SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zjx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 3zjx EPSILON-TOXIN
(Clostridium
perfringens) 		4 / 7 VAL A 192
TYR A 244
GLU A  74
PRO A  75
 None
 1.30A 3hs4A-3zjxA:
undetectable		 3hs4A-3zjxA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3zjx EPSILON-TOXIN
(Clostridium
perfringens) 		3 / 3 ASN A 136
ASP A 111
ARG A 286
 None
 0.77A 3k13C-3zjxA:
undetectable		 3k13C-3zjxA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3zjx EPSILON-TOXIN
(Clostridium
perfringens) 		4 / 5 ALA A 181
VAL A 179
PHE A 105
ILE A 169
 BOG  A1297 ( 3.9A)
BOG  A1297 (-4.9A)
BOG  A1297 (-3.9A)
None
 0.99A 5of1B-3zjxA:
undetectable		 5of1B-3zjxA:
13.73