SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zco'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 3zco REGULATORY PROTEIN
SIR3
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 902
GLU A 905
LEU A 860
ILE A 855
LEU A 923
 None
 1.00A 1errB-3zcoA:
undetectable		 1errB-3zcoA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 3zco REGULATORY PROTEIN
SIR3
(Saccharomyces
cerevisiae) 		4 / 5 GLU A 947
SER A 951
PRO A 948
SER A 949
 None
 1.34A 4k17B-3zcoA:
undetectable		 4k17B-3zcoA:
14.89