SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3x1j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 8 THR A  14
GLY A  18
ASP A  19
TYR A 123
 ACO  A 201 ( 4.6A)
DMS  A 208 (-3.5A)
None
DMS  A 208 (-4.1A)
 1.01A 1bu5B-3x1jA:
2.8		 1bu5B-3x1jA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 6 LEU A  86
ILE A  21
VAL A  31
ALA A  24
 None
 0.87A 2j5mA-3x1jA:
undetectable		 2j5mA-3x1jA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A   5
ILE A  13
GLY A  18
HIS A  17
LEU A  20
 None
None
DMS  A 208 (-3.5A)
ACO  A 201 (-4.1A)
None
 1.18A 2j7xA-3x1jA:
undetectable		 2j7xA-3x1jA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A  85
ILE A  32
LEU A  73
PHE A  69
 None
None
ACO  A 201 (-3.9A)
DMS  A 207 (-4.2A)
 1.05A 3rqwI-3x1jA:
undetectable
3rqwJ-3x1jA:
undetectable		 3rqwI-3x1jA:
21.38
3rqwJ-3x1jA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A   5
ILE A  13
GLY A  18
HIS A  17
LEU A  20
 None
None
DMS  A 208 (-3.5A)
ACO  A 201 (-4.1A)
None
 1.29A 4j26A-3x1jA:
undetectable		 4j26A-3x1jA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 7 PRO A  12
VAL A 131
ALA A 135
PHE A 157
 None
 0.71A 4lb2A-3x1jA:
undetectable		 4lb2A-3x1jA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A   5
ILE A  13
GLY A  18
HIS A  17
LEU A  20
 None
None
DMS  A 208 (-3.5A)
ACO  A 201 (-4.1A)
None
 1.10A 4pxmB-3x1jA:
undetectable		 4pxmB-3x1jA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A  76
PRO A   7
ALA A  36
PHE A  10
 PO4  A 202 (-4.3A)
ACO  A 201 (-4.5A)
ACO  A 201 (-3.6A)
ACO  A 201 ( 4.5A)
 1.33A 4w5oA-3x1jA:
2.6		 4w5oA-3x1jA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A  76
PRO A   7
ALA A  36
PHE A  10
 PO4  A 202 (-4.3A)
ACO  A 201 (-4.5A)
ACO  A 201 (-3.6A)
ACO  A 201 ( 4.5A)
 1.30A 4z4dA-3x1jA:
3.0		 4z4dA-3x1jA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 5 PHE A  76
PRO A   7
ALA A  36
PHE A  10
 PO4  A 202 (-4.3A)
ACO  A 201 (-4.5A)
ACO  A 201 (-3.6A)
ACO  A 201 ( 4.5A)
 1.30A 4z4eA-3x1jA:
2.9		 4z4eA-3x1jA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		4 / 4 LEU A 153
ASP A  11
PRO A  12
ARG A 132
 None
None
None
ACO  A 201 ( 4.1A)
 1.24A 6fgdA-3x1jA:
2.8		 6fgdA-3x1jA:
16.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 5 GLY A   8
THR A   9
HIS A  17
SER A 127
SER A 128
 ACO  A 201 (-3.2A)
ACO  A 201 (-3.9A)
ACO  A 201 (-4.1A)
ACO  A 201 (-3.0A)
ACO  A 201 (-3.1A)
 0.79A 6jmjA-3x1jA:
26.1		 6jmjA-3x1jA:
67.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		7 / 7 GLY A   8
THR A   9
PHE A  10
HIS A  17
ARG A  90
SER A 127
SER A 128
 ACO  A 201 (-3.2A)
ACO  A 201 (-3.9A)
ACO  A 201 ( 4.5A)
ACO  A 201 (-4.1A)
ACO  A 201 (-4.4A)
ACO  A 201 (-3.0A)
ACO  A 201 (-3.1A)
 0.93A 6jnhA-3x1jA:
26.2		 6jnhA-3x1jA:
67.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 6 GLY A   8
THR A   9
HIS A  17
ARG A  90
SER A 127
 ACO  A 201 (-3.2A)
ACO  A 201 (-3.9A)
ACO  A 201 (-4.1A)
ACO  A 201 (-4.4A)
ACO  A 201 (-3.0A)
 0.86A 6jogA-3x1jA:
26.1		 6jogA-3x1jA:
67.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3x1j PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE
(Pseudomonas
aeruginosa) 		5 / 6 GLY A   8
THR A   9
HIS A  17
SER A 127
SER A 128
 ACO  A 201 (-3.2A)
ACO  A 201 (-3.9A)
ACO  A 201 (-4.1A)
ACO  A 201 (-3.0A)
ACO  A 201 (-3.1A)
 0.82A 6jogA-3x1jA:
26.1		 6jogA-3x1jA:
67.70