SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zgx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		4 / 4 THR A 184
LEU A 188
VAL A 191
LEU A 195
 None
 0.66A 1fbmB-3zgxA:
1.5		 1fbmB-3zgxA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		4 / 4 THR A 184
LEU A 188
VAL A 191
LEU A 195
 None
 0.69A 1fbmD-3zgxA:
undetectable		 1fbmD-3zgxA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		4 / 4 THR A 184
LEU A 188
VAL A 191
LEU A 195
 None
 0.56A 1mz9D-3zgxA:
1.7		 1mz9D-3zgxA:
5.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		4 / 8 ASN A  86
ILE A   9
ASP A   7
ARG A   5
 None
 1.01A 2v57A-3zgxA:
undetectable		 2v57A-3zgxA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		4 / 7 SER A 152
VAL A1072
ILE A 149
ASP A 156
 None
 1.07A 2x45B-3zgxA:
undetectable		 2x45B-3zgxA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		4 / 7 SER A 152
VAL A1072
ILE A 149
ASP A 156
 None
 1.07A 2x45C-3zgxA:
undetectable		 2x45C-3zgxA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		4 / 7 SER A 152
VAL A1072
ILE A 149
ASP A 156
 None
 1.23A 3bu1A-3zgxA:
undetectable		 3bu1A-3zgxA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		3 / 3 SER A  19
ASP A  21
ASP A  88
 None
 0.62A 3iv6A-3zgxA:
undetectable		 3iv6A-3zgxA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		4 / 6 PHE A1103
VAL A1146
THR A1153
PHE A1131
 None
 1.29A 3ltwA-3zgxA:
undetectable		 3ltwA-3zgxA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
SEGREGATION AND
CONDENSATION PROTEIN
A
(Bacillus
subtilis;
Bacillus
subtilis) 		3 / 3 THR C  65
VAL C  61
GLU A 183
 None
 0.50A 3v4tA-3zgxC:
undetectable
3v4tD-3zgxC:
undetectable		 3v4tA-3zgxC:
12.41
3v4tD-3zgxC:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		4 / 7 VAL A1115
PHE A1113
PHE A  22
ILE A  40
 None
 0.92A 3zjqA-3zgxA:
undetectable		 3zjqA-3zgxA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		4 / 7 VAL A1115
PHE A1113
PHE A  22
ILE A  40
 None
 0.91A 3zjqB-3zgxA:
undetectable		 3zjqB-3zgxA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		5 / 12 VAL A1072
THR A1036
ARG A 157
SER A1104
PHE A1037
 None
 1.48A 4c49C-3zgxA:
undetectable		 4c49C-3zgxA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		4 / 7 LEU A1116
VAL A1115
LYS A1136
TYR A1138
 None
 1.04A 4lb2A-3zgxA:
undetectable		 4lb2A-3zgxA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		5 / 9 VAL A1146
ILE A  18
VAL A1163
VAL A1159
ALA A  28
 None
 1.25A 4oqrA-3zgxA:
undetectable		 4oqrA-3zgxA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		4 / 6 GLU A1058
PHE A1044
ARG A1049
PHE A1048
 None
 1.29A 4uciA-3zgxA:
undetectable		 4uciA-3zgxA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		3 / 3 LYS A1151
ARG A1150
HIS A1149
 None
 0.89A 4zbrA-3zgxA:
undetectable		 4zbrA-3zgxA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 3zgx SEGREGATION AND
CONDENSATION PROTEIN
A
(Bacillus
subtilis) 		5 / 9 TYR C  44
ILE C  22
LEU C  19
GLU C  52
ARG C  49
 None
 1.43A 5ifuB-3zgxC:
undetectable		 5ifuB-3zgxC:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
(Bacillus
subtilis) 		5 / 12 ALA A1057
ALA A1076
GLN A1077
PHE A1052
LEU A 150
 None
 0.98A 6a5yD-3zgxA:
undetectable		 6a5yD-3zgxA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 3zgx CHROMOSOME PARTITION
PROTEIN SMC
SEGREGATION AND
CONDENSATION PROTEIN
A
(Bacillus
subtilis) 		4 / 5 GLU C  39
HIS A1043
LEU A1051
VAL A1047
 None
 1.21A 6bc9A-3zgxC:
undetectable		 6bc9A-3zgxC:
20.00