SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zd1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)
3zd1 COMPLEMENT FACTOR
H-RELATED PROTEIN 2

(Homo
sapiens)
3 / 3 GLU A 129
ALA A 151
SER A 154
None
0.56A 1errB-3zd1A:
undetectable
1errB-3zd1A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)
3zd1 COMPLEMENT FACTOR
H-RELATED PROTEIN 2

(Homo
sapiens)
5 / 12 ILE A 142
THR A 143
VAL A 156
ILE A 172
PRO A 134
EDO  A1257 (-4.7A)
None
None
None
None
1.13A 3kpdB-3zd1A:
undetectable
3kpdB-3zd1A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)
3zd1 COMPLEMENT FACTOR
H-RELATED PROTEIN 2

(Homo
sapiens)
4 / 6 GLU A 220
LYS A 204
PHE A 221
PRO A 247
None
1.45A 6fgdA-3zd1A:
undetectable
6fgdA-3zd1A:
13.94