SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zig'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QHY_A_CLMA999_0 (CHLORAMPHENICOL PHOSPHOTRANSFERASE)	3zig	SEPF-LIKE PROTEIN (Pyrococcus furiosus)	5 / 12	SER A 103 ILE A 128 ILE A 120 ILE A 76 LEU A 71	None	0.99A	1qhyA-3zigA: undetectable	1qhyA-3zigA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDT_A_VORA506_1 (CHOLESTEROL 24-HYDROXYLASE)	3zig	SEPF-LIKE PROTEIN (Pyrococcus furiosus)	5 / 9	VAL A 119 ILE A 94 ALA A 95 ALA A 102 THR A 101	None	1.25A	3mdtA-3zigA: undetectable	3mdtA-3zigA: 12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NC3_A_ERMA1202_2 (CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562)	3zig	SEPF-LIKE PROTEIN (Pyrococcus furiosus)	4 / 6	THR A 101 LEU A 81 LEU A 90 GLU A 89	None	1.16A	4nc3A-3zigA: undetectable	4nc3A-3zigA: 16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZF8_A_MYTA502_1 (BIFUNCTIONAL P-450/NADPH-P450 REDUCTASE)	3zig	SEPF-LIKE PROTEIN (Pyrococcus furiosus)	4 / 6	VAL A 119 LEU A 64 ILE A 94 ALA A 95	None	0.79A	4zf8A-3zigA: undetectable	4zf8A-3zigA: 10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MFX_A_ACTA701_0 (GENOME POLYPROTEIN)	3zig	SEPF-LIKE PROTEIN (Pyrococcus furiosus)	4 / 5	THR A 60 HIS A 61 ALA A 62 ASP A 63	None	1.33A	5mfxA-3zigA: undetectable	5mfxA-3zigA: 12.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1QHY_A_CLMA999_0","CHLORAMPHENICOL PHOSPHOTRANSFERASE","3zig","SEPF-LIKE PROTEIN","Pyrococcus furiosus",5,"SER A 103;ILE A 128;ILE A 120;ILE A  76;LEU A  71","None","0.99A","1qhyA-3zigA:undetectable","1qhyA-3zigA:18.18"],["3MDT_A_VORA506_1","CHOLESTEROL 24-HYDROXYLASE","3zig","SEPF-LIKE PROTEIN","Pyrococcus furiosus",5,"VAL A 119;ILE A  94;ALA A  95;ALA A 102;THR A 101","None","1.25A","3mdtA-3zigA:undetectable","3mdtA-3zigA:12.35"],["4NC3_A_ERMA1202_2","CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562","3zig","SEPF-LIKE PROTEIN","Pyrococcus furiosus",4,"THR A 101;LEU A  81;LEU A  90;GLU A  89","None","1.16A","4nc3A-3zigA:undetectable","4nc3A-3zigA:16.08"],["4ZF8_A_MYTA502_1","BIFUNCTIONAL P-450\/NADPH-P450 REDUCTASE","3zig","SEPF-LIKE PROTEIN","Pyrococcus furiosus",4,"VAL A 119;LEU A  64;ILE A  94;ALA A  95","None","0.79A","4zf8A-3zigA:undetectable","4zf8A-3zigA:10.96"],["5MFX_A_ACTA701_0","GENOME POLYPROTEIN","3zig","SEPF-LIKE PROTEIN","Pyrococcus furiosus",4,"THR A  60;HIS A  61;ALA A  62;ASP A  63","None","1.33A","5mfxA-3zigA:undetectable","5mfxA-3zigA:12.50"]]