SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zh7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 3zh7 PROTEIN E
(Haemophilus
influenzae) 		3 / 3 TYR A  81
ARG A  92
GLN A 118
 None
 0.82A 1tw4A-3zh7A:
2.6		 1tw4A-3zh7A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3zh7 PROTEIN E
(Haemophilus
influenzae) 		4 / 7 THR A 138
LEU A 140
THR A 135
LEU A 134
 None
EDO  A1154 ( 4.0A)
None
None
 0.75A 4z90A-3zh7A:
undetectable
4z90B-3zh7A:
undetectable
4z90C-3zh7A:
undetectable
4z90D-3zh7A:
undetectable
4z90E-3zh7A:
undetectable		 4z90A-3zh7A:
21.90
4z90B-3zh7A:
21.90
4z90C-3zh7A:
21.90
4z90D-3zh7A:
21.90
4z90E-3zh7A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3zh7 PROTEIN E
(Haemophilus
influenzae) 		4 / 8 THR A 138
LEU A 140
THR A 135
LEU A 134
 None
EDO  A1154 ( 4.0A)
None
None
 0.77A 4z90F-3zh7A:
undetectable
4z90G-3zh7A:
undetectable
4z90H-3zh7A:
undetectable
4z90I-3zh7A:
undetectable
4z90J-3zh7A:
undetectable		 4z90F-3zh7A:
21.90
4z90G-3zh7A:
21.90
4z90H-3zh7A:
21.90
4z90I-3zh7A:
21.90
4z90J-3zh7A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 3zh7 PROTEIN E
(Haemophilus
influenzae) 		3 / 3 LYS A  95
ASP A  69
ILE A  65
 EDO  A1154 (-2.6A)
None
None
 0.82A 5kc4E-3zh7A:
undetectable		 5kc4E-3zh7A:
22.81