SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ziu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 9 ALA A 330
TYR A 331
LEU A 329
PHE A 394
TYR A  39
 None
 1.45A 1ru9H-3ziuA:
undetectable
1ru9L-3ziuA:
undetectable		 1ru9H-3ziuA:
15.06
1ru9L-3ziuA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 10 ALA A 330
TYR A 331
LEU A 329
PHE A 394
TYR A  39
 None
 1.46A 1ruaH-3ziuA:
undetectable
1ruaL-3ziuA:
undetectable		 1ruaH-3ziuA:
15.06
1ruaL-3ziuA:
15.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		8 / 8 MET A  43
TYR A  46
ASP A  84
SER A 324
TYR A 327
TYR A 361
HIS A 367
HIS A 371
 LSS  A1638 (-3.9A)
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 ( 3.9A)
LSS  A1638 (-4.8A)
None
LSS  A1638 (-3.8A)
LSS  A1638 (-3.7A)
 0.41A 2bteA-3ziuA:
44.0		 2bteA-3ziuA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		4 / 8 TYR A 327
TYR A  46
HIS A 371
HIS A 367
 LSS  A1638 (-4.8A)
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 (-3.8A)
 0.89A 2bteA-3ziuA:
44.0		 2bteA-3ziuA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		4 / 8 TYR A 361
TYR A  46
HIS A 371
HIS A 367
 None
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 (-3.8A)
 1.21A 2bteA-3ziuA:
44.0		 2bteA-3ziuA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		8 / 8 MET A  43
TYR A  46
ASP A  84
SER A 324
TYR A 327
TYR A 361
HIS A 367
HIS A 371
 LSS  A1638 (-3.9A)
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 ( 3.9A)
LSS  A1638 (-4.8A)
None
LSS  A1638 (-3.8A)
LSS  A1638 (-3.7A)
 0.46A 2bteD-3ziuA:
37.4		 2bteD-3ziuA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		4 / 8 TYR A 327
TYR A  46
HIS A 371
HIS A 367
 LSS  A1638 (-4.8A)
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 (-3.8A)
 0.92A 2bteD-3ziuA:
37.4		 2bteD-3ziuA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		4 / 8 TYR A 361
TYR A  46
HIS A 371
HIS A 367
 None
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 (-3.8A)
 1.33A 2bteD-3ziuA:
37.4		 2bteD-3ziuA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		7 / 7 MET A  43
TYR A  46
ASP A  84
TYR A 327
TYR A 361
HIS A 367
HIS A 371
 LSS  A1638 (-3.9A)
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 (-4.8A)
None
LSS  A1638 (-3.8A)
LSS  A1638 (-3.7A)
 0.46A 2bytA-3ziuA:
43.7		 2bytA-3ziuA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		4 / 7 TYR A 327
TYR A  46
HIS A 371
HIS A 367
 LSS  A1638 (-4.8A)
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 (-3.8A)
 0.87A 2bytA-3ziuA:
43.7		 2bytA-3ziuA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		4 / 7 TYR A 361
TYR A  46
HIS A 371
HIS A 367
 None
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 (-3.8A)
 1.30A 2bytA-3ziuA:
43.7		 2bytA-3ziuA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		7 / 7 MET A  43
TYR A  46
ASP A  84
TYR A 327
TYR A 361
HIS A 367
HIS A 371
 LSS  A1638 (-3.9A)
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 (-4.8A)
None
LSS  A1638 (-3.8A)
LSS  A1638 (-3.7A)
 0.46A 2bytD-3ziuA:
44.4		 2bytD-3ziuA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		4 / 7 TYR A 327
TYR A  46
HIS A 371
HIS A 367
 LSS  A1638 (-4.8A)
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 (-3.8A)
 0.87A 2bytD-3ziuA:
44.4		 2bytD-3ziuA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		4 / 7 TYR A 361
TYR A  46
HIS A 371
HIS A 367
 None
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 (-3.8A)
 1.30A 2bytD-3ziuA:
44.4		 2bytD-3ziuA:
32.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 12 PHE A 260
ARG A 254
GLN A 199
LEU A 170
ILE A 249
 None
None
None
GOL  A1642 (-4.9A)
None
 1.46A 2fj1A-3ziuA:
undetectable		 2fj1A-3ziuA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		4 / 5 SER A 122
THR A  30
ASP A 124
PRO A  80
 None
 1.34A 2hdnB-3ziuA:
2.5
2hdnC-3ziuA:
undetectable
2hdnD-3ziuA:
3.1		 2hdnB-3ziuA:
21.23
2hdnC-3ziuA:
7.18
2hdnD-3ziuA:
21.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		8 / 8 MET A  43
TYR A  46
ASP A  84
SER A 324
TYR A 327
TYR A 361
HIS A 367
HIS A 371
 LSS  A1638 (-3.9A)
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 ( 3.9A)
LSS  A1638 (-4.8A)
None
LSS  A1638 (-3.8A)
LSS  A1638 (-3.7A)
 0.63A 2v0gA-3ziuA:
44.1		 2v0gA-3ziuA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		4 / 8 TYR A 327
TYR A  46
HIS A 371
HIS A 367
 LSS  A1638 (-4.8A)
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 (-3.8A)
 0.90A 2v0gA-3ziuA:
44.1		 2v0gA-3ziuA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		4 / 8 TYR A 361
TYR A  46
HIS A 371
HIS A 367
 None
LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 (-3.8A)
 1.34A 2v0gA-3ziuA:
44.1		 2v0gA-3ziuA:
32.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V0G_D_LEUD1883_0
(AMINOACYL-TRNA
SYNTHETASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 5 TYR A  46
ASP A  84
TYR A 327
TYR A 361
HIS A 367
 LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 (-4.8A)
None
LSS  A1638 (-3.8A)
 0.40A 2v0gD-3ziuA:
43.7		 2v0gD-3ziuA:
32.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 12 ILE A 498
ALA A  40
ILE A 502
MET A 510
MET A 438
 None
 1.34A 2xkwB-3ziuA:
undetectable		 2xkwB-3ziuA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 10 ASP A 384
ARG A 210
PHE A 377
ILE A 143
ILE A 387
 None
 1.43A 3uf8A-3ziuA:
undetectable		 3uf8A-3ziuA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		4 / 8 ARG A 187
LEU A 166
ARG A 254
GLU A  91
 None
 1.12A 3zmdA-3ziuA:
undetectable
3zmdB-3ziuA:
undetectable		 3zmdA-3ziuA:
15.22
3zmdB-3ziuA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 12 ILE A  81
GLU A 366
ILE A 403
GLU A  58
HIS A 367
 None
LSS  A1638 (-3.0A)
LSS  A1638 (-4.2A)
LSS  A1638 (-4.4A)
LSS  A1638 (-3.8A)
 1.19A 4a97B-3ziuA:
2.8
4a97C-3ziuA:
2.9		 4a97B-3ziuA:
18.65
4a97C-3ziuA:
18.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		6 / 7 MET A  43
ASP A  84
SER A 324
GLU A 366
HIS A 367
HIS A 371
 LSS  A1638 (-3.9A)
LSS  A1638 (-3.7A)
LSS  A1638 ( 3.9A)
LSS  A1638 (-3.0A)
LSS  A1638 (-3.8A)
LSS  A1638 (-3.7A)
 0.78A 4aq7A-3ziuA:
29.5		 4aq7A-3ziuA:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AQ7_D_LEUD902_0
(LEUCINE--TRNA LIGASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		8 / 9 MET A  43
ASP A  84
SER A 324
TYR A 327
TYR A 361
GLU A 366
HIS A 367
HIS A 371
 LSS  A1638 (-3.9A)
LSS  A1638 (-3.7A)
LSS  A1638 ( 3.9A)
LSS  A1638 (-4.8A)
None
LSS  A1638 (-3.0A)
LSS  A1638 (-3.8A)
LSS  A1638 (-3.7A)
 0.72A 4aq7D-3ziuA:
40.3		 4aq7D-3ziuA:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 7 ASP A  84
SER A 324
TYR A 361
HIS A 367
HIS A 371
 LSS  A1638 (-3.7A)
LSS  A1638 ( 3.9A)
None
LSS  A1638 (-3.8A)
LSS  A1638 (-3.7A)
 0.66A 4arcA-3ziuA:
40.5		 4arcA-3ziuA:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 7 TYR A  46
ASP A  84
SER A 324
TYR A 361
HIS A 371
 LSS  A1638 (-3.3A)
LSS  A1638 (-3.7A)
LSS  A1638 ( 3.9A)
None
LSS  A1638 (-3.7A)
 0.29A 4arcA-3ziuA:
40.5		 4arcA-3ziuA:
31.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		4 / 8 VAL A 419
TRP A 449
LEU A 119
LEU A 433
 None
 0.92A 4jtrA-3ziuA:
undetectable		 4jtrA-3ziuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 12 ILE A 632
GLN A 583
ILE A 604
ALA A 607
PHE A 635
 None
 1.12A 4rp8C-3ziuA:
undetectable		 4rp8C-3ziuA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 12 TRP A 256
GLU A  91
GLY A  87
LEU A 295
PRO A 294
 None
 1.16A 4uilH-3ziuA:
undetectable
4uilL-3ziuA:
undetectable		 4uilH-3ziuA:
15.05
4uilL-3ziuA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 12 ASN A 492
HIS A 491
ASP A 535
LEU A  72
ILE A 538
 None
 1.39A 5dv4A-3ziuA:
undetectable		 5dv4A-3ziuA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 11 ASP A 384
ARG A 210
PHE A 377
ILE A 143
ILE A 387
 None
 1.44A 5hwcA-3ziuA:
undetectable		 5hwcA-3ziuA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 12 ALA A 153
PHE A 144
THR A 317
ARG A 252
GLN A 253
 None
None
None
GOL  A1642 (-4.1A)
None
 1.43A 5m54B-3ziuA:
1.0		 5m54B-3ziuA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UH6_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		5 / 12 GLN A 115
ASP A  64
ARG A 434
ARG A  68
HIS A  79
 None
 1.26A 5uh6C-3ziuA:
undetectable		 5uh6C-3ziuA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		4 / 8 ARG A 187
ALA A  90
SER A  97
GLY A  49
 None
 0.89A 5v0vA-3ziuA:
undetectable		 5v0vA-3ziuA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3ziu LEUCYL-TRNA
SYNTHETASE
(Mycoplasma
mobile) 		3 / 3 ARG A 434
PHE A  28
ARG A  68
 None
 1.23A 5y9yA-3ziuA:
undetectable		 5y9yA-3ziuA:
19.94