SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zks'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3zks XA4813
(Lama
glama) 		6 / 11 PHE D 188
ASN D 233
GLY D 214
THR D 217
ILE D 229
LEU D 238
 None
 1.48A 1z11A-3zksD:
undetectable		 1z11A-3zksD:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3zks XA4813
(Lama
glama) 		6 / 11 PHE D 188
ASN D 233
GLY D 214
THR D 217
ILE D 229
LEU D 238
 None
 1.50A 1z11B-3zksD:
undetectable		 1z11B-3zksD:
11.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CJK_B_ACTB302_0
(IMMUNOGLOBULIN FAB
HEAVY CHAIN)		 3zks XA4813
(Lama
glama) 		3 / 3 TYR D 219
GLY D 225
THR D 228
 None
 0.18A 6cjkB-3zksD:
19.4		 6cjkB-3zksD:
32.30