SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zdn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 7 TYR A 273
GLU A 263
TRP A 262
PHE A 275
 None
 1.44A 1b2iA-3zdnA:
undetectable		 1b2iA-3zdnA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 5 GLU A 226
ARG A  77
ASP A 458
LEU A 310
 None
FAD  A1487 (-3.7A)
None
None
 1.07A 1n13B-3zdnA:
undetectable
1n13C-3zdnA:
undetectable		 1n13B-3zdnA:
12.50
1n13C-3zdnA:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 8 ALA A 406
LEU A 405
GLY A 355
GLY A 368
 None
 0.85A 1rukH-3zdnA:
undetectable
1rukL-3zdnA:
undetectable		 1rukH-3zdnA:
18.79
1rukL-3zdnA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 8 MET A 233
ASP A 468
SER A 100
HIS A 172
 None
 1.33A 2bteA-3zdnA:
undetectable		 2bteA-3zdnA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 8 MET A 233
ASP A 468
SER A 100
HIS A 172
 None
 1.30A 2bteD-3zdnA:
undetectable		 2bteD-3zdnA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 5 LEU A 363
ALA A 366
TRP A 353
LEU A 379
 None
 1.25A 2oaxA-3zdnA:
undetectable		 2oaxA-3zdnA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 5 LEU A 207
ARG A 204
ALA A 152
ILE A 192
 None
 0.99A 2qhfA-3zdnA:
undetectable		 2qhfA-3zdnA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 7 ASP A 458
LEU A 310
GLU A 226
ARG A  77
 None
None
None
FAD  A1487 (-3.7A)
 0.98A 2qqdA-3zdnA:
undetectable
2qqdE-3zdnA:
0.2		 2qqdA-3zdnA:
9.59
2qqdE-3zdnA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		5 / 12 LEU A 310
GLY A 333
LEU A 313
ALA A 332
GLY A 444
 None
 0.96A 2vmyA-3zdnA:
undetectable		 2vmyA-3zdnA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 5 SER A 465
ARG A 464
GLY A 462
TRP A 463
 None
 1.37A 2y7kB-3zdnA:
undetectable		 2y7kB-3zdnA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		5 / 12 ILE A 467
GLY A  76
GLY A  48
ALA A 470
ASP A  72
 FAD  A1487 (-3.7A)
FAD  A1487 (-3.3A)
FAD  A1487 (-3.6A)
FAD  A1487 (-3.3A)
None
 1.07A 2yvlD-3zdnA:
2.3		 2yvlD-3zdnA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 8 SER A 223
PHE A 431
PHE A 466
LEU A 461
 None
None
FAD  A1487 (-4.8A)
None
 0.92A 3m0wE-3zdnA:
undetectable
3m0wF-3zdnA:
undetectable
3m0wG-3zdnA:
0.3
3m0wH-3zdnA:
0.4		 3m0wE-3zdnA:
10.55
3m0wF-3zdnA:
10.55
3m0wG-3zdnA:
10.55
3m0wH-3zdnA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_2
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		3 / 3 SER A  80
SER A  81
HIS A 378
 None
 0.81A 3mzeA-3zdnA:
undetectable		 3mzeA-3zdnA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA502_1
(CHITINASE)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 4 TRP A 463
GLY A 235
TRP A 231
ALA A 232
 None
 1.41A 3wqvA-3zdnA:
undetectable		 3wqvA-3zdnA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 5 TRP A 463
GLY A 235
TRP A 231
ALA A 232
 None
 1.37A 3wqwA-3zdnA:
undetectable		 3wqwA-3zdnA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		5 / 12 GLY A  47
GLY A  51
VAL A  44
PHE A 275
ALA A 258
 FAD  A1487 (-4.2A)
None
None
None
None
 1.17A 4a6eA-3zdnA:
undetectable		 4a6eA-3zdnA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		3 / 3 ARG A  71
ASP A 392
GLN A 390
 FAD  A1487 (-4.3A)
None
None
 0.80A 4azsA-3zdnA:
2.3		 4azsA-3zdnA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 5 ASN A 284
ALA A 289
GLY A 451
ASP A 458
 None
 0.80A 4n48A-3zdnA:
undetectable		 4n48A-3zdnA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 7 LEU A 210
LEU A 149
ARG A 150
LEU A 153
 None
 0.80A 4wg0B-3zdnA:
undetectable
4wg0C-3zdnA:
undetectable		 4wg0B-3zdnA:
5.14
4wg0C-3zdnA:
5.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 7 LEU A 149
ARG A 150
LEU A 153
LEU A 210
 None
 0.73A 4wg0L-3zdnA:
undetectable
4wg0M-3zdnA:
undetectable		 4wg0L-3zdnA:
5.14
4wg0M-3zdnA:
5.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 7 ALA A  61
ARG A 476
GLY A 474
GLU A 473
 None
 0.96A 5bs8A-3zdnA:
undetectable
5bs8B-3zdnA:
undetectable
5bs8C-3zdnA:
undetectable		 5bs8A-3zdnA:
23.67
5bs8B-3zdnA:
20.04
5bs8C-3zdnA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 7 ALA A  61
ARG A 476
GLY A 474
GLU A 473
 None
 1.00A 5btdA-3zdnA:
undetectable
5btdB-3zdnA:
undetectable
5btdC-3zdnA:
undetectable		 5btdA-3zdnA:
23.67
5btdB-3zdnA:
20.04
5btdC-3zdnA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 6 ALA A  61
ARG A 476
GLY A 474
GLU A 473
 None
 0.92A 5btgA-3zdnA:
undetectable
5btgB-3zdnA:
undetectable
5btgC-3zdnA:
undetectable		 5btgA-3zdnA:
23.67
5btgB-3zdnA:
20.04
5btgC-3zdnA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_B_032B401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 4 CYH A 277
PHE A 275
ILE A  43
GLY A  46
 None
None
None
FAD  A1487 (-3.5A)
 1.48A 5hesB-3zdnA:
undetectable		 5hesB-3zdnA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		6 / 12 GLY A 430
GLY A 436
VAL A 438
THR A 218
GLY A 217
GLY A 216
 FAD  A1487 ( 4.1A)
None
None
None
None
None
 1.46A 5koxA-3zdnA:
10.8		 5koxA-3zdnA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		5 / 12 GLY A 355
ILE A 356
TYR A 139
THR A 138
LEU A 149
 None
 0.91A 5nz0A-3zdnA:
undetectable		 5nz0A-3zdnA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 5 GLN A  17
ASP A   5
SER A   3
ARG A  73
 None
 1.39A 5w4zA-3zdnA:
undetectable		 5w4zA-3zdnA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 4 ARG A  56
GLU A 264
GLU A 105
ARG A 108
 None
 1.24A 6fk2A-3zdnA:
undetectable		 6fk2A-3zdnA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 3zdn MONOAMINE OXIDASE N
(Aspergillus
niger) 		4 / 4 ARG A 108
GLU A 105
GLU A 264
ARG A  56
 None
 1.24A 6fk2A-3zdnA:
undetectable		 6fk2A-3zdnA:
14.94