 528
GLY B 527
VAL B 526
LEU B 493
 None
 1.10A 5uc1B-3x17B:
undetectable		 5uc1B-3x17B:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 5 VAL B 487
PRO B 529
GLY B 527
TYR B 547
 None
 1.30A 5x80A-3x17B:
undetectable
5x80B-3x17B:
undetectable		 5x80A-3x17B:
16.25
5x80B-3x17B:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		4 / 5 PRO B 529
GLY B 527
TYR B 547
VAL B 487
 None
 1.29A 5x80C-3x17B:
undetectable
5x80D-3x17B:
undetectable		 5x80C-3x17B:
16.25
5x80D-3x17B:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		3 / 3 SER B 162
ALA B 153
VAL B 152
 None
 0.47A 5xiwC-3x17B:
undetectable		 5xiwC-3x17B:
9.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 12 LEU B 525
VAL B 498
GLY B 523
PHE B 223
VAL B 570
 None
 1.44A 6a94A-3x17B:
undetectable		 6a94A-3x17B:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 12 ASP B 136
LEU B 465
ALA B 141
LEU B 458
LEU B 488
 None
 1.12A 6ew0B-3x17B:
undetectable		 6ew0B-3x17B:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 12 ASP B 136
LEU B 465
ALA B 141
LEU B 458
LEU B 488
 None
 1.12A 6ew0D-3x17B:
undetectable		 6ew0D-3x17B:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 12 ASP B 136
LEU B 465
ALA B 141
LEU B 458
LEU B 488
 None
 1.12A 6ew0H-3x17B:
undetectable		 6ew0H-3x17B:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 12 ASP B 136
LEU B 465
ALA B 141
LEU B 458
LEU B 488
 None
 1.12A 6ew0I-3x17B:
undetectable		 6ew0I-3x17B:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 3x17 ENDOGLUCANASE
(uncultured
bacterium) 		5 / 11 ASP B  93
SER B 438
GLY B 528
ALA B 560
VAL B 487
 None
 1.18A 6hu9A-3x17B:
0.9
6hu9E-3x17B:
0.6
6hu9I-3x17B:
undetectable		 6hu9A-3x17B:
21.62
6hu9E-3x17B:
16.91
6hu9I-3x17B:
7.26