SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3zn8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSL_A_PZIA800_0 (GLUTAMATE RECEPTOR 2)	3zn8	SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN (Sulfolobus solfataricus)	4 / 7	TYR M 421 MET M 384 ASN M 382 LEU M 381	None None A G 42 ( 4.1A) None	1.44A	3lslA-3zn8M: undetectable 3lslD-3zn8M: undetectable	3lslA-3zn8M: 22.83 3lslD-3zn8M: 22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSL_A_PZIA800_0 (GLUTAMATE RECEPTOR 2)	3zn8	SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN (Sulfolobus solfataricus)	4 / 7	TYR M 421 MET M 384 LEU M 381 SER M 407	None	1.38A	3lslA-3zn8M: undetectable 3lslD-3zn8M: undetectable	3lslA-3zn8M: 22.83 3lslD-3zn8M: 22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y03_B_SALB801_1 (PROTEIN POLYBROMO-1)	3zn8	SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN (Sulfolobus solfataricus)	4 / 5	LEU M 389 TYR M 421 ALA M 380 ILE M 403	None	1.11A	4y03B-3zn8M: undetectable	4y03B-3zn8M: 27.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C06_D_FI8D1404_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	3zn8	SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN (Sulfolobus solfataricus)	3 / 3	ARG M 426 LYS M 429 ARG M 330	None	1.23A	6c06D-3zn8M: undetectable	6c06D-3zn8M: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3LSL_A_PZIA800_0","GLUTAMATE RECEPTOR 2","3zn8","SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN","Sulfolobus solfataricus",4,"TYR M 421;MET M 384;ASN M 382;LEU M 381","None;None;  A G  42 ( 4.1A);None","1.44A","3lslA-3zn8M:undetectable;3lslD-3zn8M:undetectable","3lslA-3zn8M:22.83;3lslD-3zn8M:22.83"],["3LSL_A_PZIA800_0","GLUTAMATE RECEPTOR 2","3zn8","SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN","Sulfolobus solfataricus",4,"TYR M 421;MET M 384;LEU M 381;SER M 407","None","1.38A","3lslA-3zn8M:undetectable;3lslD-3zn8M:undetectable","3lslA-3zn8M:22.83;3lslD-3zn8M:22.83"],["4Y03_B_SALB801_1","PROTEIN POLYBROMO-1","3zn8","SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN","Sulfolobus solfataricus",4,"LEU M 389;TYR M 421;ALA M 380;ILE M 403","None","1.11A","4y03B-3zn8M:undetectable","4y03B-3zn8M:27.15"],["6C06_D_FI8D1404_1","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","3zn8","SIGNAL RECOGNITION PARTICLE 54 KDA PROTEIN","Sulfolobus solfataricus",3,"ARG M 426;LYS M 429;ARG M 330","None","1.23A","6c06D-3zn8M:undetectable","6c06D-3zn8M:undetectable"]]