SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zg1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IWH_A_PEMA501_1 (HEMOGLOBIN ALPHA CHAIN)	3zg1	NICKEL AND COBALT RESISTANCE PROTEIN CNRR (Cupriavidus metallidurans)	4 / 6	ALA A 79 LYS A 83 ASP A 86 ALA A 87	None	0.44A	1iwhA-3zg1A: undetectable	1iwhA-3zg1A: 22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MBG_A_ACTA207_0 (FAD-LINKED SULFHYDRYL OXIDASE ALR)	3zg1	NICKEL AND COBALT RESISTANCE PROTEIN CNRR (Cupriavidus metallidurans)	4 / 7	LEU A 112 ARG A 70 THR A 116 ALA A 115	None	1.29A	3mbgA-3zg1A: 2.3 3mbgB-3zg1A: undetectable	3mbgA-3zg1A: 21.26 3mbgB-3zg1A: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WDM_B_ADNB301_1 (4-PHOSPHOPANTOATE--B ETA-ALANINE LIGASE)	3zg1	NICKEL AND COBALT RESISTANCE PROTEIN CNRR (Cupriavidus metallidurans)	5 / 10	ALA A 142 GLY A 146 LEU A 117 LEU A 41 ASP A 40	None	1.14A	3wdmB-3zg1A: undetectable	3wdmB-3zg1A: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WDM_C_ADNC301_1 (4-PHOSPHOPANTOATE--B ETA-ALANINE LIGASE)	3zg1	NICKEL AND COBALT RESISTANCE PROTEIN CNRR (Cupriavidus metallidurans)	5 / 9	ALA A 142 GLY A 146 LEU A 117 LEU A 41 ASP A 40	None	1.11A	3wdmC-3zg1A: undetectable	3wdmC-3zg1A: 22.35

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IWH_A_PEMA501_1","HEMOGLOBIN ALPHA CHAIN","3zg1","NICKEL AND COBALT RESISTANCE PROTEIN CNRR","Cupriavidus metallidurans",4,"ALA A  79;LYS A  83;ASP A  86;ALA A  87","None","0.44A","1iwhA-3zg1A:undetectable","1iwhA-3zg1A:22.29"],["3MBG_A_ACTA207_0","FAD-LINKED SULFHYDRYL OXIDASE ALR","3zg1","NICKEL AND COBALT RESISTANCE PROTEIN CNRR","Cupriavidus metallidurans",4,"LEU A 112;ARG A  70;THR A 116;ALA A 115","None","1.29A","3mbgA-3zg1A:2.3;3mbgB-3zg1A:undetectable","3mbgA-3zg1A:21.26;3mbgB-3zg1A:21.26"],["3WDM_B_ADNB301_1","4-PHOSPHOPANTOATE--BETA-ALANINE LIGASE","3zg1","NICKEL AND COBALT RESISTANCE PROTEIN CNRR","Cupriavidus metallidurans",5,"ALA A 142;GLY A 146;LEU A 117;LEU A  41;ASP A  40","None","1.14A","3wdmB-3zg1A:undetectable","3wdmB-3zg1A:22.35"],["3WDM_C_ADNC301_1","4-PHOSPHOPANTOATE--BETA-ALANINE LIGASE","3zg1","NICKEL AND COBALT RESISTANCE PROTEIN CNRR","Cupriavidus metallidurans",5,"ALA A 142;GLY A 146;LEU A 117;LEU A  41;ASP A  40","None","1.11A","3wdmC-3zg1A:undetectable","3wdmC-3zg1A:22.35"]]