SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3x37'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 3x37 MITOCHONDRIAL
MORPHOGENESIS
PROTEIN SLD7
(Zygosaccharomyce
s
rouxii) 		4 / 8 PHE B  77
TYR B  76
LEU B 105
VAL B  24
 None
 0.72A 1fslB-3x37B:
undetectable		 1fslB-3x37B:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4J_A_NCAA1002_0
(NAD-DEPENDENT
DEACETYLASE)		 3x37 ZYRO0C14696P
(Zygosaccharomyce
s
rouxii) 		4 / 5 ALA A  95
ILE A  97
ASN A  93
ILE A  92
 None
 1.06A 2h4jA-3x37A:
undetectable		 2h4jA-3x37A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 3x37 ZYRO0C14696P
(Zygosaccharomyce
s
rouxii) 		4 / 5 VAL A  73
VAL A  81
ASP A  77
SER A  15
 None
 1.32A 2x45A-3x37A:
undetectable		 2x45A-3x37A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 3x37 MITOCHONDRIAL
MORPHOGENESIS
PROTEIN SLD7
(Zygosaccharomyce
s
rouxii) 		4 / 8 TYR B  47
VAL B  89
SER B  79
TYR B  16
 GOL  B 202 ( 4.5A)
None
None
None
 1.12A 2y05A-3x37B:
undetectable
2y05B-3x37B:
undetectable		 2y05A-3x37B:
15.50
2y05B-3x37B:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 3x37 MITOCHONDRIAL
MORPHOGENESIS
PROTEIN SLD7
ZYRO0C14696P
(Zygosaccharomyce
s
rouxii) 		4 / 8 ARG A  48
ASP A 115
LEU B  53
PRO B  54
 None
 1.11A 3jq7B-3x37A:
undetectable		 3jq7B-3x37A:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 3x37 ZYRO0C14696P
(Zygosaccharomyce
s
rouxii) 		3 / 3 PHE A  85
SER A  38
SER A  40
 None
 0.95A 3ufgB-3x37A:
undetectable		 3ufgB-3x37A:
16.94