SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zbi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3zbi TRAO PROTEIN
(Escherichia
coli) 		4 / 7 PHE B 955
VAL B1006
GLY B1007
VAL B 944
 None
 0.85A 1t88A-3zbiB:
undetectable		 1t88A-3zbiB:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 3zbi TRAF PROTEIN
TRAO PROTEIN
(Escherichia
coli) 		4 / 7 SER A 886
THR B 974
LEU B 975
TRP B 997
 None
 1.15A 3arrA-3zbiA:
undetectable		 3arrA-3zbiA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 3zbi TRAF PROTEIN
(Escherichia
coli) 		5 / 10 VAL A 889
ILE A 820
THR A 816
VAL A 767
VAL A 787
 None
 0.91A 3me6A-3zbiA:
undetectable		 3me6A-3zbiA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 3zbi TRAF PROTEIN
(Escherichia
coli) 		5 / 9 VAL A 889
ILE A 820
THR A 816
VAL A 767
VAL A 787
 None
 0.86A 3me6C-3zbiA:
undetectable		 3me6C-3zbiA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 3zbi TRAF PROTEIN
(Escherichia
coli) 		5 / 9 VAL A 889
ILE A 820
THR A 816
VAL A 767
VAL A 787
 None
 1.03A 3me6D-3zbiA:
undetectable		 3me6D-3zbiA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3zbi TRAF PROTEIN
(Escherichia
coli) 		5 / 9 GLY A 835
LEU A 755
ASP A 756
LEU A 877
ILE A 791
 None
 1.43A 3wdmA-3zbiA:
undetectable		 3wdmA-3zbiA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3zbi TRAF PROTEIN
(Escherichia
coli) 		5 / 6 SER A 852
ASP A 856
ILE A 849
THR A 857
PHE A 854
 None
 1.44A 4acbC-3zbiA:
undetectable		 4acbC-3zbiA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 3zbi TRAO PROTEIN
(Escherichia
coli) 		4 / 8 GLU B 973
GLU B 996
LYS B 995
ARG B1009
 None
 1.06A 4bqfB-3zbiB:
undetectable		 4bqfB-3zbiB:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 3zbi TRAF PROTEIN
(Escherichia
coli) 		4 / 6 GLY A 829
ASP A 883
PRO A 834
ARG A 801
 None
 1.25A 4lajA-3zbiA:
undetectable
4lajB-3zbiA:
undetectable		 4lajA-3zbiA:
21.11
4lajB-3zbiA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3zbi TRAF PROTEIN
(Escherichia
coli) 		4 / 4 ILE A 873
ASP A 838
ARG A 846
THR A 876
 None
 1.38A 4nx6A-3zbiA:
undetectable		 4nx6A-3zbiA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_1
(DIHYDROFOLATE
REDUCTASE)		 3zbi TRAF PROTEIN
(Escherichia
coli) 		4 / 4 ILE A 873
ASP A 838
ARG A 846
THR A 876
 None
 1.37A 4nx7A-3zbiA:
undetectable		 4nx7A-3zbiA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 3zbi TRAF PROTEIN
TRAO PROTEIN
(Escherichia
coli;
Escherichia
coli) 		5 / 12 GLY A 897
THR A 816
ASP A 894
LEU A 739
ILE B1034
 None
 1.23A 4pghB-3zbiA:
undetectable		 4pghB-3zbiA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_A_H98A501_1
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3zbi TRAF PROTEIN
TRAO PROTEIN
(Escherichia
coli;
Escherichia
coli) 		4 / 4 ASP A 883
SER B 968
SER B 970
ASN A 826
 None
 1.47A 6iblA-3zbiA:
0.0		 6iblA-3zbiA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_1
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3zbi TRAF PROTEIN
TRAO PROTEIN
(Escherichia
coli;
Escherichia
coli) 		4 / 4 ASP A 883
SER B 968
SER B 970
ASN A 826
 None
 1.45A 6iblB-3zbiA:
0.0		 6iblB-3zbiA:
19.85