SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zbq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR6_A_DM2A2002_1
(ACRB)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		5 / 9 SER A 158
GLN A 121
SER A 129
GLY A 282
ILE A 240
 None
 1.50A 2dr6A-3zbqA:
undetectable		 2dr6A-3zbqA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		3 / 3 TYR A  32
GLY A  13
PHE A  11
 None
GDP  A 999 (-3.6A)
None
 0.71A 2m2pB-3zbqA:
undetectable		 2m2pB-3zbqA:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_A_PFNA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		4 / 5 SER A 129
TYR A 102
PHE A 151
VAL A 154
 None
 1.31A 2x7hA-3zbqA:
5.4		 2x7hA-3zbqA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1372_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		4 / 5 SER A 129
TYR A 102
PHE A 151
VAL A 154
 None
 1.31A 2x7hB-3zbqA:
2.8		 2x7hB-3zbqA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		3 / 3 GLY A  14
ASP A  34
SER A  36
 GDP  A 999 (-3.3A)
GDP  A 999 ( 4.4A)
None
 0.59A 3brfA-3zbqA:
undetectable		 3brfA-3zbqA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		5 / 11 ASN A 281
VAL A 131
ILE A 285
LEU A 148
PHE A 151
 None
 1.25A 3fl9C-3zbqA:
undetectable		 3fl9C-3zbqA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		5 / 11 ILE A 182
VAL A 101
VAL A 130
HIS A  27
ILE A   9
 None
 1.22A 3rf4A-3zbqA:
undetectable
3rf4C-3zbqA:
undetectable		 3rf4A-3zbqA:
17.76
3rf4C-3zbqA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		5 / 11 HIS A  27
ILE A   9
ILE A 182
VAL A 101
VAL A 130
 None
 1.19A 3rf4B-3zbqA:
undetectable
3rf4C-3zbqA:
undetectable		 3rf4B-3zbqA:
17.76
3rf4C-3zbqA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		5 / 11 ALA A  77
ILE A  52
GLY A  13
ILE A  85
ILE A  81
 None
None
GDP  A 999 (-3.6A)
None
None
 1.09A 3s53B-3zbqA:
undetectable		 3s53B-3zbqA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		5 / 12 ILE A 132
ILE A 182
VAL A 185
LEU A 186
ILE A   9
 GDP  A 999 (-4.1A)
None
None
None
None
 1.30A 3w67D-3zbqA:
undetectable		 3w67D-3zbqA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BWL_C_MN9C1297_0
(N-ACETYLNEURAMINATE
LYASE)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		5 / 10 ILE A  81
LEU A  80
THR A 111
GLY A 109
GLY A  13
 None
None
None
GDP  A 999 (-3.5A)
GDP  A 999 (-3.6A)
 1.27A 4bwlC-3zbqA:
undetectable		 4bwlC-3zbqA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		5 / 11 GLY A 113
VAL A 117
GLN A 121
MET A 162
PHE A 151
 None
 1.47A 4j4vA-3zbqA:
undetectable		 4j4vA-3zbqA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		4 / 7 SER A 144
GLY A 106
ALA A 107
THR A 111
 None
GDP  A 999 (-3.4A)
GDP  A 999 (-3.8A)
None
 0.86A 4r1zB-3zbqA:
undetectable		 4r1zB-3zbqA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		4 / 6 PHE A  11
PHE A  23
TYR A  26
HIS A  24
 None
 1.22A 4uciA-3zbqA:
undetectable		 4uciA-3zbqA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		4 / 7 PHE A  11
PHE A  23
TYR A  26
HIS A  24
 None
 1.30A 4uciB-3zbqA:
undetectable		 4uciB-3zbqA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVG_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		5 / 12 GLY A  16
GLU A  21
GLY A  20
GLY A  14
GLY A  13
 None
None
None
GDP  A 999 (-3.3A)
GDP  A 999 (-3.6A)
 0.86A 4yvgA-3zbqA:
undetectable		 4yvgA-3zbqA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		5 / 11 VAL A 178
GLN A 175
GLY A  16
GLY A  13
ASN A  39
 GDP  A 999 (-4.2A)
GDP  A 999 (-3.7A)
None
GDP  A 999 (-3.6A)
None
 1.37A 4zvmA-3zbqA:
5.1
4zvmB-3zbqA:
5.4		 4zvmA-3zbqA:
17.46
4zvmB-3zbqA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		4 / 5 ILE A   9
LEU A  22
HIS A 167
VAL A 130
 None
 1.19A 5jmnB-3zbqA:
undetectable		 5jmnB-3zbqA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		3 / 3 HIS A  41
LYS A  40
PHE A  17
 None
 1.24A 5klaA-3zbqA:
undetectable		 5klaA-3zbqA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		4 / 7 PHE A 151
VAL A 154
ILE A 112
THR A 150
 None
 0.89A 5vkqA-3zbqA:
undetectable
5vkqD-3zbqA:
undetectable		 5vkqA-3zbqA:
10.80
5vkqD-3zbqA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		4 / 7 THR A 150
PHE A 151
VAL A 154
ILE A 112
 None
 0.90A 5vkqA-3zbqA:
undetectable
5vkqB-3zbqA:
undetectable		 5vkqA-3zbqA:
10.80
5vkqB-3zbqA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		4 / 8 THR A 150
PHE A 151
VAL A 154
ILE A 112
 None
 0.88A 5vkqB-3zbqA:
undetectable
5vkqC-3zbqA:
undetectable		 5vkqB-3zbqA:
10.80
5vkqC-3zbqA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		4 / 7 THR A 150
PHE A 151
VAL A 154
ILE A 112
 None
 0.89A 5vkqC-3zbqA:
undetectable
5vkqD-3zbqA:
undetectable		 5vkqC-3zbqA:
10.80
5vkqD-3zbqA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_0
(STIE PROTEIN)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		5 / 12 GLY A  16
GLY A  14
ILE A 132
GLU A  21
ILE A 182
 None
GDP  A 999 (-3.3A)
GDP  A 999 (-4.1A)
None
None
 0.96A 6ectA-3zbqA:
undetectable		 6ectA-3zbqA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 3zbq PHIKZ039
(Pseudomonas
virus
phiKZ) 		5 / 12 GLY A  16
GLY A  14
ILE A 132
GLU A  21
ILE A 182
 None
GDP  A 999 (-3.3A)
GDP  A 999 (-4.1A)
None
None
 0.93A 6ecxA-3zbqA:
3.1		 6ecxA-3zbqA:
21.01