SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zc1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)
3zc1 AFTRAX
(Archaeoglobus
fulgidus)
5 / 12 PHE A 108
VAL A  82
ALA A  86
ILE A  85
ILE A  54
None
0.99A 1epbA-3zc1A:
undetectable
1epbA-3zc1A:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)
3zc1 AFTRAX
(Archaeoglobus
fulgidus)
5 / 12 PHE A 108
VAL A  82
ALA A  86
ILE A  85
ILE A  54
None
0.95A 1epbB-3zc1A:
undetectable
1epbB-3zc1A:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)
3zc1 AFTRAX
(Archaeoglobus
fulgidus)
4 / 6 GLU A 118
LEU A 119
VAL A 141
MET A 142
None
1.05A 1hk1A-3zc1A:
2.9
1hk1A-3zc1A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZGW_A_ADNA1301_1
(BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)
3zc1 AFTRAX
(Archaeoglobus
fulgidus)
4 / 7 ARG A   9
GLU A  11
ALA A  16
ALA A  15
None
1.08A 2zgwA-3zc1A:
undetectable
2zgwA-3zc1A:
22.78