SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zlp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H79_A_T3A1_1 (THRA PROTEIN)	3zlp	THIOREDOXIN PEROXIDASE (Schistosoma mansoni)	5 / 12	ILE A 18 ALA A 16 ALA A 71 LEU A 93 ILE A 52	None	1.02A	2h79A-3zlpA: undetectable	2h79A-3zlpA: 20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWS_X_T3X500_1 (THYROID HORMONE RECEPTOR BETA)	3zlp	THIOREDOXIN PEROXIDASE (Schistosoma mansoni)	5 / 12	ILE A 18 ALA A 16 ALA A 71 LEU A 93 ILE A 52	None	1.05A	3gwsX-3zlpA: undetectable	3gwsX-3zlpA: 21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OKX_B_SAMB201_0 (YAEB-LIKE PROTEIN RPA0152)	3zlp	THIOREDOXIN PEROXIDASE (Schistosoma mansoni)	3 / 3	LYS A 143 ARG A 147 LYS A 3	None	1.42A	3okxA-3zlpA: undetectable	3okxA-3zlpA: 22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BEE_B_RXMB601_0 (SCAFFOLD PROTEIN D13)	3zlp	THIOREDOXIN PEROXIDASE (Schistosoma mansoni)	5 / 9	GLN A 137 GLU A 51 PHE A 55 PHE A 127 VAL A 149	None	1.30A	6beeA-3zlpA: 0.0 6beeB-3zlpA: 0.0 6beeC-3zlpA: 0.0	6beeA-3zlpA: 17.58 6beeB-3zlpA: 17.58 6beeC-3zlpA: 17.58

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2H79_A_T3A1_1","THRA PROTEIN","3zlp","THIOREDOXIN PEROXIDASE","Schistosoma mansoni",5,"ILE A  18;ALA A  16;ALA A  71;LEU A  93;ILE A  52","None","1.02A","2h79A-3zlpA:undetectable","2h79A-3zlpA:20.94"],["3GWS_X_T3X500_1","THYROID HORMONE RECEPTOR BETA","3zlp","THIOREDOXIN PEROXIDASE","Schistosoma mansoni",5,"ILE A  18;ALA A  16;ALA A  71;LEU A  93;ILE A  52","None","1.05A","3gwsX-3zlpA:undetectable","3gwsX-3zlpA:21.88"],["3OKX_B_SAMB201_0","YAEB-LIKE PROTEIN RPA0152","3zlp","THIOREDOXIN PEROXIDASE","Schistosoma mansoni",3,"LYS A 143;ARG A 147;LYS A   3","None","1.42A","3okxA-3zlpA:undetectable","3okxA-3zlpA:22.39"],["6BEE_B_RXMB601_0","SCAFFOLD PROTEIN D13","3zlp","THIOREDOXIN PEROXIDASE","Schistosoma mansoni",5,"GLN A 137;GLU A  51;PHE A  55;PHE A 127;VAL A 149","None","1.30A","6beeA-3zlpA:0.0;6beeB-3zlpA:0.0;6beeC-3zlpA:0.0","6beeA-3zlpA:17.58;6beeB-3zlpA:17.58;6beeC-3zlpA:17.58"]]