SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zil'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zil AAR187CP
(Eremothecium
gossypii) 		6 / 12 ILE A 359
ALA A 356
TRP A 338
LEU A 397
ALA A 393
LEU A 335
 None
 1.39A 1fm6A-3zilA:
undetectable		 1fm6A-3zilA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zil AAR187CP
(Eremothecium
gossypii) 		6 / 12 ILE A 359
ALA A 356
TRP A 338
LEU A 397
ALA A 393
LEU A 335
 None
 1.44A 1fm9A-3zilA:
undetectable		 1fm9A-3zilA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zil AAR187CP
(Eremothecium
gossypii) 		6 / 12 ILE A 359
ALA A 356
TRP A 338
LEU A 397
ALA A 393
LEU A 335
 None
 1.40A 1k74A-3zilA:
undetectable		 1k74A-3zilA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 3zil AAR187CP
(Eremothecium
gossypii) 		4 / 5 GLU A 375
THR A 418
LEU A 414
LEU A 417
 None
 1.23A 1u18B-3zilA:
undetectable		 1u18B-3zilA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zil AAR187CP
(Eremothecium
gossypii) 		6 / 12 ILE A 359
ALA A 356
TRP A 338
LEU A 397
ALA A 393
LEU A 335
 None
 1.41A 1xdkA-3zilA:
undetectable		 1xdkA-3zilA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zil AAR187CP
(Eremothecium
gossypii) 		6 / 12 ILE A 359
ALA A 356
TRP A 338
LEU A 397
ALA A 393
LEU A 335
 None
 1.41A 1xdkE-3zilA:
undetectable		 1xdkE-3zilA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zil AAR187CP
(Eremothecium
gossypii) 		6 / 12 ILE A 359
ALA A 356
TRP A 338
LEU A 397
ALA A 393
LEU A 335
 None
 1.38A 1xlsA-3zilA:
undetectable		 1xlsA-3zilA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zil AAR187CP
(Eremothecium
gossypii) 		6 / 12 ILE A 359
ALA A 356
TRP A 338
LEU A 397
ALA A 393
LEU A 335
 None
 1.39A 1xlsB-3zilA:
undetectable		 1xlsB-3zilA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zil AAR187CP
(Eremothecium
gossypii) 		6 / 12 ILE A 359
ALA A 356
TRP A 338
LEU A 397
ALA A 393
LEU A 335
 None
 1.39A 1xlsC-3zilA:
undetectable		 1xlsC-3zilA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zil AAR187CP
(Eremothecium
gossypii) 		6 / 12 ILE A 359
ALA A 356
TRP A 338
LEU A 397
ALA A 393
LEU A 335
 None
 1.38A 1xlsD-3zilA:
undetectable		 1xlsD-3zilA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3zil AAR187CP
(Eremothecium
gossypii) 		5 / 8 LYS A 533
LEU A 532
PHE A 495
PHE A 491
LEU A 510
 None
 1.30A 2dyrC-3zilA:
undetectable
2dyrJ-3zilA:
undetectable		 2dyrC-3zilA:
21.81
2dyrJ-3zilA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 3zil AAR187CP
(Eremothecium
gossypii) 		5 / 12 LEU A 405
PHE A 394
ILE A 471
ASN A 470
LEU A 424
 None
 1.07A 2w3mA-3zilA:
undetectable		 2w3mA-3zilA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 3zil AAR187CP
(Eremothecium
gossypii) 		3 / 3 ASP A 275
PHE A 272
LEU A 268
 None
 0.65A 2zi9A-3zilA:
undetectable		 2zi9A-3zilA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 3zil AAR187CP
(Eremothecium
gossypii) 		5 / 12 LEU A 465
PHE A 539
ALA A 514
VAL A 543
VAL A 490
 None
 1.11A 3c6gB-3zilA:
undetectable		 3c6gB-3zilA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 3zil AAR187CP
(Eremothecium
gossypii) 		5 / 12 LEU A 465
PHE A 539
ALA A 514
VAL A 543
VAL A 490
 None
 1.13A 3czhB-3zilA:
undetectable		 3czhB-3zilA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zil AAR187CP
(Eremothecium
gossypii) 		5 / 12 ILE A 471
ILE A 415
LEU A 424
VAL A 512
LEU A 438
 None
 1.12A 3dzuA-3zilA:
undetectable		 3dzuA-3zilA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3zil AAR187CP
(Eremothecium
gossypii) 		4 / 8 ILE A 295
ALA A 299
LEU A 373
ALA A 354
 None
 0.93A 3hrdA-3zilA:
undetectable
3hrdB-3zilA:
undetectable		 3hrdA-3zilA:
23.28
3hrdB-3zilA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 3zil AAR187CP
(Eremothecium
gossypii) 		5 / 12 LEU A 405
PHE A 394
ILE A 471
ASN A 470
LEU A 424
 None
 1.07A 4kebB-3zilA:
undetectable		 4kebB-3zilA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3zil AAR187CP
(Eremothecium
gossypii) 		5 / 7 LYS A 533
LEU A 532
PHE A 495
PHE A 491
LEU A 510
 None
 1.37A 5b3sP-3zilA:
undetectable		 5b3sP-3zilA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 3zil AAR187CP
(Eremothecium
gossypii) 		4 / 8 ILE A 277
LEU A 211
ILE A 210
LEU A 279
 None
 0.86A 5ieoA-3zilA:
undetectable		 5ieoA-3zilA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 3zil AAR187CP
(Eremothecium
gossypii) 		5 / 12 GLY A 399
LYS A 404
ASN A 407
LEU A 463
LEU A 467
 None
 1.28A 5nwwA-3zilA:
undetectable		 5nwwA-3zilA:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zil AAR187CP
(Eremothecium
gossypii) 		6 / 12 ILE A 359
ALA A 356
TRP A 338
LEU A 397
ALA A 393
LEU A 335
 None
 1.28A 5uanA-3zilA:
undetectable		 5uanA-3zilA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3zil AAR187CP
(Eremothecium
gossypii) 		4 / 5 TYR A 515
ARG A 556
THR A 560
LEU A 561
 None
 1.41A 5w97J-3zilA:
undetectable		 5w97J-3zilA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zil AAR187CP
(Eremothecium
gossypii) 		6 / 12 ILE A 359
ALA A 356
TRP A 338
LEU A 397
ALA A 393
LEU A 335
 None
 1.39A 5z12B-3zilA:
undetectable		 5z12B-3zilA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zil AAR187CP
(Eremothecium
gossypii) 		6 / 12 ILE A 359
ALA A 356
TRP A 338
LEU A 397
ALA A 393
LEU A 335
 None
 1.41A 6a5yD-3zilA:
undetectable		 6a5yD-3zilA:
12.37