SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zmr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.80A 1grmA-3zmrA:
undetectable		 1grmA-3zmrA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.80A 1grmB-3zmrA:
undetectable		 1grmB-3zmrA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		4 / 6 ALA A 234
LYS A 237
ASP A 241
ALA A 242
 None
 0.28A 1iwhA-3zmrA:
undetectable		 1iwhA-3zmrA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.60A 1jnoA-3zmrA:
undetectable		 1jnoA-3zmrA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.61A 1jnoB-3zmrA:
undetectable		 1jnoB-3zmrA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.71A 1jo3A-3zmrA:
undetectable		 1jo3A-3zmrA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.71A 1jo3B-3zmrA:
undetectable		 1jo3B-3zmrA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.67A 1jo4A-3zmrA:
undetectable		 1jo4A-3zmrA:
3.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.67A 1jo4B-3zmrA:
undetectable		 1jo4B-3zmrA:
3.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.63A 1magA-3zmrA:
undetectable		 1magA-3zmrA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.63A 1magB-3zmrA:
undetectable		 1magB-3zmrA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.58A 1ng8A-3zmrA:
undetectable		 1ng8A-3zmrA:
5.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.58A 1ng8B-3zmrA:
undetectable		 1ng8B-3zmrA:
5.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.83A 1nrmA-3zmrA:
undetectable		 1nrmA-3zmrA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.83A 1nrmB-3zmrA:
undetectable		 1nrmB-3zmrA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.68A 1nruA-3zmrA:
undetectable		 1nruA-3zmrA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ALA A 169
VAL A 210
TRP A 228
 None
 0.68A 1nruB-3zmrA:
undetectable		 1nruB-3zmrA:
2.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 11 ILE A 250
ALA A 293
PHE A 292
LEU A 290
ILE A 247
 None
 1.16A 1uduA-3zmrA:
undetectable		 1uduA-3zmrA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 GLU A 182
THR A 166
LEU A 194
 None
 0.69A 1v8bC-3zmrA:
undetectable		 1v8bC-3zmrA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 12 PRO A 140
ILE A 366
TYR A 129
ILE A 361
VAL A 324
 None
 1.02A 1z9hD-3zmrA:
undetectable		 1z9hD-3zmrA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OIQ_A_STIA1001_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		4 / 5 LEU A 156
VAL A 458
LEU A 413
MET A 151
 None
 1.10A 2oiqA-3zmrA:
undetectable		 2oiqA-3zmrA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OK6_H_BEZH2001_0
(AROMATIC AMINE
DEHYDROGENASE, LARGE
SUBUNIT
AROMATIC AMINE
DEHYDROGENASE, SMALL
SUBUNIT)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 10 LEU A 272
GLN A 316
GLY A 318
ASN A 320
PHE A 323
 None
 1.46A 2ok6A-3zmrA:
undetectable
2ok6H-3zmrA:
undetectable		 2ok6A-3zmrA:
23.49
2ok6H-3zmrA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 12 ASN A 296
GLU A 297
HIS A 371
TYR A 373
GLU A 430
 BGC  A1518 (-2.8A)
BGC  A1518 (-2.6A)
BGC  A1518 ( 4.8A)
BGC  A1518 ( 4.4A)
GLC  A1519 (-2.8A)
 0.50A 2v3dA-3zmrA:
16.0		 2v3dA-3zmrA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_A_TESA339_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 10 ILE A 250
TRP A 276
ASN A 162
VAL A 206
VAL A 246
 None
 1.07A 3burA-3zmrA:
5.9		 3burA-3zmrA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ASN A 162
ASN A 165
GLU A 478
 None
BGC  A1520 (-3.2A)
None
 0.82A 3kpdC-3zmrA:
undetectable		 3kpdC-3zmrA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ASN A 345
ASN A 296
GLU A 369
 EDO  A1516 (-4.6A)
BGC  A1518 (-2.8A)
None
 0.82A 3kpdC-3zmrA:
undetectable		 3kpdC-3zmrA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ASN A 345
ASN A 296
GLU A 369
 EDO  A1516 (-4.6A)
BGC  A1518 (-2.8A)
None
 0.89A 3kpdB-3zmrA:
undetectable		 3kpdB-3zmrA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		4 / 4 LEU A 480
ILE A 380
TYR A 476
TYR A 431
 None
GLC  A1519 ( 3.9A)
XYS  A1524 (-3.9A)
None
 1.35A 3vt7A-3zmrA:
undetectable		 3vt7A-3zmrA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC0_A_MIYA1204_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS B FROM
TRANSPOSON TN1 0)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 12 PHE A 355
ARG A 328
THR A 295
GLN A 342
LEU A 291
 None
 1.33A 4ac0A-3zmrA:
undetectable		 4ac0A-3zmrA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		4 / 5 LEU A 240
ILE A 208
ALA A 238
PHE A 195
 None
 1.08A 4dc3B-3zmrA:
undetectable		 4dc3B-3zmrA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_D_SAMD401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 11 ILE A 250
GLY A 164
ASN A 162
ASN A 249
GLU A 253
 None
 1.48A 4jdsD-3zmrA:
undetectable		 4jdsD-3zmrA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		4 / 8 ASN A 334
ARG A 333
LEU A 290
ILE A 248
 None
 1.06A 4k0bA-3zmrA:
undetectable		 4k0bA-3zmrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 12 VAL A 110
SER A  82
CYH A  80
LEU A  52
ILE A  63
 None
 1.45A 4kukA-3zmrA:
undetectable		 4kukA-3zmrA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 11 LEU A 153
TYR A 245
VAL A 205
ILE A 247
PHE A 367
 None
 1.39A 4lhmA-3zmrA:
undetectable		 4lhmA-3zmrA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 PRO A 209
ASN A 296
HIS A 371
 None
BGC  A1518 (-2.8A)
BGC  A1518 ( 4.8A)
 1.02A 4ma3H-3zmrA:
3.6
4ma3L-3zmrA:
4.3		 4ma3H-3zmrA:
19.29
4ma3L-3zmrA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 12 TYR A 212
VAL A 236
ALA A 235
PHE A 292
VAL A 210
 None
 1.25A 4mm6A-3zmrA:
undetectable		 4mm6A-3zmrA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 11 THR A 484
ALA A 239
GLU A 182
ASP A 473
GLY A 475
 None
None
None
None
EDO  A1517 (-4.4A)
 1.31A 4zjoD-3zmrA:
undetectable		 4zjoD-3zmrA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		4 / 7 ILE A 224
PHE A 216
ILE A 250
GLU A 253
 None
 0.87A 4zzbC-3zmrA:
undetectable
4zzbD-3zmrA:
undetectable		 4zzbC-3zmrA:
22.77
4zzbD-3zmrA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		4 / 6 ILE A 224
PHE A 216
ILE A 250
GLU A 253
 None
 1.00A 4zzcA-3zmrA:
undetectable
4zzcB-3zmrA:
undetectable		 4zzcA-3zmrA:
22.02
4zzcB-3zmrA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		4 / 6 ILE A 224
PHE A 216
ILE A 250
GLU A 253
 None
 0.95A 4zzcB-3zmrA:
1.9
4zzcC-3zmrA:
undetectable		 4zzcB-3zmrA:
22.02
4zzcC-3zmrA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 9 VAL A 236
VAL A 232
ILE A 279
PHE A 292
LEU A 290
 None
 1.39A 5e4dA-3zmrA:
undetectable		 5e4dA-3zmrA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 12 ILE A 428
LEU A 467
ASP A 347
VAL A 348
ALA A 349
 None
None
EDO  A1516 (-3.8A)
None
EDO  A1513 (-3.6A)
 1.05A 5km9B-3zmrA:
undetectable		 5km9B-3zmrA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_1
(PROTEASE E35D-DRV)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 12 LEU A 501
VAL A 458
GLY A 429
ILE A 427
VAL A 463
 None
 1.09A 5kqyA-3zmrA:
undetectable		 5kqyA-3zmrA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZ0_A_ZLDA301_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR ETHR)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 12 GLY A 429
ILE A 428
MET A 151
VAL A 205
LEU A 416
 None
 1.15A 5nz0A-3zmrA:
undetectable		 5nz0A-3zmrA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		5 / 12 PHE A 367
ILE A 427
ILE A 247
LEU A 291
HIS A 338
 None
 1.01A 5uvmB-3zmrA:
undetectable		 5uvmB-3zmrA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ASP A 288
ASP A 204
ASN A 502
 None
 0.67A 6gngB-3zmrA:
undetectable		 6gngB-3zmrA:
22.22