SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zeu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T46_A_STIA3_2
(HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 7 VAL B  90
VAL B 325
ARG B  49
CYH B  10
 None
None
None
AGS  B1342 ( 4.5A)
 1.16A 1t46A-3zeuB:
undetectable		 1t46A-3zeuB:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 5 CYH B  10
PRO B 327
THR B  55
THR B  13
 AGS  B1342 ( 4.5A)
CL  B1338 (-4.1A)
None
None
 0.97A 1ymxB-3zeuB:
undetectable		 1ymxB-3zeuB:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		5 / 12 GLY B   5
TYR B  78
GLY B  91
ILE B  17
ALA B 306
 None
 1.07A 2plwA-3zeuB:
undetectable		 2plwA-3zeuB:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 8 ALA B 266
ALA B 293
SER B 270
ALA B 271
 None
None
None
ADP  B1343 ( 4.1A)
 0.82A 2vh3B-3zeuB:
undetectable		 2vh3B-3zeuB:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 8 VAL B 311
ILE B 143
VAL B 145
GLY B 149
 None
 0.73A 3hjoB-3zeuB:
undetectable		 3hjoB-3zeuB:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		3 / 3 HIS B 111
HIS B 115
MET B 112
 ZN  B1339 ( 3.2A)
ZN  B1339 ( 3.3A)
AGS  B1342 (-3.2A)
 1.00A 3mihA-3zeuB:
undetectable		 3mihA-3zeuB:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		5 / 9 ILE B 305
LEU B 121
ARG B   2
LEU B  63
GLY B  23
 None
 1.42A 3nxuB-3zeuB:
undetectable		 3nxuB-3zeuB:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		3 / 3 HIS B 111
GLY B 302
ILE B 305
 ZN  B1339 ( 3.2A)
None
None
 0.60A 4k50A-3zeuB:
undetectable		 4k50A-3zeuB:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		3 / 3 HIS B 111
GLY B 302
ILE B 305
 ZN  B1339 ( 3.2A)
None
None
 0.64A 4k50I-3zeuB:
undetectable		 4k50I-3zeuB:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 6 SER B   9
GLY B 163
ASP B 167
GLY B 268
 AGS  B1342 ( 4.9A)
ADP  B1343 (-3.3A)
ADP  B1343 (-2.9A)
AGS  B1342 (-3.1A)
 0.88A 4koeA-3zeuB:
undetectable
4koeB-3zeuB:
undetectable
4koeC-3zeuB:
undetectable		 4koeA-3zeuB:
23.53
4koeB-3zeuB:
23.53
4koeC-3zeuB:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 7 SER B   9
GLY B 163
ASP B 167
GLY B 268
 AGS  B1342 ( 4.9A)
ADP  B1343 (-3.3A)
ADP  B1343 (-2.9A)
AGS  B1342 (-3.1A)
 0.86A 4koeA-3zeuB:
undetectable
4koeB-3zeuB:
undetectable
4koeD-3zeuB:
undetectable		 4koeA-3zeuB:
23.53
4koeB-3zeuB:
23.53
4koeD-3zeuB:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		3 / 3 ASP B 300
TRP B 329
SER B 136
 ZN  B1339 ( 2.5A)
None
AGS  B1342 (-2.9A)
 1.05A 4lrhA-3zeuB:
undetectable		 4lrhA-3zeuB:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 7 THR B  79
THR B 299
LEU B  29
ASN B  27
 None
AGS  B1342 (-4.1A)
None
None
 1.11A 4pfjA-3zeuB:
undetectable		 4pfjA-3zeuB:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		5 / 11 ALA B 165
GLY B 137
GLY B 138
ALA B 161
SER B 157
 None
ADP  B1343 (-3.5A)
AGS  B1342 (-3.2A)
None
None
 0.89A 4qw1K-3zeuB:
undetectable
4qw1L-3zeuB:
undetectable		 4qw1K-3zeuB:
21.96
4qw1L-3zeuB:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 6 GLY B 163
ASP B 167
GLY B 268
SER B   9
 ADP  B1343 (-3.3A)
ADP  B1343 (-2.9A)
AGS  B1342 (-3.1A)
AGS  B1342 ( 4.9A)
 0.84A 4z53A-3zeuB:
undetectable
4z53B-3zeuB:
undetectable		 4z53A-3zeuB:
19.05
4z53B-3zeuB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 7 GLY B 163
ASP B 167
GLY B 268
SER B   9
 ADP  B1343 (-3.3A)
ADP  B1343 (-2.9A)
AGS  B1342 (-3.1A)
AGS  B1342 ( 4.9A)
 0.86A 4z53A-3zeuB:
undetectable
4z53B-3zeuB:
undetectable		 4z53A-3zeuB:
19.05
4z53B-3zeuB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 8 PRO B 178
GLY B 180
PRO B 181
ASP B 167
 None
AGS  B1342 (-3.4A)
AGS  B1342 (-3.8A)
ADP  B1343 (-2.9A)
 0.92A 5kf8A-3zeuB:
undetectable		 5kf8A-3zeuB:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 8 PRO B 178
GLY B 180
PRO B 181
ASP B 167
 None
AGS  B1342 (-3.4A)
AGS  B1342 (-3.8A)
ADP  B1343 (-2.9A)
 0.98A 5kgpA-3zeuB:
undetectable		 5kgpA-3zeuB:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 8 PRO B 178
GLY B 180
PRO B 181
ASP B 167
 None
AGS  B1342 (-3.4A)
AGS  B1342 (-3.8A)
ADP  B1343 (-2.9A)
 0.96A 5kgpB-3zeuB:
undetectable		 5kgpB-3zeuB:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 8 ILE B 305
VAL B   3
ALA B 319
THR B 318
 None
 0.78A 5og9A-3zeuB:
undetectable		 5og9A-3zeuB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 7 VAL B 145
ILE B 143
VAL B 264
ALA B 132
 None
 0.67A 5osrA-3zeuB:
undetectable		 5osrA-3zeuB:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_0
(ADENOSYLHOMOCYSTEINA
SE)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		5 / 12 ASP B 300
HIS B  51
LEU B  88
GLY B  81
HIS B 111
 ZN  B1339 ( 2.5A)
None
None
None
ZN  B1339 ( 3.2A)
 1.34A 6exiD-3zeuB:
undetectable		 6exiD-3zeuB:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		5 / 12 THR B 258
GLY B 259
LEU B 255
THR B 146
GLY B 147
 None
 1.04A 6gngA-3zeuB:
2.5		 6gngA-3zeuB:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 8 HIS B  51
HIS B 110
GLU B   7
ASP B 300
 None
None
None
ZN  B1339 ( 2.5A)
 1.05A 6mn4B-3zeuB:
undetectable		 6mn4B-3zeuB:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 8 HIS B  51
HIS B 110
GLU B   7
ASP B 300
 None
None
None
ZN  B1339 ( 2.5A)
 0.95A 6mn4C-3zeuB:
undetectable		 6mn4C-3zeuB:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP
(Salmonella
enterica) 		4 / 8 HIS B  51
HIS B 110
GLU B   7
ASP B 300
 None
None
None
ZN  B1339 ( 2.5A)
 1.03A 6mn4D-3zeuB:
undetectable		 6mn4D-3zeuB:
23.51