SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zj0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zj0 ACETYLTRANSFERASE
(Oceanicola
granulosus) 		5 / 12 ALA A  47
LEU A  18
ILE A   7
HIS A 154
LEU A 155
 None
 0.99A 1fm6U-3zj0A:
undetectable		 1fm6U-3zj0A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3zj0 ACETYLTRANSFERASE
(Oceanicola
granulosus) 		4 / 8 GLY A 200
ARG A 188
LEU A 190
VAL A 197
 None
 1.01A 1gsfC-3zj0A:
undetectable		 1gsfC-3zj0A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 3zj0 ACETYLTRANSFERASE
(Oceanicola
granulosus) 		3 / 3 TRP A  88
TYR A  50
LEU A  18
 None
 1.07A 1kxhA-3zj0A:
undetectable		 1kxhA-3zj0A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3zj0 ACETYLTRANSFERASE
(Oceanicola
granulosus) 		3 / 3 VAL A  48
ALA A  47
HIS A 135
 None
None
ACO  A1205 (-3.1A)
 0.77A 1q23C-3zj0A:
undetectable		 1q23C-3zj0A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3zj0 ACETYLTRANSFERASE
(Oceanicola
granulosus) 		3 / 3 VAL A  48
ALA A  47
HIS A 135
 None
None
ACO  A1205 (-3.1A)
 0.75A 1q23L-3zj0A:
undetectable		 1q23L-3zj0A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 3zj0 ACETYLTRANSFERASE
(Oceanicola
granulosus) 		3 / 3 ARG A  93
ARG A 118
PRO A 119
 None
 1.11A 2wljA-3zj0A:
undetectable		 2wljA-3zj0A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 3zj0 ACETYLTRANSFERASE
(Oceanicola
granulosus) 		4 / 8 ARG A 141
GLU A  65
GLU A  62
ARG A   8
 None
 1.24A 4bqfB-3zj0A:
undetectable		 4bqfB-3zj0A:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 3zj0 ACETYLTRANSFERASE
(Oceanicola
granulosus) 		5 / 10 ASP A  38
ALA A 115
ILE A 116
GLY A  43
SER A 109
 None
 1.07A 5i6xA-3zj0A:
undetectable		 5i6xA-3zj0A:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3zj0 ACETYLTRANSFERASE
(Oceanicola
granulosus) 		3 / 3 VAL A   5
GLN A 143
CYH A  68
 None
ACO  A1205 (-3.7A)
None
 0.83A 5icxA-3zj0A:
undetectable
5icxE-3zj0A:
undetectable		 5icxA-3zj0A:
16.37
5icxE-3zj0A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zj0 ACETYLTRANSFERASE
(Oceanicola
granulosus) 		5 / 12 ALA A  47
LEU A  18
ILE A   7
HIS A 154
LEU A 155
 None
 0.96A 6a5zL-3zj0A:
undetectable		 6a5zL-3zj0A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 3zj0 ACETYLTRANSFERASE
(Oceanicola
granulosus) 		5 / 10 GLY A  43
ILE A  45
ALA A  47
PRO A  49
HIS A 135
 None
None
None
None
ACO  A1205 (-3.1A)
 0.74A 6e5zA-3zj0A:
undetectable		 6e5zA-3zj0A:
27.00