SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zcj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 3zcj CAGL
(Helicobacter
pylori) 		3 / 3 ALA A 199
HIS A 200
VAL A 203
 MLY  A 195 ( 3.7A)
None
MLY  A 202 ( 3.3A)
 0.39A 1lqtB-3zcjA:
undetectable		 1lqtB-3zcjA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 3zcj CAGL
(Helicobacter
pylori) 		3 / 3 ALA A 199
HIS A 200
VAL A 203
 MLY  A 195 ( 3.7A)
None
MLY  A 202 ( 3.3A)
 0.39A 1lquB-3zcjA:
undetectable		 1lquB-3zcjA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3zcj CAGL
(Helicobacter
pylori) 		4 / 8 LEU A  82
TYR A 163
PHE A  86
TYR A  34
 MLY  A  83 ( 4.2A)
None
None
None
 1.34A 3po7A-3zcjA:
undetectable		 3po7A-3zcjA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 3zcj CAGL
(Helicobacter
pylori) 		4 / 5 ASP A 212
ASP A  97
ASN A 206
GLU A 209
 MLY  A 149 ( 4.1A)
PEG  A1232 (-3.0A)
PEG  A1232 ( 4.9A)
None
 1.37A 3vywD-3zcjA:
undetectable		 3vywD-3zcjA:
23.90