SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zhp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 3zhp CALCIUM-BINDING
PROTEIN 39-LIKE
(Homo
sapiens) 		5 / 12 MET A 258
LEU A 262
ASN A 260
LEU A 305
LEU A 294
 None
 1.40A 1nhzA-3zhpA:
undetectable		 1nhzA-3zhpA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 3zhp CALCIUM-BINDING
PROTEIN 39-LIKE
(Homo
sapiens) 		3 / 3 PRO A 289
PHE A 280
LYS A 286
 None
 1.05A 3bjwG-3zhpA:
undetectable		 3bjwG-3zhpA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3zhp CALCIUM-BINDING
PROTEIN 39-LIKE
(Homo
sapiens) 		5 / 9 PHE A 165
VAL A 198
PHE A 169
ILE A 209
PHE A 187
 None
 1.37A 3t3rC-3zhpA:
undetectable		 3t3rC-3zhpA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3zhp CALCIUM-BINDING
PROTEIN 39-LIKE
(Homo
sapiens) 		4 / 8 TYR A 118
LEU A  73
TYR A  74
VAL A  18
 None
 0.97A 4l1xA-3zhpA:
undetectable		 4l1xA-3zhpA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 3zhp CALCIUM-BINDING
PROTEIN 39-LIKE
(Homo
sapiens) 		4 / 6 LEU A 257
ASN A 254
LEU A 229
ILE A 236
 None
 1.16A 4okxA-3zhpA:
undetectable		 4okxA-3zhpA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 3zhp CALCIUM-BINDING
PROTEIN 39-LIKE
(Homo
sapiens) 		4 / 8 ILE A 290
PHE A 277
LEU A 255
LEU A 301
 None
 0.93A 4qopC-3zhpA:
undetectable		 4qopC-3zhpA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 3zhp CALCIUM-BINDING
PROTEIN 39-LIKE
(Homo
sapiens) 		4 / 6 LEU A 191
ASP A 238
GLU A 234
ILE A 150
 None
 1.09A 4xi3C-3zhpA:
undetectable		 4xi3C-3zhpA:
23.19