SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zif'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 12 LEU M 248
ASN M 245
LEU M 244
THR M 334
PHE M 260
 None
 1.44A 1a28A-3zifM:
undetectable		 1a28A-3zifM:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 12 LEU M 248
ASN M 245
LEU M 247
THR M 334
PHE M 260
 None
 1.47A 1a28A-3zifM:
undetectable		 1a28A-3zifM:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 12 TYR A 661
TYR A 667
TYR A 876
LEU A 615
LEU A 674
 None
 1.39A 1fmlA-3zifA:
undetectable		 1fmlA-3zifA:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RK3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 12 VAL A 716
SER A 719
CYH A 825
VAL A 728
LEU A 697
 None
 1.45A 1rk3A-3zifA:
undetectable		 1rk3A-3zifA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 7 TYR M 299
THR M 212
GLU M 306
THR M 286
 None
 1.22A 1tv8B-3zifM:
undetectable		 1tv8B-3zifM:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_SAMB293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 12 TYR M 314
ALA M 289
ARG M 297
TYR M 220
ILE M 195
 None
 1.50A 1xvaB-3zifM:
undetectable		 1xvaB-3zifM:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 10 PHE M 260
PHE M 239
ILE M 250
GLY M 249
THR M 337
 None
 1.12A 1z11C-3zifM:
undetectable		 1z11C-3zifM:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 10 PHE M 260
PHE M 239
ILE M 250
GLY M 249
THR M 337
 None
 1.10A 1z11D-3zifM:
undetectable		 1z11D-3zifM:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 7 ARG A 347
ASP A 669
ARG A 827
ASP A 298
 None
 1.20A 2e5dA-3zifA:
undetectable
2e5dB-3zifA:
undetectable		 2e5dA-3zifA:
20.72
2e5dB-3zifA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 7 ASP A 298
ARG A 347
ASP A 669
ARG A 827
 None
 1.19A 2e5dA-3zifA:
undetectable
2e5dB-3zifA:
undetectable		 2e5dA-3zifA:
20.72
2e5dB-3zifA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 6 ARG A 831
SER A 840
GLY A 842
ARG A 636
 None
 1.15A 2f7fA-3zifA:
undetectable		 2f7fA-3zifA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 6 PHE A 752
ARG A 347
GLY A 670
ARG A 827
 None
 1.20A 2f7fA-3zifA:
undetectable		 2f7fA-3zifA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_B_RBFB202_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 11 GLY A 663
ASN A 552
ARG A 548
PHE A 659
GLU A 334
 None
 1.29A 2fl5A-3zifA:
2.8
2fl5B-3zifA:
undetectable
2fl5F-3zifA:
undetectable		 2fl5A-3zifA:
12.99
2fl5B-3zifA:
13.30
2fl5F-3zifA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 6 PRO M 353
LEU M  86
ARG M 443
GLY M 447
 None
 1.22A 2hs2B-3zifM:
undetectable		 2hs2B-3zifM:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 3zif HEXON PROTEIN
PENTON PROTEIN
(Bovine
mastadenovirus
B;
Bovine
mastadenovirus
B) 		4 / 8 LEU A 312
ARG M 443
ARG M 445
VAL A 897
 None
 1.06A 2qd2A-3zifA:
undetectable		 2qd2A-3zifA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 8 PRO M 383
SER M 426
VAL M 345
GLY M 344
 None
 0.93A 2qd3A-3zifM:
undetectable		 2qd3A-3zifM:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		3 / 3 LEU A 443
PRO A 444
LEU A 447
 None
 0.47A 2qd5B-3zifA:
undetectable		 2qd5B-3zifA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 12 SER A 218
THR A 265
ALA A 286
ILE A 454
ARG A 276
 None
 1.43A 2qm9B-3zifA:
undetectable		 2qm9B-3zifA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3zif PIX
(Bovine
mastadenovirus
B) 		3 / 3 ARG N  64
GLY N  62
SER N  41
 None
 0.61A 2xctB-3zifN:
undetectable		 2xctB-3zifN:
11.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 12 VAL A 716
SER A 719
CYH A 825
VAL A 728
LEU A 697
 None
 1.43A 2zlcA-3zifA:
undetectable		 2zlcA-3zifA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 10 GLY A 670
ASP A 669
THR A 648
LEU A 643
THR A 641
 None
 1.32A 3bexA-3zifA:
undetectable
3bexB-3zifA:
undetectable		 3bexA-3zifA:
13.75
3bexB-3zifA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 11 GLY A 670
ASP A 669
THR A 648
LEU A 643
THR A 641
 None
 1.32A 3bexC-3zifA:
undetectable
3bexD-3zifA:
undetectable		 3bexC-3zifA:
13.75
3bexD-3zifA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 11 THR A 648
LEU A 643
THR A 641
GLY A 670
ASP A 669
 None
 1.32A 3bexE-3zifA:
undetectable
3bexF-3zifA:
undetectable		 3bexE-3zifA:
13.75
3bexF-3zifA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 11 GLY A 670
ASP A 669
THR A 648
LEU A 643
THR A 641
 None
 1.31A 3bf1A-3zifA:
undetectable
3bf1B-3zifA:
undetectable		 3bf1A-3zifA:
13.75
3bf1B-3zifA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 11 GLY A 670
ASP A 669
THR A 648
LEU A 643
THR A 641
 None
 1.34A 3bf1C-3zifA:
undetectable
3bf1D-3zifA:
undetectable		 3bf1C-3zifA:
13.75
3bf1D-3zifA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 11 THR A 648
LEU A 643
THR A 641
GLY A 670
ASP A 669
 None
 1.30A 3bf1C-3zifA:
undetectable
3bf1D-3zifA:
undetectable		 3bf1C-3zifA:
13.75
3bf1D-3zifA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 11 GLY A 670
ASP A 669
THR A 648
LEU A 643
THR A 641
 None
 1.33A 3bf1E-3zifA:
undetectable
3bf1F-3zifA:
undetectable		 3bf1E-3zifA:
13.75
3bf1F-3zifA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 11 THR A 648
LEU A 643
THR A 641
GLY A 670
ASP A 669
 None
 1.33A 3bf1E-3zifA:
undetectable
3bf1F-3zifA:
undetectable		 3bf1E-3zifA:
13.75
3bf1F-3zifA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		3 / 3 PHE A 754
CYH A 825
PHE A 823
 None
 1.09A 3cr5X-3zifA:
undetectable		 3cr5X-3zifA:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		3 / 3 LEU A 443
PRO A 444
LEU A 447
 None
 0.46A 3hcrA-3zifA:
undetectable		 3hcrA-3zifA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 3zif HEXON PROTEIN
PENTON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 8 SER A 629
TYR A 616
LEU M  98
PRO M  97
 None
 1.13A 3jq7B-3zifA:
undetectable		 3jq7B-3zifA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		3 / 3 LYS A 706
ARG A 679
ASP A 489
 None
 0.98A 3o7wA-3zifA:
undetectable		 3o7wA-3zifA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 7 PHE A 834
LEU A 860
ASN A 631
ILE A 683
 None
 0.99A 3rfmA-3zifA:
undetectable		 3rfmA-3zifA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		3 / 3 TYR A 673
LEU A 755
ARG A 827
 None
 0.69A 3sufB-3zifA:
undetectable		 3sufB-3zifA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 9 PHE M 260
PHE M 239
ILE M 250
GLY M 249
THR M 337
 None
 1.11A 3t3rB-3zifM:
undetectable		 3t3rB-3zifM:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3zif PIX
(Bovine
mastadenovirus
B) 		3 / 3 PRO N  71
ASP N  25
GLU N  77
 None
 0.74A 3v4tC-3zifN:
undetectable		 3v4tC-3zifN:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT3_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 12 VAL A 716
SER A 719
CYH A 825
VAL A 728
LEU A 697
 None
 1.42A 3vt3A-3zifA:
undetectable		 3vt3A-3zifA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 12 LEU A 860
LEU A 847
ALA A 633
ALA A 854
TYR A 853
 None
 1.14A 3vw7A-3zifA:
undetectable		 3vw7A-3zifA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		3 / 3 LEU A 443
PRO A 444
LEU A 447
 None
 0.47A 3w1wB-3zifA:
undetectable		 3w1wB-3zifA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		3 / 3 ARG A 508
ARG A 347
ASP A 669
 None
 0.95A 3wipG-3zifA:
undetectable
3wipH-3zifA:
undetectable		 3wipG-3zifA:
12.40
3wipH-3zifA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 8 ARG A 297
GLU A 647
LYS A 644
ARG A 646
 None
 1.23A 4bqfB-3zifA:
undetectable		 4bqfB-3zifA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 5 PHE M 260
ILE M 250
GLY M 249
THR M 337
 None
 0.87A 4ejjC-3zifM:
undetectable		 4ejjC-3zifM:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		3 / 3 ASP A 108
ARG A 516
ASP A 519
 None
 0.80A 4fp9A-3zifA:
undetectable		 4fp9A-3zifA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3zif PIX
(Bovine
mastadenovirus
B) 		4 / 7 LEU N  75
PRO N  38
SER N  41
VAL N  23
 None
 1.25A 4klrA-3zifN:
undetectable		 4klrA-3zifN:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		3 / 3 ARG A 104
HIS A 521
SER A 574
 None
 0.81A 4mjwA-3zifA:
undetectable
4mjwB-3zifA:
undetectable		 4mjwA-3zifA:
20.11
4mjwB-3zifA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		3 / 3 SER A 574
ARG A 104
HIS A 521
 None
 0.85A 4mjwA-3zifA:
undetectable
4mjwB-3zifA:
undetectable		 4mjwA-3zifA:
20.11
4mjwB-3zifA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 8 PRO M 383
SER M 426
VAL M 345
GLY M 344
 None
 0.84A 4mk4A-3zifM:
undetectable		 4mk4A-3zifM:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 11 GLY A 652
PHE A 659
ASP A 550
SER A 662
TYR A 661
 None
 1.39A 4rtrA-3zifA:
undetectable		 4rtrA-3zifA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YOA_A_017A100_1
(HIV-1 PROTEASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 6 ASN A 122
THR A 262
PRO A 263
THR A 265
 None
 1.15A 4yoaA-3zifA:
undetectable		 4yoaA-3zifA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 6 TYR A 337
LYS A 527
GLU A 334
TYR A 306
 None
 1.26A 4z4cA-3zifA:
undetectable		 4z4cA-3zifA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 4 TYR A 337
LYS A 527
GLU A 334
TYR A 306
 None
 1.30A 4z4iA-3zifA:
0.0		 4z4iA-3zifA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 5 PHE A 904
HIS A 858
LEU A 860
PRO A 903
 None
 1.39A 5csyB-3zifA:
undetectable		 5csyB-3zifA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 3zif PVIII
(Bovine
mastadenovirus
B) 		4 / 5 GLY R  22
PRO R  15
THR R  12
GLN R  14
 None
 1.14A 5h5fA-3zifR:
undetectable		 5h5fA-3zifR:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 6 LYS A 549
SER A 574
VAL A 575
ASP A  75
 None
 1.22A 5hesA-3zifA:
undetectable		 5hesA-3zifA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 12 PRO A 288
GLY A 217
THR A 213
SER A 123
TYR A 121
 None
 1.13A 5hfjA-3zifA:
undetectable		 5hfjA-3zifA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_C_SAMC301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 12 PRO A 288
GLY A 217
THR A 213
SER A 123
TYR A 121
 None
 1.13A 5hfjC-3zifA:
undetectable		 5hfjC-3zifA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 12 PRO A 288
GLY A 217
THR A 213
SER A 123
TYR A 121
 None
 1.16A 5hfjG-3zifA:
undetectable		 5hfjG-3zifA:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 5 TYR A 337
LYS A 527
GLU A 334
TYR A 306
 None
 1.33A 5js1A-3zifA:
undetectable		 5js1A-3zifA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 4 LEU A 303
ARG A 508
ILE A 522
PHE A 296
 None
 0.94A 5kirB-3zifA:
undetectable		 5kirB-3zifA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 10 LEU A 536
GLY A 317
GLY A 893
ILE A 531
ALA A 324
 None
 1.05A 5l0zB-3zifA:
undetectable		 5l0zB-3zifA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 12 PHE M 239
ILE M 262
MET M 173
VAL M 139
CYH M 235
 None
 1.38A 5mlmA-3zifM:
undetectable		 5mlmA-3zifM:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		6 / 9 ALA A 530
ILE A 531
TYR A 899
ILE A 895
ALA A 316
LEU A 315
 None
 1.46A 5mvmA-3zifA:
undetectable
5mvmE-3zifA:
undetectable		 5mvmA-3zifA:
6.84
5mvmE-3zifA:
6.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 8 PHE A 834
LEU A 860
ASN A 631
ILE A 683
 None
 0.91A 5mzjA-3zifA:
undetectable		 5mzjA-3zifA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 5 TYR M  51
ALA M 100
GLN M  91
THR M  88
 None
 1.32A 5n0wB-3zifM:
undetectable		 5n0wB-3zifM:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		3 / 3 TYR A 100
SER A  98
TRP A 354
 None
 1.00A 5n8jA-3zifA:
undetectable		 5n8jA-3zifA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		3 / 3 TYR A 100
SER A  98
TRP A 354
 None
 0.99A 5n8jD-3zifA:
undetectable		 5n8jD-3zifA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		4 / 6 ASP A 162
LEU A 163
PHE A 253
TYR A 175
 None
 1.05A 5nooC-3zifA:
undetectable		 5nooC-3zifA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 11 ILE M 170
ILE M 250
GLY M 249
GLY M 339
THR M 201
 None
 0.87A 5twjD-3zifM:
undetectable		 5twjD-3zifM:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		 3zif HEXON PROTEIN
PENTON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 9 ASP M 354
GLN M 450
GLY M 447
GLY M 448
ALA A 906
 None
 1.35A 5v3cA-3zifM:
undetectable		 5v3cA-3zifM:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 3zif HEXON PROTEIN
(Bovine
mastadenovirus
B) 		3 / 3 GLU A 865
ASP A 867
PRO A 868
 None
 0.71A 6berA-3zifA:
undetectable		 6berA-3zifA:
1.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA820_0
(GEPHYRIN)		 3zif PIX
(Bovine
mastadenovirus
B) 		4 / 5 GLU N  61
PRO N  38
THR N  27
GLN N  69
 None
 1.49A 6fgdA-3zifN:
undetectable		 6fgdA-3zifN:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 3zif PENTON PROTEIN
(Bovine
mastadenovirus
B) 		5 / 12 PHE M 239
ILE M 262
MET M 173
VAL M 139
CYH M 235
 None
 1.39A 6gsdA-3zifM:
undetectable		 6gsdA-3zifM:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3zif PVIII
(Bovine
mastadenovirus
B) 		3 / 3 ASN R  52
PRO R   8
GLN R  25
 None
 0.80A 6jnhA-3zifR:
undetectable		 6jnhA-3zifR:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3zif PVIII
(Bovine
mastadenovirus
B) 		3 / 3 ASN R  52
PRO R   8
GLN R  25
 None
 0.82A 6jogA-3zifR:
undetectable		 6jogA-3zifR:
23.64