SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zk4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 6 LEU A 302
ASP A 304
LEU A 152
HIS A 252
 None
GOL  A 901 ( 4.4A)
None
None
 1.27A 1errB-3zk4A:
undetectable		 1errB-3zk4A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 7 TRP A 351
THR A  77
GLY A 364
LEU A 361
 None
 0.96A 1gtiE-3zk4A:
undetectable		 1gtiE-3zk4A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		5 / 12 GLY A 271
GLY A 515
GLY A 516
HIS A 479
GLY A 345
 None
None
None
FE  A 800 ( 3.4A)
None
 0.81A 1n2xB-3zk4A:
undetectable		 1n2xB-3zk4A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		5 / 12 ILE A 298
GLN A 297
ALA A 276
GLY A 515
GLY A 290
 None
None
None
None
NAG  A 808 ( 4.5A)
 1.11A 1rjdA-3zk4A:
undetectable		 1rjdA-3zk4A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 8 PHE A 270
ALA A 343
LEU A 314
MET A 273
 None
 1.07A 1x8vA-3zk4A:
undetectable		 1x8vA-3zk4A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 7 THR A 401
HIS A 400
GLY A 312
ASP A 313
 None
None
None
MN  A 801 (-2.6A)
 0.84A 2ddwB-3zk4A:
undetectable		 2ddwB-3zk4A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_B_ANWB99_0
(PROTEIN S100-A13)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 8 ALA A 192
VAL A 163
THR A 164
THR A 166
 None
 1.08A 2kotB-3zk4A:
undetectable		 2kotB-3zk4A:
9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 6 THR A 373
ARG A 382
THR A 220
ASP A 173
 None
 1.23A 2okcA-3zk4A:
undetectable		 2okcA-3zk4A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 6 THR A 373
ARG A 382
THR A 220
ASP A 173
 None
 1.29A 2okcB-3zk4A:
undetectable		 2okcB-3zk4A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 8 HIS A 477
ASP A 313
SER A 344
ASP A 362
 MN  A 801 ( 3.3A)
MN  A 801 (-2.6A)
None
None
 1.01A 2p02A-3zk4A:
undetectable		 2p02A-3zk4A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		3 / 3 ASP A 159
THR A 190
PRO A 191
 None
 0.52A 2pynB-3zk4A:
undetectable		 2pynB-3zk4A:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		3 / 3 ASP A 159
THR A 190
PRO A 191
 None
 0.46A 2q64B-3zk4A:
undetectable		 2q64B-3zk4A:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		3 / 3 ASP A 159
THR A 190
PRO A 191
 None
 0.51A 2qakB-3zk4A:
undetectable		 2qakB-3zk4A:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		3 / 3 TYR A 387
GLU A 348
ASP A 362
 None
 0.82A 3bxoA-3zk4A:
undetectable		 3bxoA-3zk4A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		3 / 3 TYR A 387
GLU A 348
ASP A 362
 None
 0.79A 3bxoB-3zk4A:
undetectable		 3bxoB-3zk4A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_A_TOPA200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		5 / 10 LEU A 433
VAL A 267
ALA A 473
ILE A 472
LEU A 550
 None
 1.24A 3fl9A-3zk4A:
undetectable		 3fl9A-3zk4A:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		5 / 12 LEU A 464
TYR A 412
ILE A 415
ALA A 473
PHE A 432
 None
 0.84A 3gwwA-3zk4A:
undetectable		 3gwwA-3zk4A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		3 / 3 ASN A 145
ASP A 173
ARG A 199
 None
 0.89A 3k13C-3zk4A:
undetectable		 3k13C-3zk4A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 7 ILE A 472
VAL A 510
ARG A 483
TYR A 481
 None
 0.73A 3p6hA-3zk4A:
undetectable		 3p6hA-3zk4A:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.43A 3p97C-3zk4A:
undetectable		 3p97C-3zk4A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		3 / 3 HIS A 509
SER A 442
ASN A 490
 None
 0.81A 3s8pB-3zk4A:
undetectable		 3s8pB-3zk4A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		5 / 11 ALA A  27
VAL A  42
VAL A  59
ALA A  63
LEU A 109
 None
 1.04A 3sm2B-3zk4A:
undetectable		 3sm2B-3zk4A:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		3 / 3 ASP A 159
THR A 190
PRO A 191
 None
 0.54A 3tkgD-3zk4A:
undetectable		 3tkgD-3zk4A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 8 THR A 201
ARG A 208
GLY A 368
SER A 363
 None
 0.99A 3tzfB-3zk4A:
2.2		 3tzfB-3zk4A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		5 / 11 ILE A 269
ILE A 431
VAL A 470
LEU A 430
VAL A 422
 None
 1.14A 3w67A-3zk4A:
3.2		 3w67A-3zk4A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		3 / 3 ASP A 350
GLY A 345
TYR A 358
 None
 0.80A 3w9tC-3zk4A:
undetectable		 3w9tC-3zk4A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		3 / 3 ASP A 350
GLY A 345
TYR A 358
 None
 0.80A 3w9tG-3zk4A:
undetectable		 3w9tG-3zk4A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		5 / 12 GLY A 290
PHE A 537
VAL A 511
TYR A 316
LEU A 519
 NAG  A 808 ( 4.5A)
NAG  A 808 (-4.7A)
None
FE  A 800 ( 4.3A)
None
 1.29A 4a83A-3zk4A:
undetectable		 4a83A-3zk4A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		5 / 12 GLY A 516
PHE A 537
VAL A 511
TYR A 316
LEU A 519
 None
NAG  A 808 (-4.7A)
None
FE  A 800 ( 4.3A)
None
 1.48A 4a83A-3zk4A:
undetectable		 4a83A-3zk4A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.46A 4ctjA-3zk4A:
undetectable		 4ctjA-3zk4A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.43A 4ctjC-3zk4A:
undetectable		 4ctjC-3zk4A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 8 SER A  96
ILE A  25
LEU A 122
ILE A  57
 None
 0.87A 4dtaB-3zk4A:
undetectable		 4dtaB-3zk4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		3 / 3 ARG A 208
TRP A 351
GLY A 365
 None
 1.03A 4e7cA-3zk4A:
undetectable		 4e7cA-3zk4A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		5 / 10 ILE A 269
VAL A 512
GLY A 515
VAL A 308
VAL A 268
 None
 1.08A 4j5jB-3zk4A:
undetectable		 4j5jB-3zk4A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 8 HIS A 477
ASP A 313
SER A 344
ASP A 362
 MN  A 801 ( 3.3A)
MN  A 801 (-2.6A)
None
None
 1.12A 4ndnA-3zk4A:
undetectable		 4ndnA-3zk4A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA301_1
(CHITOSANASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 4 ASP A 423
GLY A 260
PRO A 259
GLN A 265
 None
 1.38A 4oltA-3zk4A:
undetectable		 4oltA-3zk4A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		5 / 12 ALA A 434
GLY A 271
PHE A 309
ALA A 517
TYR A 316
 None
None
None
FE  A 800 ( 4.3A)
FE  A 800 ( 4.3A)
 0.97A 4pclA-3zk4A:
undetectable		 4pclA-3zk4A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		3 / 3 HIS A 509
SER A 442
ASN A 490
 None
 0.84A 5cprB-3zk4A:
undetectable		 5cprB-3zk4A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.46A 5e9qA-3zk4A:
undetectable		 5e9qA-3zk4A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.47A 5ec8A-3zk4A:
undetectable		 5ec8A-3zk4A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.46A 5ehgA-3zk4A:
undetectable		 5ehgA-3zk4A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.46A 5eifA-3zk4A:
undetectable		 5eifA-3zk4A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.44A 5eifC-3zk4A:
undetectable		 5eifC-3zk4A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.47A 5ekxB-3zk4A:
undetectable		 5ekxB-3zk4A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.43A 5ikmA-3zk4A:
undetectable		 5ikmA-3zk4A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.45A 5kqsA-3zk4A:
undetectable		 5kqsA-3zk4A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		5 / 12 THR A  77
SER A 363
GLY A 365
ALA A 205
MET A 202
 None
 1.39A 5lf3N-3zk4A:
undetectable		 5lf3N-3zk4A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.42A 5njvA-3zk4A:
undetectable		 5njvA-3zk4A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.44A 5njvB-3zk4A:
undetectable		 5njvB-3zk4A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.43A 5njvC-3zk4A:
undetectable		 5njvC-3zk4A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.45A 5wz2A-3zk4A:
undetectable		 5wz2A-3zk4A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.43A 5wz2B-3zk4A:
undetectable		 5wz2B-3zk4A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		6 / 12 GLY A 274
GLY A 476
GLY A 271
GLY A 516
VAL A 437
ASP A 313
 None
None
None
None
None
MN  A 801 (-2.6A)
 1.47A 5wz2C-3zk4A:
undetectable		 5wz2C-3zk4A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 6 PHE A 118
ILE A  87
GLY A  58
TYR A  91
 None
None
None
NAG  A 920 (-3.7A)
 0.94A 5x5qE-3zk4A:
undetectable		 5x5qE-3zk4A:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJS_A_SALA603_0
(VICILIN-LIKE
ANTIMICROBIAL
PEPTIDES 2-2)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		5 / 11 GLY A 271
MET A 273
TYR A 340
PHE A 327
GLY A 312
 None
 1.49A 5yjsA-3zk4A:
undetectable		 5yjsA-3zk4A:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		5 / 12 LEU A 550
ILE A 431
VAL A 422
LEU A 504
TYR A 500
 None
 1.02A 6djzA-3zk4A:
undetectable		 6djzA-3zk4A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA812_0
(GEPHYRIN)		 3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1
(Lupinus
luteus) 		4 / 6 LYS A 254
PHE A 253
VAL A 338
PRO A 339
 None
 1.37A 6fgdA-3zk4A:
undetectable		 6fgdA-3zk4A:
20.46