SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zgk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1356_1
(PROSTAGLANDIN
REDUCTASE 2)		 3zgk AVR3A11
(Phytophthora
capsici) 		4 / 8 ILE A  82
TYR A 128
LEU A 106
LEU A 110
 None
 0.71A 2w98B-3zgkA:
undetectable		 2w98B-3zgkA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3zgk AVR3A11
(Phytophthora
capsici) 		4 / 8 VAL A  75
LEU A 110
LEU A 106
ILE A  82
 None
 0.84A 3u5kC-3zgkA:
undetectable		 3u5kC-3zgkA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 3zgk AVR3A11
(Phytophthora
capsici) 		4 / 5 VAL A  75
LEU A 110
LEU A 106
ILE A  82
 None
 0.87A 4a9jA-3zgkA:
undetectable		 4a9jA-3zgkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 3zgk AVR3A11
(Phytophthora
capsici) 		4 / 5 VAL A  75
LEU A 110
LEU A 106
ILE A  82
 None
 0.84A 4a9jB-3zgkA:
undetectable		 4a9jB-3zgkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 3zgk AVR3A11
(Phytophthora
capsici) 		4 / 5 VAL A  75
LEU A 110
LEU A 106
ILE A  82
 None
 0.83A 4a9jC-3zgkA:
undetectable		 4a9jC-3zgkA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3zgk AVR3A11
(Phytophthora
capsici) 		4 / 8 VAL A  75
LEU A 110
LEU A 106
ILE A  82
 None
 0.86A 5y1yA-3zgkA:
undetectable		 5y1yA-3zgkA:
19.20