SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zg4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 3zg4 ERFK/YBIS/YCFS/YNHG
(Enterococcus
faecium) 		3 / 3 PRO A 406
ASP A 422
ASP A 390
 None
 0.78A 1sqfA-3zg4A:
undetectable		 1sqfA-3zg4A:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3zg4 ERFK/YBIS/YCFS/YNHG
(Enterococcus
faecium) 		5 / 11 VAL A 407
ALA A 391
LEU A 393
GLY A 419
PHE A 454
 None
 0.86A 3zosA-3zg4A:
undetectable
3zosB-3zg4A:
undetectable		 3zosA-3zg4A:
18.40
3zosB-3zg4A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3zg4 ERFK/YBIS/YCFS/YNHG
(Enterococcus
faecium) 		5 / 9 VAL A 418
GLY A 441
THR A 377
VAL A 347
VAL A 465
 None
 1.25A 5cp4A-3zg4A:
undetectable		 5cp4A-3zg4A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3zg4 ERFK/YBIS/YCFS/YNHG
(Enterococcus
faecium) 		4 / 5 PHE A 382
GLY A 371
ASP A 414
ILE A 413
 None
 0.97A 5ik1A-3zg4A:
undetectable		 5ik1A-3zg4A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 3zg4 ERFK/YBIS/YCFS/YNHG
(Enterococcus
faecium) 		4 / 5 PRO A 378
VAL A 418
GLY A 430
VAL A 347
 None
 1.01A 6ak3B-3zg4A:
undetectable		 6ak3B-3zg4A:
20.33