SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zfp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 3zfp N-TERMINAL PROTEASE
NPRO
(Pestivirus
H) 		3 / 3 PHE A  33
TYR A  98
PRO A  23
 None
 0.96A 1mcnA-3zfpA:
undetectable
1mcnB-3zfpA:
undetectable
1mcnP-3zfpA:
undetectable		 1mcnA-3zfpA:
20.81
1mcnB-3zfpA:
20.81
1mcnP-3zfpA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3zfp N-TERMINAL PROTEASE
NPRO
(Pestivirus
H) 		5 / 12 PHE A 106
VAL A  83
LEU A  81
ILE A 163
THR A 166
 None
 1.00A 3em0B-3zfpA:
undetectable		 3em0B-3zfpA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN4_A_SC2A1016_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 3zfp N-TERMINAL PROTEASE
NPRO
(Pestivirus
H) 		4 / 4 HIS A 130
GLY A 119
ARG A 120
THR A  44
 None
 1.38A 5nn4A-3zfpA:
0.0		 5nn4A-3zfpA:
9.58