SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zhc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3zhc PHYTASE
(Citrobacter
braakii) 		4 / 7 ARG A  63
VAL A  83
ALA A 105
LEU A 104
 None
 0.86A 1pthA-3zhcA:
undetectable		 1pthA-3zhcA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3zhc PHYTASE
(Citrobacter
braakii) 		4 / 7 ARG A  63
VAL A  83
ALA A 105
LEU A 104
 None
 0.85A 1pthB-3zhcA:
undetectable		 1pthB-3zhcA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 3zhc PHYTASE
(Citrobacter
braakii) 		3 / 3 ARG A 158
ILE A 152
TRP A 210
 None
 1.03A 1qomA-3zhcA:
undetectable		 1qomA-3zhcA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 3zhc PHYTASE
(Citrobacter
braakii) 		3 / 3 ARG A 158
ILE A 152
TRP A 210
 None
 1.14A 2nodB-3zhcA:
undetectable		 2nodB-3zhcA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3zhc PHYTASE
(Citrobacter
braakii) 		5 / 12 LEU A 221
ASP A 324
GLU A 218
GLY A  18
HIS A  17
 None
 1.38A 2zj0A-3zhcA:
undetectable		 2zj0A-3zhcA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3zhc PHYTASE
(Citrobacter
braakii) 		4 / 7 THR A  33
PHE A 172
LEU A 189
LEU A 216
 None
 0.86A 3bgdB-3zhcA:
undetectable		 3bgdB-3zhcA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3zhc PHYTASE
(Citrobacter
braakii) 		5 / 12 LEU A 221
ASP A 324
GLU A 218
GLY A  18
HIS A  17
 None
 1.40A 3ce6A-3zhcA:
undetectable		 3ce6A-3zhcA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 3zhc PHYTASE
(Citrobacter
braakii) 		5 / 12 LEU A 221
ASP A 324
GLU A 218
GLY A  18
HIS A  17
 None
 1.41A 3ce6C-3zhcA:
undetectable		 3ce6C-3zhcA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3zhc PHYTASE
(Citrobacter
braakii) 		3 / 3 ARG A 158
ILE A 152
TRP A 210
 None
 1.07A 3e7iB-3zhcA:
undetectable		 3e7iB-3zhcA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_2
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT
LIGHT CHAIN OF
ANTIBODY FAB
FRAGMENT)		 3zhc PHYTASE
(Citrobacter
braakii) 		4 / 5 GLN A 257
ILE A 144
LEU A 256
PHE A 253
 None
 1.26A 3ls4L-3zhcA:
undetectable		 3ls4L-3zhcA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3zhc PHYTASE
(Citrobacter
braakii) 		3 / 3 ARG A 158
ILE A 152
TRP A 210
 None
 0.98A 3nw2A-3zhcA:
undetectable		 3nw2A-3zhcA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3zhc PHYTASE
(Citrobacter
braakii) 		3 / 3 ARG A 158
ILE A 152
TRP A 210
 None
 1.00A 3nw2B-3zhcA:
undetectable		 3nw2B-3zhcA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3zhc PHYTASE
(Citrobacter
braakii) 		3 / 3 LYS A 338
ASP A 345
ARG A 339
 None
 0.87A 5jwaA-3zhcA:
undetectable
5jwaH-3zhcA:
undetectable		 5jwaA-3zhcA:
21.09
5jwaH-3zhcA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3zhc PHYTASE
(Citrobacter
braakii) 		5 / 12 ILE A 299
VAL A  12
LEU A 297
VAL A 294
ILE A 290
 None
 0.95A 5mugA-3zhcA:
undetectable		 5mugA-3zhcA:
19.67