SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3x29'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 3x29 CLAUDIN-19
(Mus
musculus) 		5 / 8 GLY A 178
GLY A 179
GLY A 123
ILE A 120
THR A 185
 None
 1.08A 3d41A-3x29A:
undetectable		 3d41A-3x29A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 3x29 CLAUDIN-19
(Mus
musculus) 		5 / 9 LEU A  50
ALA A 164
VAL A 137
GLY A  20
ILE A  22
 None
 1.22A 3spkA-3x29A:
undetectable		 3spkA-3x29A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 3x29 CLAUDIN-19
(Mus
musculus) 		5 / 11 LEU A  50
ALA A 164
VAL A 137
GLY A  20
ILE A  22
 None
 0.98A 4dqhA-3x29A:
undetectable		 4dqhA-3x29A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3x29 CLAUDIN-19
(Mus
musculus) 		5 / 11 GLY A 123
GLY A 179
GLY A 178
ALA A 183
LEU A 182
 None
 1.00A 4l8fB-3x29A:
undetectable		 4l8fB-3x29A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_B_MTXB301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3x29 CLAUDIN-19
(Mus
musculus) 		5 / 11 GLY A 179
GLY A 178
GLY A  10
ALA A 183
LEU A 182
 None
 1.01A 4l8fB-3x29A:
undetectable		 4l8fB-3x29A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3x29 CLAUDIN-19
(Mus
musculus) 		5 / 11 GLY A 123
GLY A 179
GLY A 178
ALA A 183
LEU A 182
 None
 0.97A 4l8fD-3x29A:
undetectable		 4l8fD-3x29A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 3x29 CLAUDIN-19
(Mus
musculus) 		5 / 11 GLY A 179
GLY A 178
GLY A  10
ALA A 183
LEU A 182
 None
 1.02A 4l8fD-3x29A:
undetectable		 4l8fD-3x29A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 3x29 CLAUDIN-19
(Mus
musculus) 		5 / 12 LEU A  50
ALA A 164
VAL A 137
GLY A  20
ILE A  22
 None
 1.04A 4njuA-3x29A:
undetectable		 4njuA-3x29A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 3x29 CLAUDIN-19
(Mus
musculus) 		5 / 12 LEU A  50
ALA A 164
VAL A 137
GLY A  20
ILE A  22
 None
 1.03A 4njuC-3x29A:
undetectable		 4njuC-3x29A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 3x29 CLAUDIN-19
(Mus
musculus) 		4 / 5 ILE A  21
LEU A 182
GLY A 179
PHE A 126
 None
 0.96A 5kmdC-3x29A:
undetectable
5kmdD-3x29A:
2.5		 5kmdC-3x29A:
20.91
5kmdD-3x29A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3x29 CLAUDIN-19
HEAT-LABILE
ENTEROTOXIN B CHAIN
(Mus
musculus;
Clostridium
perfringens) 		4 / 5 LEU B 223
TYR B 224
LEU A  46
GLU A  48
 None
 1.20A 5weaA-3x29B:
undetectable		 5weaA-3x29B:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 3x29 CLAUDIN-19
(Mus
musculus) 		5 / 9 ALA A  87
GLY A  91
ALA A 172
GLY A 130
SER A 171
 None
 1.16A 6bklE-3x29A:
undetectable
6bklF-3x29A:
undetectable
6bklG-3x29A:
undetectable
6bklH-3x29A:
undetectable		 6bklE-3x29A:
10.29
6bklF-3x29A:
10.29
6bklG-3x29A:
10.29
6bklH-3x29A:
10.29