SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zh0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 3zh0 PROTOGLOBIN
(Methanosarcina
acetivorans) 		4 / 7 ASN A 126
TYR A  85
ASN A  82
VAL A  89
 None
HEM  A 200 (-4.5A)
None
HEM  A 200 (-4.4A)
 1.36A 1wu8A-3zh0A:
undetectable
1wu8C-3zh0A:
undetectable		 1wu8A-3zh0A:
22.40
1wu8C-3zh0A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3zh0 PROTOGLOBIN
(Methanosarcina
acetivorans) 		4 / 7 TYR A  85
TYR A 141
PRO A 188
TYR A 189
 HEM  A 200 (-4.5A)
None
None
None
 1.01A 3ugrA-3zh0A:
undetectable		 3ugrA-3zh0A:
20.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 3zh0 PROTOGLOBIN
(Methanosarcina
acetivorans) 		6 / 7 TYR A  61
VAL A  64
PHE A  74
VAL A  89
PHE A  93
ILE A 149
 FMT  A 201 (-4.2A)
None
HEM  A 200 (-3.6A)
HEM  A 200 (-4.4A)
FMT  A 201 ( 4.3A)
HEM  A 200 (-4.3A)
 0.63A 3zjqA-3zh0A:
29.3		 3zjqA-3zh0A:
90.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 3zh0 PROTOGLOBIN
(Methanosarcina
acetivorans) 		6 / 7 TYR A  61
VAL A  64
PHE A  74
VAL A  89
PHE A  93
ILE A 149
 FMT  A 201 (-4.2A)
None
HEM  A 200 (-3.6A)
HEM  A 200 (-4.4A)
FMT  A 201 ( 4.3A)
HEM  A 200 (-4.3A)
 0.62A 3zjqB-3zh0A:
29.1		 3zjqB-3zh0A:
90.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 3zh0 PROTOGLOBIN
(Methanosarcina
acetivorans) 		4 / 4 TYR A 105
THR A 178
VAL A  32
ILE A  42
 None
 1.13A 4jx1F-3zh0A:
undetectable		 4jx1F-3zh0A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 3zh0 PROTOGLOBIN
(Methanosarcina
acetivorans) 		3 / 3 LYS A 125
ARG A 122
HIS A 121
 HEM  A 200 (-4.1A)
None
None
 1.19A 4zbrA-3zh0A:
2.1		 4zbrA-3zh0A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 3zh0 PROTOGLOBIN
(Methanosarcina
acetivorans) 		5 / 12 ASP A 129
ARG A  92
LEU A 184
ALA A 177
ILE A 149
 None
HEM  A 200 (-4.6A)
None
None
HEM  A 200 (-4.3A)
 0.92A 5vc0A-3zh0A:
undetectable		 5vc0A-3zh0A:
16.94