SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zgb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 6 GLY A 851
TYR A 858
ALA A 856
GLU A 859
 None
 0.93A 1dmaB-3zgbA:
undetectable		 1dmaB-3zgbA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		3 / 3 SER A 476
GLU A 477
GLU A 478
 None
 0.70A 1eqbD-3zgbA:
undetectable		 1eqbD-3zgbA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		3 / 3 SER A 476
GLU A 477
GLU A 478
 None
 0.69A 1eqbB-3zgbA:
undetectable		 1eqbB-3zgbA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 6 LEU A 149
LEU A 693
LEU A 651
LEU A 262
 None
 0.84A 1errA-3zgbA:
2.6		 1errA-3zgbA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 8 LEU A 430
TYR A 273
PRO A 409
MET A 325
 None
 1.01A 1fduB-3zgbA:
undetectable		 1fduB-3zgbA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 12 LEU A 558
TYR A 595
GLY A 594
ILE A 593
LEU A 662
 None
 1.27A 1kglA-3zgbA:
undetectable		 1kglA-3zgbA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 11 GLY A 496
LEU A 509
LEU A 467
LEU A 494
HIS A 466
 None
 1.27A 1mx1B-3zgbA:
undetectable		 1mx1B-3zgbA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 11 GLY A 496
VAL A 505
LEU A 509
LEU A 467
LEU A 494
 None
 1.21A 1mx1B-3zgbA:
undetectable		 1mx1B-3zgbA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 9 LEU A 376
GLY A 370
LEU A 430
LEU A 410
PHE A 433
 None
 1.16A 1nr6A-3zgbA:
undetectable		 1nr6A-3zgbA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 11 PHE A 816
GLY A 789
THR A 861
VAL A 823
ILE A 820
 None
 1.07A 1phgA-3zgbA:
undetectable		 1phgA-3zgbA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 11 SER A  85
CYH A 898
THR A 950
THR A 954
ILE A  94
 None
 1.18A 1pkvA-3zgbA:
undetectable
1pkvB-3zgbA:
undetectable		 1pkvA-3zgbA:
7.44
1pkvB-3zgbA:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 11 ILE A  94
SER A  85
CYH A 898
THR A 950
THR A 954
 None
 1.18A 1pkvA-3zgbA:
undetectable
1pkvB-3zgbA:
undetectable		 1pkvA-3zgbA:
7.44
1pkvB-3zgbA:
7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		3 / 3 LYS A 613
ASP A 799
ASP A 712
 None
 0.98A 2br4D-3zgbA:
undetectable		 2br4D-3zgbA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 12 ASP A 839
GLY A 851
ALA A 835
THR A 778
PHE A 780
 None
 1.04A 2c49A-3zgbA:
undetectable		 2c49A-3zgbA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 12 ASP A 839
GLY A 851
ALA A 835
THR A 778
PHE A 780
 None
 1.08A 2c49A-3zgbA:
undetectable		 2c49A-3zgbA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		3 / 3 ASP A 564
ASP A 597
ASP A 536
 None
SO4  A1970 (-3.3A)
None
 0.72A 2igtA-3zgbA:
undetectable		 2igtA-3zgbA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		3 / 3 ASP A 564
ASP A 597
ASP A 536
 None
SO4  A1970 (-3.3A)
None
 0.73A 2igtB-3zgbA:
undetectable		 2igtB-3zgbA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIP_D_MTXD617_1
(CHAIN A, CRYSTAL
STRUCTURE OF DHFR)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 12 ALA A 306
LEU A 518
SER A 520
ILE A 449
LEU A 553
 None
 1.14A 2oipD-3zgbA:
undetectable		 2oipD-3zgbA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 6 LEU A 685
MET A 240
MET A 313
LEU A 444
 None
 1.34A 2oz7A-3zgbA:
2.6		 2oz7A-3zgbA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 6 MET A 748
ILE A 906
ARG A 907
PRO A 754
 None
 1.36A 2qd3B-3zgbA:
undetectable		 2qd3B-3zgbA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		3 / 3 ARG A 293
GLN A 233
PRO A 232
 None
 0.79A 2qhfA-3zgbA:
undetectable		 2qhfA-3zgbA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 10 PHE A 632
ASP A 166
SER A 652
LEU A 169
GLY A 634
 None
 1.26A 2v0mA-3zgbA:
0.0		 2v0mA-3zgbA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 6 TYR A  33
LEU A 212
LYS A 205
ASP A 204
 None
 1.20A 2w98A-3zgbA:
undetectable
2w98B-3zgbA:
undetectable		 2w98A-3zgbA:
16.89
2w98B-3zgbA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 5 ARG A 227
ASP A 949
ILE A  92
GLU A 948
 None
 1.49A 2xrzA-3zgbA:
undetectable
2xrzB-3zgbA:
undetectable		 2xrzA-3zgbA:
19.36
2xrzB-3zgbA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 12 ILE A 892
ALA A  35
ARG A  17
LEU A 887
LEU A  30
 None
 0.96A 2yqzA-3zgbA:
undetectable		 2yqzA-3zgbA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 11 VAL A 639
THR A 657
ILE A 658
LEU A 662
THR A 692
 None
 1.42A 3bf1C-3zgbA:
2.5
3bf1D-3zgbA:
2.5		 3bf1C-3zgbA:
15.19
3bf1D-3zgbA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 6 THR A 778
GLN A 899
LEU A 842
LEU A 903
 None
 0.98A 3bgdA-3zgbA:
undetectable		 3bgdA-3zgbA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 6 LEU A 410
TYR A 414
LEU A 417
LEU A 434
 None
 1.04A 3f33A-3zgbA:
3.7		 3f33A-3zgbA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 12 ARG A 227
HIS A 918
ILE A  92
ASP A 949
LEU A 947
 None
 1.21A 3lcvB-3zgbA:
undetectable		 3lcvB-3zgbA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 6 GLU A 297
ASP A 510
ASP A 507
LYS A 506
 None
 1.47A 3pocB-3zgbA:
4.9		 3pocB-3zgbA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 8 PHE A 816
PHE A 815
PHE A 792
PHE A 605
 None
 0.81A 3t3sF-3zgbA:
undetectable		 3t3sF-3zgbA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		3 / 3 ARG A 737
PRO A 770
PHE A 736
 None
 1.01A 3thrC-3zgbA:
undetectable		 3thrC-3zgbA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 5 LEU A 782
ILE A 763
ALA A 774
PHE A 736
 None
 1.06A 4dc3B-3zgbA:
undetectable		 4dc3B-3zgbA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 11 LEU A  45
ILE A 919
GLY A  89
ILE A  92
VAL A  57
 None
 0.93A 4q1xA-3zgbA:
undetectable		 4q1xA-3zgbA:
6.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 12 LEU A  45
ILE A 919
GLY A  89
ILE A  92
VAL A  57
 None
 0.91A 4q1xB-3zgbA:
undetectable		 4q1xB-3zgbA:
6.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 10 LEU A  45
ILE A 919
GLY A  89
ILE A  92
VAL A  57
 None
 0.93A 4q1yA-3zgbA:
undetectable		 4q1yA-3zgbA:
6.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 9 LEU A  79
GLY A  80
LEU A 895
VAL A 897
THR A 894
 None
 1.09A 4x3mB-3zgbA:
undetectable		 4x3mB-3zgbA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA617_0
(SERUM ALBUMIN)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		3 / 3 TRP A 580
ARG A 584
LEU A 575
 None
 0.49A 5dbyA-3zgbA:
undetectable		 5dbyA-3zgbA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 9 GLY A 496
LEU A 499
GLN A 544
LEU A 494
LEU A 467
 None
 1.43A 5fhzB-3zgbA:
undetectable		 5fhzB-3zgbA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 7 LEU A  79
THR A 894
ILE A  94
MET A 101
 None
 1.02A 5fxtA-3zgbA:
undetectable		 5fxtA-3zgbA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 6 LEU A 417
LEU A 434
LEU A 431
LEU A 321
 None
 0.66A 5gs4A-3zgbA:
undetectable		 5gs4A-3zgbA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 11 SER A 535
ASP A 536
GLU A 477
TYR A 581
LEU A 488
 None
 1.36A 5jh7B-3zgbA:
undetectable		 5jh7B-3zgbA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 6 THR A 228
ARG A 226
ILE A 952
GLU A 948
 None
 1.20A 5uigA-3zgbA:
4.7		 5uigA-3zgbA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 5 ARG A 855
PHE A 736
LEU A 782
LEU A 842
 None
 1.05A 5veuH-3zgbA:
1.3		 5veuH-3zgbA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		5 / 12 ILE A 278
LEU A 680
THR A 684
LEU A 685
PHE A 675
 None
 1.25A 5xxiA-3zgbA:
undetectable		 5xxiA-3zgbA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11802_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
UL4
RIBOSOMAL PROTEIN
UL15
RIBOSOMAL PROTEIN
EL15)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		3 / 3 ARG A 767
LYS A 561
ARG A 753
 SO4  A1970 (-4.0A)
None
None
 1.49A 6az3C-3zgbA:
0.2
6az3L-3zgbA:
undetectable
6az3M-3zgbA:
undetectable		 6az3C-3zgbA:
6.95
6az3L-3zgbA:
5.68
6az3M-3zgbA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_2
(-)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 4 GLN A 175
THR A 174
HIS A 185
LEU A 181
 None
 1.50A 6f3nB-3zgbA:
undetectable		 6f3nB-3zgbA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA820_0
(GEPHYRIN)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 5 GLU A 616
PRO A 655
THR A 657
GLN A 653
 None
 1.37A 6fgdA-3zgbA:
undetectable		 6fgdA-3zgbA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		3 / 3 PHE A 682
ARG A 683
GLN A 686
 None
 1.15A 6g1pB-3zgbA:
undetectable		 6g1pB-3zgbA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_1
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE
(Flaveria
pringlei) 		4 / 5 GLN A 963
GLU A 109
ASP A 889
ASN A 103
 ASP  A1967 ( 4.2A)
None
None
None
 1.33A 6iftA-3zgbA:
2.1		 6iftA-3zgbA:
14.61