SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zja'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zja SL3965
(Streptomyces
lividans) 		5 / 12 ALA A  57
ALA A  58
VAL A 113
ILE A 111
LEU A 147
 None
 0.87A 1fm6U-3zjaA:
undetectable		 1fm6U-3zjaA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3zja SL3965
(Streptomyces
lividans) 		3 / 3 HIS A 127
HIS A  98
MET A 105
 CU  A 999 (-3.3A)
CU  A 999 (-3.2A)
CU  A 999 (-2.2A)
 1.00A 3mihA-3zjaA:
undetectable		 3mihA-3zjaA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3zja SL3965
(Streptomyces
lividans) 		5 / 12 ALA A  57
ALA A  58
VAL A 113
ILE A 111
LEU A 147
 None
 0.91A 3oapA-3zjaA:
undetectable		 3oapA-3zjaA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 3zja SL3965
(Streptomyces
lividans) 		4 / 5 VAL A 143
LEU A 159
ILE A  60
VAL A  95
 None
 0.95A 4a9kB-3zjaA:
undetectable		 4a9kB-3zjaA:
18.42