SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zf4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_1
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 3zf4 DUTPASE
(Staphylococcus
virus
80alpha) 		3 / 3 ARG A 134
ARG A  64
ILE A 129
 None
 0.72A 1uobA-3zf4A:
undetectable		 1uobA-3zf4A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 3zf4 DUTPASE
(Staphylococcus
virus
80alpha) 		3 / 3 ASP A  28
ARG A  64
ASP A  24
 None
 0.88A 1vptA-3zf4A:
undetectable		 1vptA-3zf4A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 3zf4 DUTPASE
(Staphylococcus
virus
80alpha) 		5 / 10 TYR A  27
ILE A 140
MET A  16
LEU A  88
VAL A  49
 None
None
None
DUP  A 777 (-4.6A)
None
 1.16A 2w98A-3zf4A:
undetectable		 2w98A-3zf4A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)		 3zf4 DUTPASE
(Staphylococcus
virus
80alpha) 		6 / 11 GLY A  83
ALA A  84
ASP A  81
GLY A  59
ILE A 140
VAL A  49
 None
DUP  A 777 (-3.3A)
DUP  A 777 (-3.6A)
None
None
None
 1.39A 4qgiA-3zf4A:
undetectable		 4qgiA-3zf4A:
16.08