SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zi1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 3zi1 GLYOXALASE
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 7 ASP A  64
GLU A  63
GLU A  70
GLU A  35
 None
 1.12A 1knyA-3zi1A:
undetectable
1knyB-3zi1A:
undetectable		 1knyA-3zi1A:
23.82
1knyB-3zi1A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3zi1 GLYOXALASE
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 6 TYR A 177
ILE A 253
PHE A  -2
ARG A   4
 None
 1.47A 1oniA-3zi1A:
undetectable
1oniC-3zi1A:
undetectable		 1oniA-3zi1A:
17.82
1oniC-3zi1A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 3zi1 GLYOXALASE
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		5 / 11 TRP A 155
ILE A 253
LEU A 245
LEU A 217
LEU A 214
 None
 1.29A 2a15A-3zi1A:
undetectable		 2a15A-3zi1A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3zi1 GLYOXALASE
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		5 / 12 ALA A 119
ILE A  89
PHE A  86
GLY A 200
ALA A 198
 None
 1.04A 3lbdA-3zi1A:
undetectable		 3lbdA-3zi1A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3zi1 GLYOXALASE
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		3 / 3 ASP A 136
ASN A 180
PHE A   9
 None
 0.78A 5jglB-3zi1A:
undetectable		 5jglB-3zi1A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 3zi1 GLYOXALASE
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		4 / 5 HIS A  34
GLU A  63
LEU A 232
VAL A 240
 None
None
EDO  A1281 ( 3.9A)
None
 1.21A 6bc9A-3zi1A:
undetectable		 6bc9A-3zi1A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 3zi1 GLYOXALASE
DOMAIN-CONTAINING
PROTEIN 4
(Homo
sapiens) 		5 / 12 ALA A 119
PHE A 125
LEU A  27
ARG A  24
LEU A  71
 None
 1.21A 6ew0G-3zi1A:
undetectable		 6ew0G-3zi1A:
14.24