SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zlc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 3zlc ER-DERIVED VESICLES
PROTEIN ERV41
(Saccharomyces
cerevisiae) 		3 / 3 MET A 276
GLU A 176
ASP A  86
 None
 1.08A 3a25A-3zlcA:
undetectable		 3a25A-3zlcA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3zlc ER-DERIVED VESICLES
PROTEIN ERV41
(Saccharomyces
cerevisiae) 		4 / 7 GLY A 166
GLN A  99
ASP A  70
ILE A  71
 None
 0.93A 3fi0P-3zlcA:
undetectable		 3fi0P-3zlcA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 3zlc ER-DERIVED VESICLES
PROTEIN ERV41
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  80
VAL A  94
ILE A 168
GLY A 166
ILE A  82
 None
 1.09A 3nu5B-3zlcA:
undetectable		 3nu5B-3zlcA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 3zlc ER-DERIVED VESICLES
PROTEIN ERV41
(Saccharomyces
cerevisiae) 		4 / 8 GLN A  87
ASN A 284
ASN A 171
THR A  64
 None
 1.26A 4d1yA-3zlcA:
undetectable
4d1yB-3zlcA:
undetectable		 4d1yA-3zlcA:
19.84
4d1yB-3zlcA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3zlc ER-DERIVED VESICLES
PROTEIN ERV41
(Saccharomyces
cerevisiae) 		4 / 8 PRO A 242
ALA A 250
SER A 289
ASP A  58
 None
 1.07A 4l7iB-3zlcA:
undetectable		 4l7iB-3zlcA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 3zlc ER-DERIVED VESICLES
PROTEIN ERV41
(Saccharomyces
cerevisiae) 		3 / 3 THR A 243
THR A 254
PHE A 208
 None
 0.84A 5cxvA-3zlcA:
undetectable		 5cxvA-3zlcA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 3zlc ER-DERIVED VESICLES
PROTEIN ERV41
(Saccharomyces
cerevisiae) 		5 / 9 LEU A  80
VAL A  94
ILE A 168
GLY A 166
ILE A  82
 None
 1.05A 5kqxB-3zlcA:
undetectable		 5kqxB-3zlcA:
14.05